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IMP (Inosine 5'-Monophosphate) Dehydrogenase 1 Proteins (IMPDH1)

The protein encoded by IMPDH1 acts as a homotetramer to regulate cell growth. Additionally we are shipping IMPDH1 Antibodies (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IMPDH1 362329  
IMPDH1 3614 P20839
Mouse IMPDH1 IMPDH1 23917 P50096
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Top IMPDH1 Proteins at antibodies-online.com

Showing 3 out of 6 products:

Catalog No. Origin Source Conjugate Quantity Supplier Delivery Price Details
Yeast Rat His tag 1 mg Log in to see 56 to 66 Days
$3,457.67
Details
HOST_Human Human Un-conjugated 20 μg Log in to see 9 to 11 Days
$785.40
Details
Human Un-conjugated 2 μg Log in to see 6 Days
$168.54
Details

IMPDH1 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human

More Proteins for IMP (Inosine 5'-Monophosphate) Dehydrogenase 1 (IMPDH1) Interaction Partners

Human IMP (Inosine 5'-Monophosphate) Dehydrogenase 1 (IMPDH1) interaction partners

  1. In our cohort of >300 familial cases of autosomal-recessive retinitis pigmentosa, PKRP004 is the only family harboring a mutation in IMPDH1.

  2. A novel mutation, p.L270R in IMPDH1, was found to be retinitis pigmentosa-causing in one family.

  3. p53 (show TP53 Proteins) has a novel function in regulating purine biosynthesis, aided by miR (show MLXIP Proteins)-34a-dependent IMPDH repression.

  4. IMPDH1 mutation is associated with retinitis pigmentosa.

  5. The mutation frequency of IMPDH1 gene of the Han population in Ganzhou city was similar as approximately 2-5% of the autosomal dominant retinitis pigmentosa cases among Americans of European origin and Europeans.

  6. resequenced IMPDH1 and IMPDH2 (show IMPDH2 Proteins) using DNA from 288 individuals from three ethnic groups and performed functional genomic studies of the sequence variants observed; identified 73 single nucleotide polymorphisms in IMPDH1, 59 novel

  7. Inosine 5'-monophosphate dehydrogenase 1 haplotypes have a role in mycophenolate mofetil gastrointestinal intolerance in pediatric heart transplant patients

  8. The risk of subclinical acute rejection for recipients who cannot adapt in therapeutic drug monitoring of mycophenolic acid seems to be influenced by IMPDH1 rs2278293 polymorphism.

  9. In this small sample of pediatric heart transplant patients receiving MMF, ABCC2, IMPDH1 and IMPDH2 SNPs were associated with MMF GI intolerance and bone marrow toxicity.

  10. A novel IMPDH1 gene mutation (Arg231Pro) was associated with a severe form of autosomal dominant retinitis pigmentosa.

Cow (Bovine) IMP (Inosine 5'-Monophosphate) Dehydrogenase 1 (IMPDH1) interaction partners

  1. IMP dehydrogenase type 1 associates with polyribosomes translating rhodopsin mRNA

Mouse (Murine) IMP (Inosine 5'-Monophosphate) Dehydrogenase 1 (IMPDH1) interaction partners

  1. We conclude that both IMPDH and HPRT (show HPRT1 Proteins) activities contribute to normal T-lymphocyte activation and function

  2. Retinitis pigmentosa-causing mutations identified in IMPDH1 gene. High level of IMPDH1 in photoreceptors, low levels in other layers of retina.

  3. IMPDH1 mutations cause photoreceptor degeneration in retinitis pigmentosa

IMPDH1 Protein Profile

Protein Summary

The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with IMPDH1

  • IMP (inosine 5'-monophosphate) dehydrogenase 1 (IMPDH1)
  • IMP (inosine 5'-monophosphate) dehydrogenase 1 (impdh1)
  • IMP (inosine 5'-monophosphate) dehydrogenase 1 (Impdh1)
  • inosine 5'-phosphate dehydrogenase 1 (Impdh1)
  • B930086D20Rik protein
  • IMPD protein
  • IMPD 1 protein
  • IMPD1 protein
  • IMPDH 1 protein
  • LCA11 protein
  • RP10 protein
  • sWSS2608 protein

Protein level used designations for IMPDH1

IMP (inosine 5'-monophosphate) dehydrogenase 1 , IMP (inosine monophosphate) dehydrogenase 1-like , IMP (inosine monophosphate) dehydrogenase 1 , inosine-5'-monophosphate dehydrogenase 1-like , IMP dehydrogenase 1 , inosine 5'-phosphate dehydrogenase 1 , inosine monophosphate dehydrogenase 1 , inosine-5'-monophosphate dehydrogenase 1 , IMPD 1 , IMPDH 1 , IMPDH-I

GENE ID SPECIES
100357217 Oryctolagus cuniculus
100399106 Callithrix jacchus
100442769 Pongo abelii
100480976 Ailuropoda melanoleuca
463864 Pan troglodytes
100552361 Anolis carolinensis
100583696 Nomascus leucogenys
362329 Rattus norvegicus
3614 Homo sapiens
504305 Bos taurus
23917 Mus musculus
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