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The protein encoded by HPRT1 is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. Additionally we are shipping HPRT1 Proteins (35) and HPRT1 Kits (14) and many more products for this protein.
Showing 10 out of 154 products:
Human Polyclonal HPRT1 Primary Antibody for EIA, WB - ABIN453114
Ceballos-Picot, Mockel, Potier, Dauphinot, Shirley, Torero-Ibad, Fuchs, Jinnah: Hypoxanthine-guanine phosphoribosyl transferase regulates early developmental programming of dopamine neurons: implications for Lesch-Nyhan disease pathogenesis. in Human molecular genetics 2009
Show all 2 references for ABIN453114
Human Monoclonal HPRT1 Primary Antibody for ELISA, WB - ABIN969197
Manjanatha, Shelton, Bishop, Shaddock, Dobrovolsky, Heflich, Webb, Blankenship, Beland, Greenlees, Culp: Analysis of mutations and bone marrow micronuclei in Big Blue rats fed leucomalachite green. in Mutation research 2004
Chicken Polyclonal HPRT1 Primary Antibody for WB - ABIN2783383
Yamada: [Deficiencies of hypoxanthine guanine phosphoribosyltransferase (HPRT)]. in Nihon rinsho. Japanese journal of clinical medicine 2008
Human Polyclonal HPRT1 Primary Antibody for WB - ABIN4890030
Wu, Bond, Chen, Chen, Li, Shohet, Wright: HIF-1α in the heart: remodeling nucleotide metabolism. in Journal of molecular and cellular cardiology 2015
Human Monoclonal HPRT1 Primary Antibody for ELISA, WB - ABIN561360
Hayashi, Naoi, Nakagawa, Nishikawa, Fukuda, Imajoh-Ohmi, Kondo, Kubo, Yabuki, Hattori, Hirouchi, Sugiyama: Sorting nexin 27 interacts with multidrug resistance-associated protein 4 (MRP4) and mediates internalization of MRP4. in The Journal of biological chemistry 2012
six metabolites with significantly different contents in wild-type and HPRT-deficient mice, were found.
In the HGprt-deficient mouse model, stains for tyrosine hydroxylase (TH (show TH Antibodies)) reveal no obvious loss of midbrain dopamine neurons, but quantitative immunoblots reveal reduced TH expression in the striatum.
HPRT-deficiency alters cAMP/PKA signaling pathway, which is in part due to the increased of PDE10A (show PDE10A Antibodies) expression and activi
Hprt is proposed as a reference gene for analysis of gene expression in neural developmental issues of the murine neocortex.
Data indicate that Ubc (show UBA52 Antibodies) and Ywhaz (show YWHAZ Antibodies) were best correlated for cB cells and lymphocytes, whereas Ubc (show UBA52 Antibodies) and Gapdh (show GAPDH Antibodies) were the best combination for non-B cells, and Actb (show ACTB Antibodies) and Hprt1 were the least stably expressed genes for B cells and non-B cell.
Data indicate that Hprt, Rpl13a (show RPL13A Antibodies) and Tpt1 (show TPT1 Antibodies) are a set of stably expressed reference genes for accurate gene expression normalization in myocardial infarction studies in mice.
These results demonstrate that PRTFDC1 (show PRTFDC1 Antibodies) is a genetic modifier of HPRT-deficiency in the mouse.
ionizing radiation-induced mutant phenotype plasticity is not dependent on DNA methylation (show HELLS Antibodies) of the hypoxanthine phosphoribosyl transferase gene in mouse FM3A cells
the characterization of Hprt mutations in vivo in Blm hypomorphic mice
Hprt mutant frequencies were determined in aging male rats on caloric restriction diets.
Pseudogene-free amplification of HPRT1 in quantitative reverse transcriptase polymerase chain reaction.
HPRT gene mutation assay demonstrated that surface chemical composition plays a significant role in silver nanoparticle toxicity.
Lesch-Nyhan Syndrome in a Family with a Deletion Followed by an Insertion within the HPRT1 Gene
A highly significant correlation between six metabolites and the HGprt deficiency was established, each of them providing an easily measurable marker of the disease.
HPRT mutations are not increased by systemic depleted uranium exposure.
13 novel mutations in Saudi Arabian HPRT-related hyperuricemia patients manifesting different levels of uric acid.
HPRT1 mutations in new Japanese families and PRPP concentration
In the study presented here, for the first time T-705/favipiravir absolutely depends on the cellular HGPRT enzyme to exert its anti-influenza virus activity in mammalian cells.
Molecular genetic testing revealed a new frameshift mutation in the HPRT1 gene causing Lesch-Nyhan syndrome in an Indian family.
study reports three novel independent mutations in the coding region of HPRT gene: exon 3: c.141delA, p.D47fs53X; exon 5: c.400G>A, p.E134K; exon 7: c.499A>G, p.R167G from three Lesch-Nyhan syndrome affected male patients
levels of G6PD (show G6PD Antibodies) and HPRT RNA were higher in female morulae and blastocysts than in males
The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.
, HPRT B
, hypoxanthine guanine phosphoribosyl transferase 1
, hypoxanthine-guanine phosphoribosyltransferase
, phosphoribosyl transferase domain containing 1
, hypoxanthine guanine phosphoribosyl transferase
, hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)
, hypoxanthine-guanine phosphoribosyltransferase 1
, hypoxanthine phosphoribosyltransferase 1 [(Lesch-Nyhan syndrome)
, hypoxanthine phosphoribosyl transferase