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anti-Iduronate 2-Sulfatase (IDS) Antibodies

Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Additionally we are shipping IDS Kits (28) and IDS Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IDS 3423 P22304
IDS 15931 Q08890
IDS 363513  
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Top anti-IDS Antibodies at antibodies-online.com

Showing 10 out of 81 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-IDS AntibodyTitration: 1.0 µg/mL  Positive Control: Hela Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-IDS mouse monoclonal antibody (ABIN2455529) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IDS (RC219187). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IDS (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-IDS. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-IDS mouse monoclonal antibody (ABIN2455541) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IDS (RC219187). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IDS (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-IDS. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-IDS mouse monoclonal antibody (ABIN2455542) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IDS (RC219187). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IDS (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-IDS. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-Iduronate 2 sulfatase antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: SMMC Cell Lysate Lane 3: A549 Cell Lysate Lane 4: MCF-7 Cell Lysate Lane 5: COLO Cell Lysate Anti-Iduronate 2 sulfatase antibody, IHC(P) IHC(P): Human Placenta Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Mouse Un-conjugated FACS, IF, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 8 to 10 Days
$463.83
Details

IDS Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against IDS Interaction Partners

Zebrafish Iduronate 2-Sulfatase (IDS) interaction partners

  1. Data demonstrate that iduronate sulfatase plays a critical role during early vertebrate development and its downregulation may be responsible for severe developmental defects, including a misshapen trunk and abnormal craniofacial cartilages.

Human Iduronate 2-Sulfatase (IDS) interaction partners

  1. This study evaluated a novel mutation in the IDS gene among 8 male Hunter syndrome patients; there was a quantitative deficiency of NK and B cell with normal responses in other immune parameters.

  2. 30 novel iduronate sulfatase mutations have been identified in mucopolysaccharidosis type II Latin American patients.

  3. Identification of a splice site mutation in the IDS gene associated with mucopolysaccharidosis type II.

  4. a novel (p.R468P) and five known (p.R88C, p.D148V, p.G224A, p.Y348X, and p.R468Q) IDS mutations were shown to result in proteins with little or no IDS activity and altered protein processing, when expressed in COS7 cells

  5. A report of a novel IDS nonsense mutation resulting in mucopolysaccharidosis type II in several patients from a Chinese family.

  6. genetically analyze patients with severe Hunter syndrome that showed a total deletion of the iduronate-2-sulphatase (IDS) gene

  7. Family members with 3 generations of X-inactivation with Hunter syndrome have 1568A>G missence mutation in the IDS gene

  8. LCR-initiated rearrangements at the IDS locus, completed with Alu-mediated recombination or non-homologous end joining

  9. Hunter syndrome in Thailand is caused by a diverse set of defects affecting both IDS protein production and activity.

  10. The in vivo correction of heritable gene lesions at the RNA level operating via a correction mechanism akin to RNA-editing, was observed for IDS mutant transcript.

Mouse (Murine) Iduronate 2-Sulfatase (IDS) interaction partners

  1. While the iduronate 2-sulfatase sp replacement results in increased enzyme secretion, the addition of the ApoB (show APOB Antibodies)-BD allows efficient BBB (show ALMS1 Antibodies) transcytosis and restoration of sulphamidase (show SGSH Antibodies) activity in the brain of treated mice.

  2. Iduronate-2-sulfatase (IDS) is localized in lysosomes in pancreatic islet cells and expression is regulated by glucose (show ZNF236 Antibodies). IDS has a potential role in the normal pathway of lysosomal degradation of secretory peptides.

  3. Ids crossing the blood-brain barrier corrects CNS defects in MPSII mice.

IDS Antigen Profile

Protein Summary

Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.

Gene names and symbols associated with IDS

  • iduronate 2-sulfatase (IDS) antibody
  • iduronate 2-sulfatase (CpipJ_CPIJ004938) antibody
  • iduronate 2-sulfatase (ids) antibody
  • iduronate 2-sulfatase (Ids) antibody
  • AW214631 antibody
  • MPS2 antibody
  • SIDS antibody
  • zgc:158245 antibody

Protein level used designations for IDS

iduronate 2-sulfatase (Hunter syndrome) , iduronate-2-sulfatase , iduronate 2-sulfatase , iduronate 2-sulfatase-like , alpha-L-iduronate sulfate sulfatase , iduronate 2-sulfatase 14 kDa chain , iduronate 2-sulfatase 42 kDa chain , idursulfase , iduronate sulfatase

GENE ID SPECIES
465896 Pan troglodytes
492194 Canis lupus familiaris
541272 Bos taurus
700892 Macaca mulatta
6036406 Culex quinquefasciatus
100135738 Xenopus (Silurana) tropicalis
100356659 Oryctolagus cuniculus
100415225 Callithrix jacchus
100435640 Pongo abelii
100469837 Ailuropoda melanoleuca
559959 Danio rerio
3423 Homo sapiens
15931 Mus musculus
363513 Rattus norvegicus
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