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anti-Hypocretin (Orexin) Receptor 2 (HCRTR2) Antibodies

The protein encoded by HCRTR2 is a G-protein coupled receptor involved in the regulation of feeding behavior. Additionally we are shipping HCRTR2 Kits (7) and HCRTR2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HCRTR2 3062 O43614
HCRTR2 25605 P56719
HCRTR2 387285 P58308
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Top anti-HCRTR2 Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of Orexin receptor type 2 Antibody (Center) in J... Western blot analysis of Orexin receptor type 2 Antibody (Center) in m... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of HCRTR2 expression in transfected 293T cell li... 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB HCRTR2 Antibody (Center)  western blot analysis in Jurkat cell line ly... HCRTR2 Antibody (Center)  western blot analysis in mouse kidney tissue... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC (p) Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated IP Immunoprecipitation of HCRTR2 transfected lysate using anti-HCRTR2 Max... 100 μL Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated RNAi, ELISA, WB Western blot analysis of HCRTR2 over-expressed 293 cell line, cotransf... Detection limit for recombinant GST tagged HCRTR2 is approximately 0.0... 100 μg Log in to see 9 Days
$430.00
Details

HCRTR2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Mouse (Murine) , ,
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Top referenced anti-HCRTR2 Antibodies

  1. Human Monoclonal HCRTR2 Primary Antibody for WB - ABIN393222 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN393222

  2. Human Polyclonal HCRTR2 Primary Antibody for EIA, WB - ABIN953937 : Chen, Randeva: Genomic organization and regulation of the human orexin (hypocretin) receptor 2 gene: identification of alternative promoters. in The Biochemical journal 2010 (PubMed)
    Show all 4 references for ABIN953937

  3. Dog (Canine) Polyclonal HCRTR2 Primary Antibody for WB - ABIN374884 : Spinazzi, Rucinski, Neri, Malendowicz, Nussdorfer: Preproorexin and orexin receptors are expressed in cortisol-secreting adrenocortical adenomas, and orexins stimulate in vitro cortisol secretion and growth of tumor cells. in The Journal of clinical endocrinology and metabolism 2005 (PubMed)

More Antibodies against HCRTR2 Interaction Partners

Cow (Bovine) Hypocretin (Orexin) Receptor 2 (HCRTR2) interaction partners

  1. These data confirmed expression of orexin (show OX Antibodies) and its two receptors in the bovine adrenal gland.

Zebrafish Hypocretin (Orexin) Receptor 2 (HCRTR2) interaction partners

  1. Data show that fish lacking the hypocretin receptor demonstrate short and fragmented sleep in the dark, in striking contrast to the excessive sleepiness and cataplexy of narcolepsy in mammals.

Human Hypocretin (Orexin) Receptor 2 (HCRTR2) interaction partners

  1. our meta-analysis provides genetic evidence for a role of HCRTR2 in cluster headache

  2. Heart failure patients with minor allele for rs7767652, upstream of hypocretin (orexin) receptor-2 (HCRTR2), were less likely to have improved left ventricular function and a lower prevalence of ejection fraction >35%

  3. the nonsynonymous rs2653349 single nucleotide polymorphism (SNP) (located on the gene that encodes orexin (show OX Antibodies) [hypocretin (show OX Antibodies)] receptor 2) was selected as the most notable SNP associated with Fagerstrom Test for Nicotine Dependence.

  4. Antibodies from vaccine-associated narcolepsy sera cross-reacted with both influenza nucleoprotein and hypocretin receptor 2.

  5. using lipid-mediated crystallization and protein engineering with a novel fusion chimaera, the structure of the human OX2R bound to suvorexant at 2.5 A resolution is solved

  6. DQ B1 but not HLA-DR typing, TNF-alpha (show TNF Antibodies) levers, HCRTR1 (show HCRTR1 Antibodies) and HCRTR2 were higher in narcolepsy-cataplexy/schizophrenia patients.

  7. Both orexin (show OX Antibodies) receptor subtypes, OX1R (show HCRTR1 Antibodies) and OX2R, and CB1 (show CNR1 Antibodies) cannabinoid receptors are capable of forming constitutive homo- and heteromeric complexes.

  8. Orexinergic innervation and expression of genes encoding OX2R receptor are upregulated in transgenic mice at dusk.

  9. Expression of the OX2R protein was detected in normal endometrial epithelia, whereas it was frequently lacking in endometrial endometrioid carcinoma.

  10. [review] Native orexin (show OX Antibodies) peptides consist of receptor agonists, orexin-A (33 amino acids) and orexin-B (28 amino acids) (aka (show NEUROG1 Antibodies) hypocretin-1 and hypocretin (show OX Antibodies)-2).

