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IQ Motif and Sec7 Domain 2 (IQSEC2) ELISA Kits

IQSEC2 encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. Additionally we are shipping IQSEC2 Antibodies (21) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human IQSEC2 IQSEC2 23096 Q5JU85
Anti-Mouse IQSEC2 IQSEC2 245666 Q5DU25
Anti-Rat IQSEC2 IQSEC2 685244  
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More ELISA Kits for IQSEC2 Interaction Partners

Human IQ Motif and Sec7 Domain 2 (IQSEC2) interaction partners

  1. This study demonstrates a dual role of BRAG1 in synaptic function.

  2. Truncating mutations in IQSEC2 are responsible for syndromic severe intellectual disability in male patients.

  3. data supports recently published data suggesting that IQSEC2 plays a more significant role in the development of X-linked intellectual disability with seizures than previously anticipated.

  4. Here we show that a mutation of IQSEC2, encoding a guanine nucleotide exchange factor (show RASGRF1 ELISA Kits) for the ADP-ribosylation factor (show ARF1 ELISA Kits) family of small GTPases, caused this disorder

Mouse (Murine) IQ Motif and Sec7 Domain 2 (IQSEC2) interaction partners

  1. Our present findings suggest that IQ-ArfGEF/BRAG1 may play roles downstream of NMDA receptors through the interaction with multivalent PSD (show PSD ELISA Kits) proteins such as IRSp53 (show BAIAP2 ELISA Kits) and PSD-95 (show DLG4 ELISA Kits).(BRAG1 PROTEIN, MOUSE)

  2. Iqsec2 (BRAG2)-mediated Arf6 (show ARF6 ELISA Kits) activation triggered by AMPA (show GRIA3 ELISA Kits) receptors is the convergent step of different forms of long-term depression and provides an essential mechanism for the control of vesicle formation by endocytic cargo.

IQSEC2 Antigen Profile

Antigen Summary

This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with IQSEC2

  • IQ motif and Sec7 domain 2 (IQSEC2) antibody
  • IQ motif and Sec7 domain 2 (Iqsec2) antibody
  • Brag1 antibody
  • mKIAA0522 antibody
  • MRX1 antibody
  • RGD1562109 antibody

Protein level used designations for IQSEC2

IQ motif and SEC7 domain-containing protein 2 , brefeldin A resistant Arf-guanine nucleotide exchange factor 1 , brefeldin A resistant Arf-guanine nucleotide exchange factor 1b , brefeldin A resistant Arf-guanine nucleotide exchange factor 1c

GENE ID SPECIES
23096 Homo sapiens
245666 Mus musculus
685244 Rattus norvegicus
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