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anti-IQ Motif and Sec7 Domain 2 (IQSEC2) Antibodies

IQSEC2 encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IQSEC2 23096 Q5JU85
IQSEC2 245666 Q5DU25
IQSEC2 685244  
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Top anti-IQSEC2 Antibodies at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: IQSEC2  Sample Tissue: MDA-MB-435S Whole Cell lysates  Antibody Dilution: 1.0 µg/mL IQSEC2 is supported by BioGPS gene expression data to be expressed in MDA-MB435 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-IQSEC2 antibody IHC staining of human tonsil, germinal center. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1102602 dilution 5 ug/ml. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, ELISA   100 μg Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Mouse Un-conjugated WB Western Blot analysis of IQSEC2 expression in transfected 293T cell line by IQSEC2 MaxPab polyclonal antibody.Lane 1: IQSEC2 transfected lysate(104.39 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

IQSEC2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against IQSEC2 Interaction Partners

Human IQ Motif and Sec7 Domain 2 (IQSEC2) interaction partners

  1. This study demonstrates a dual role of BRAG1 in synaptic function.

  2. Truncating mutations in IQSEC2 are responsible for syndromic severe intellectual disability in male patients.

  3. data supports recently published data suggesting that IQSEC2 plays a more significant role in the development of X-linked intellectual disability with seizures than previously anticipated.

  4. Here we show that a mutation of IQSEC2, encoding a guanine nucleotide exchange factor (show RASGRF1 Antibodies) for the ADP-ribosylation factor (show ARF1 Antibodies) family of small GTPases, caused this disorder

Mouse (Murine) IQ Motif and Sec7 Domain 2 (IQSEC2) interaction partners

  1. Our present findings suggest that IQ-ArfGEF/BRAG1 may play roles downstream of NMDA receptors through the interaction with multivalent PSD (show PSD Antibodies) proteins such as IRSp53 (show BAIAP2 Antibodies) and PSD-95 (show DLG4 Antibodies).(BRAG1 PROTEIN, MOUSE)

  2. Iqsec2 (BRAG2 (show IQSEC1 Antibodies))-mediated Arf6 (show ARF6 Antibodies) activation triggered by AMPA (show GRIA3 Antibodies) receptors is the convergent step of different forms of long-term depression and provides an essential mechanism for the control of vesicle formation by endocytic cargo.

IQSEC2 Antigen Profile

Protein Summary

This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with IQSEC2

  • IQ motif and Sec7 domain 2 (IQSEC2) antibody
  • IQ motif and Sec7 domain 2 (Iqsec2) antibody
  • Brag1 antibody
  • mKIAA0522 antibody
  • MRX1 antibody
  • RGD1562109 antibody

Protein level used designations for IQSEC2

IQ motif and SEC7 domain-containing protein 2 , brefeldin A resistant Arf-guanine nucleotide exchange factor 1 , brefeldin A resistant Arf-guanine nucleotide exchange factor 1b , brefeldin A resistant Arf-guanine nucleotide exchange factor 1c

GENE ID SPECIES
23096 Homo sapiens
245666 Mus musculus
685244 Rattus norvegicus
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