Mouse (Murine) Hypocretin (Orexin) Receptor 2 (HCRTR2) interaction partners

  1. In an heart failure model, HCRTR2-deficient mice exhibited poorer cardiac function, worse treadmill exercise capacity, and greater myocardial scarring

  2. orexin (show OX Antibodies) activation of OX2R (show CD200R1 Antibodies) in the brain centrally enhances bone formation by lowing circulating leptin (show LEP Antibodies) level.

  3. OX2R (show CD200R1 Antibodies) activation induces PKC (show PKC Antibodies)-mediated ERK (show EPHB2 Antibodies) and CREB (show CREB1 Antibodies) phosphorylation.

  4. In the hypothalamus, the OX2 receptors have an inhibitory role in modulating basal concentrations of NE, ACh, and Hist. In the prefrontal cortex, the evoked release of the monoamines NE, 5-HT, and DA seems to be controlled negatively by OX2 receptors.

  5. results indicate that hcrtr1 (show HCRTR1 Antibodies) and 2 signaling oppose one another in the regulation of depression-like behaviors.

  6. Mice lacking OX2R (show CD200R1 Antibodies) signaling had poor maintenance of wakefulness indicative of sleepiness and fragmented sleep and lacked any electrophysiological response to orexin-A in the wake-promoting neurons of the tuberomammillary nucleus.

  7. activation of orexin (show OX Antibodies) neurons through OX2R (show CD200R1 Antibodies) might have an important role in the maintenance of arousal.

  8. Regulation of sleep/wake states is completely achieved by OX(2)R-expressing neurones without involving H(1)R-mediated pathways. Maintenance of basal physiological sleep/wake states is fully achieved without both H(1) and OX(1 (show NQO1 Antibodies)) receptors.

  9. So, the SAF (show PGS1 Antibodies) diet can alter adipocytic adiposity-related gene expression and result in effective amelioration of diet-induced obesity.

  10. hypocretin receptor 2 mRNA levels declined with age in the hippocampus, thalamus, pons, and medulla (hypocretin receptor 2)

Pig (Porcine) Hypocretin (Orexin) Receptor 2 (HCRTR2) interaction partners

  1. Immunoreactivity (IR) for both orexins A and B (OXA and OXB), and cognate receptors (OX1R (show HCRTR1 Antibodies) and OX2R) were identified only in the excretory striated (show NSDHL Antibodies) ducts of the MSG while acinar cells were not immunoreactive.

  2. Data demonstrated the presence of OX1R (show HCRTR1 Antibodies) and OX2R genes and proteins in the ovary of the pig and the impact of the hormonal milieu on the expression of both receptors.

  3. expression of OX1R (show HCRTR1 Antibodies) and Ox2R in hypothalamus during oestrous cycle; evidence OX1R (show HCRTR1 Antibodies) and OX2R mRNAs and proteins occur in hypothalamic structures engaged in control of reproduction; indicate dependence of OXR expression on endocrine reproductive state

  4. findings provide the first evidence that orexin (show OX Antibodies) receptors 1 and 2 messenger RNAs and proteins occur in the pituitary of the pig and indicate the dependence of orexin (show OX Antibodies) receptor expression on the endocrine reproductive state

HCRTR2 Antigen Profile

Protein Summary

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A.

Gene names and symbols associated with HCRTR2

  • hypocretin (orexin) receptor 2 (HCRTR2) antibody
  • hypocretin (orexin) receptor 2 (LOC100229747) antibody
  • hypocretin (orexin) receptor 2 (hcrtr2) antibody
  • orexin receptor 2 (LOC443181) antibody
  • hypocretin (orexin) receptor 2 (Hcrtr2) antibody
  • hcrtr antibody
  • LOC443181 antibody
  • LOC100229747 antibody
  • mOX2aR antibody
  • mOX2bR antibody
  • mOXR2 antibody
  • OX2R antibody

Protein level used designations for HCRTR2

orexin receptor type 2 , hypocretin (orexin) receptor 2 , orexin receptor type 2-like , hypocretin receptor 2 , orexin receptor 2 , hcrt receptor , hypocretin orexin receptor , hypocretin receptor , hypocretin receptor type 2 , orexin type-2 receptor , ox-2-R , ox2-R , hypocretin/orexin (Hcrt) receptor 2 , ox2R , ox2r

GENE ID SPECIES
529603 Bos taurus
100229747 Taeniopygia guttata
100392404 Callithrix jacchus
100457334 Pongo abelii
100495420 Xenopus (Silurana) tropicalis
100603910 Nomascus leucogenys
428644 Gallus gallus
443181 Ovis aries
462786 Pan troglodytes
561260 Danio rerio
3062 Homo sapiens
399545 Canis lupus familiaris
25605 Rattus norvegicus
387285 Mus musculus
397428 Sus scrofa
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