Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
HIF1A encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. Additionally we are shipping Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) Kits (83) and Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) Proteins (50) and many more products for this protein.
Showing 10 out of 448 products:
Cow (Bovine) Monoclonal HIF1A Primary Antibody for ICC, IF - ABIN863097
Surazynski, Miltyk, Prokop, Palka: The effect of estrogen on prolidase-dependent regulation of HIF-1α expression in breast cancer cells. in Molecular and cellular biochemistry 2013
Show all 9 references for ABIN863097
Human Polyclonal HIF1A Primary Antibody for WB - ABIN1881413
Espinosa, José Carnicer, Catasus, Canet, Dangelo, Zannoni, Prat: Myometrial invasion and lymph node metastasis in endometrioid carcinomas: tumor-associated macrophages, microvessel density, and HIF1A have a crucial role. in The American journal of surgical pathology 2010
Show all 5 references for ABIN1881413
Human Polyclonal HIF1A Primary Antibody for IF (p), IHC (p) - ABIN672546
Shou, Lin, Liang, Li, Chen: Expression and prognosis of FOXO3a and HIF-1? in nasopharyngeal carcinoma. in Journal of cancer research and clinical oncology 2012
Show all 5 references for ABIN672546
Human Polyclonal HIF1A Primary Antibody for IF, IHC (p) - ABIN392176
Favaro, Nardo, Persano, Masiero, Moserle, Zamarchi, Rossi, Esposito, Plebani, Sattler, Mann, Mueller-Klieser, Ciminale, Amadori, Indraccolo: Hypoxia inducible factor-1alpha inactivation unveils a link between tumor cell metabolism and hypoxia-induced cell death. in The American journal of pathology 2008
Show all 3 references for ABIN392176
Human Monoclonal HIF1A Primary Antibody for ICC, IHC - ABIN969193
Mounier, Pialoux, Roels, Thomas, Millet, Mercier, Coudert, Fellmann, Clottes: Effect of intermittent hypoxic training on HIF gene expression in human skeletal muscle and leukocytes. in European journal of applied physiology 2009
Show all 2 references for ABIN969193
Human Polyclonal HIF1A Primary Antibody for FACS, IF - ABIN652389
Lee, Lee, Kim, Kim, Jung, Seo, Park, Choi, Yim, Lee, Park, Yoo, Kim, Lee, Kim, Ryeom, Kim, Oh: Roles of arrest-defective protein 1(225) and hypoxia-inducible factor 1alpha in tumor growth and metastasis. in Journal of the National Cancer Institute 2010
Show all 2 references for ABIN652389
Human Monoclonal HIF1A Primary Antibody for EMSA, IF - ABIN114960
Arany, Huang, Eckner, Bhattacharya, Jiang, Goldberg, Bunn, Livingston: An essential role for p300/CBP in the cellular response to hypoxia. in Proceedings of the National Academy of Sciences of the United States of America 1996
Show all 2 references for ABIN114960
Human Polyclonal HIF1A Primary Antibody for EIA, IHC (p) - ABIN360059
Alexandru, Graumann, Smith, Kolawa, Fang, Deshaies: UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover. in Cell 2008
Show all 2 references for ABIN360059
Chicken Polyclonal HIF1A Primary Antibody for WB - ABIN2780373
Kitajima, Ide, Ohtsuka, Miyazaki: Induction of hepatocyte growth factor activator gene expression under hypoxia activates the hepatocyte growth factor/c-Met system via hypoxia inducible factor-1 in pancreatic cancer. in Cancer science 2008
In this review, mouse models of sleep apnea show that disruption of HIF-1alpha (and HIF-2alpha (show EPAS1 Antibodies)) balance results in hypertension.
Hif-1alpha is a key regulator in the metabolic adaptation to high-intensity training
SART1 (show SART1 Antibodies)(+/-) mice showed significant up-regulation of HIF-1alpha in circulating and liver-infiltrating immune cells
OGA (show MGEA5 Antibodies) plays a critical role in placental vasculogenesis by modulating HIF-1alpha stabilization.
the involvement of PAI-1 (show SERPINE1 Antibodies) in HIF-1-enhanced thrombosis and that an additional factor participates in regulating Pai-1 (show SERPINE1 Antibodies) expression in compressed skin.
In conclusion, saturated free fatty acid induced proinflammatory cytokine production partly through activation of a novel lactate-HIF1alpha pathway in chondrocytes.
suggest that tumor and endothelial cell-specific HIF1alpha may have opposing roles in cancer-associated coagulation and thrombosis.
HIF1alpha has a role in inflammation in a mouse model of proximal colon cancer
exposure of primary hepatocytes to hypoxia or transgenic overexpression of HIF-1alpha in the mouse liver was sufficient to induce the expression of FABP4 (show FABP4 Antibodies).
Dll4 (show DLL4 Antibodies)/Notch (show NOTCH1 Antibodies) signaling and HIF-1alpha are closely related to lymphangiogenesis in dry eye-induced lacrimal glands.
These results suggested that fucosterol executed its protective effects against CoCl2 induced cytotoxicity and inflammation by the inhibition of hypoxia inducible factor through PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) pathway.
IL-1b (show IL1B Antibodies), which normally bridges innate and adaptive immunity, induces the production of the major haematopoietic/proleukaemic growth factor SCF (show KITLG Antibodies) through the PI-3K/mTOR (show FRAP1 Antibodies) pathway and the HIF-1a transcription complex.
Pretreatment expression of thymidine phosphorylase (show TYMP Antibodies)/HIF-1alpha were found to predict pathologic response and outcomes in clinical stage II/III rectal cancer receiving neoadjuvant chemoradiotherapy.
HIF-dependent regulation of ITGA6 (show ITGA6 Antibodies) is one mechanism by which sorting for CD49f (show ITGA6 Antibodies) (+) cells enhances cancer stem cells.
Inactivation of HIF-1alpha impairs chemotaxis and cell adhesion to stroma, reduces bone marrow and spleen colonization, regulates cell interaction with tumor microenvironment.
regulation of HIF-1alpha expression in CD4 (show CD4 Antibodies)(+) T cells in hypoxia gravely relies on its transcriptional upregulation and subsequent enhanced protein stabilization.
in hypoxic pancreatic tumors PKM2 interferes both with NF-kappaB (show NFKB1 Antibodies)/p65 (show GORASP1 Antibodies) and HIF-1alpha activation that ultimately triggers VEGF-A (show VEGFA Antibodies) secretion and subsequent blood vessel formation.
Data show that c-mdm2 (show MDM2 Antibodies) proto-ocogene protein (MDM2 (show MDM2 Antibodies)) expression levels were correlated with hypoxia-inducible factor 1, alpha subunit (show POLG Antibodies) (HIF1alpha) levels, necrosis and proliferation index in malignant pleural mesothelioma.
Data show that estrogen receptor beta (ERbeta (show ESR2 Antibodies)) functions as a repressor of hypoxia-inducible factor 1, alpha subunit (show POLG Antibodies) (HIF-1alpha)-mediated NF-kappa B (show NFKB1 Antibodies) (NF-kB) activation.
there is a hypoxia response element (HRE) in the nNOS (show NOS1 Antibodies) promoter, to which HIF-1alpha may bind. CoCl2 enhanced the HIF-1alpha expression and its binding to this HRE, increasing the transcriptional activity of the nNOS (show NOS1 Antibodies) promoter.
Upregulation of VEGF (show VEGFA Antibodies) during hypoxia in chondrocyte is mediated partially through HIF-1alpha.
HIF-1alpha activates Sox9 (show SOX9 Antibodies) expression and enhances Sox9 (show SOX9 Antibodies)-mediated transcriptional activity.
Intramyocardial delivery of mesenchymal stem cells seems to trigger the release of angiogenic HIF-1alpha more effectively than does intracoronary delivery.
immunostaining for HIF-1alpha and HIF-2alpha (show EPAS1 Antibodies) was observed during endochondral ossification, whereas only HIF-2alpha (show EPAS1 Antibodies) was present at sites of intramembranous ossification
Downregulation of miR (show MYLIP Antibodies)-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 (show SIRT1 Antibodies) and recapitulates hypoxia preconditioning in cardiac myocytes.
Viable chondrocytes in the superficial layer of the epiphyseal cartilage showed HIF-1alpha activation and VEGF upregulation with subsequent revascularization occurring in the cartilage.
Hypoxia increased the amounts of HIF1A protein, VEGF mRNA and VEGF protein in cultured bovine luteal cells.
hypoxia-induced changes in vascular cell growth are altered by hyperglycemia via inhibition of HIF-1alpha expression and activity
VEGF has an effect on the expression of its own transcription factor, HIF-1, and on VEGF itself
Identify sphingosine-1-phosphate as a novel and potent nonhypoxic activator of HIF-1.
Suggest supplemental oxygen inhibits HIF-1alpha/VEGF signaling to reduce smooth muscle proliferation in rabbit arteriovenous fistula model.
HIF-1alpha-induced HSP70 (show HSP70 Antibodies) overexpression increased the expression levels of ECM (show MMRN1 Antibodies) genes and cell viability, and protected chondrocytes from apoptosis. HIF-1alpha may regulate anabolic effects of chondrocytes under hypoxic conditions by regulating HSP70 (show HSP70 Antibodies) expression
Transcatheter arterial embolization of liver tumors increases the expression of HIF-1alpha at protein level in the residual viable tumor.
Upregulation of HIF-1 protects cardiac myocyte function after ischemia/reperfusion by maintaining calcium release.
HIF-1alpha expression in early atherosclerosis can promote the formation of neovascularization.
Xells respond to hypoxia through a transcription factor, hypoxia-inducible factor 1
Upregulation of HIF-1 could protect isolated cardiac myocytes against nitrate tolerance through a cyclic GMP protein kinase-independent mechanism and through a kinase-dependent mechanism in myocardial stunning.
rhEPO can down-regulate HIF-1alpha expression in the retina of rabbits with acute high intraocular pressure.
Increased HIF-1 alpha protects the functional effects of cyclic GMP thorough maintenance of cyclic GMP protein kinase activity after ischemic-reperfusion
HIF-1-mediated activation of 5-HT (show DDC Antibodies) signalling promotes axon regeneration by activating both the RhoA (show RHOA Antibodies) and cAMP pathways.
this study reports that neuronal stabilization of HIF-1 mediates these effects in Caenorhabditis elegans through a cell nonautonomous signal to the intestine, which results in activation of the xenobiotic detoxification enzyme flavin-containing monooxygenase-2 (FMO-2 (show FMO2 Antibodies)).
AMPK (show PRKAA1 Antibodies) and HIF-1 may control immunity and longevity tightly by acting as feedback regulators of ROS (show ROS1 Antibodies)
Growth in hypoxia increases longevity in wild-type worms but not in animals lacking HIF-1 or DAF-16. Conversely, hypoxia shortens life span in combination with overexpression of the antioxidant stress response protein SKN-1.
Increased levels of hydrogen peroxide induce a HIF-1-dependent modification of lipid metabolism in AMPK (show PRKAA1 Antibodies) compromised C. elegans dauer larvae.
These data show that HIF-1 regulates intestinal iron homeostasis during iron deficiency by activating and inhibiting genes involved in iron uptake and storage.
Data indicate that genes sqrd-1, ethe-1 (show ETHE1 Antibodies), cysl-1, cysl-2 and HIF-1 are involved in survival to hydrogen sulfide (show SQRDL Antibodies) and hydrogen cyanide.
Data show that stabilization of HIF-1 increases life span robustly under all conditions tested; however, deletion of hif-1 increases life span in a temperature-dependent manner.
Data show that that reactive oxygen species (ROS (show ROS1 Antibodies)) are increased in respiration mutants and that mild increases in ROS (show ROS1 Antibodies) can stimulate HIF-1 to activate gene expression and promote longevity.
These data support a model in which SWAN-1 (show DCAF7 Antibodies), MBK-1 and EGL-9 regulate HIF-1 transcriptional activity and modulate C. elegans resistance to P. aeruginosa PAO1 (show SMOX Antibodies) fast killing.
This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
, HIF1 alpha
, Hypoxia-inducible factor 1 alpha
, hypoxia-inducible factor 1-alpha
, ARNT-interacting protein
, ARNT interacting protein
, PAS domain-containing protein 8
, basic-helix-loop-helix-PAS protein MOP1
, class E basic helix-loop-helix protein 78
, hypoxia-inducible factor 1 alpha isoform I.3
, hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
, hypoxia-inducible factor1alpha
, member of PAS protein 1
, member of PAS superfamily 1
, hypoxia-inducible factor 1 alpha
, hypoxia inducible factor 1 alpha subunit
, hypoxia inducible factor 1, alpha subunit