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anti-Iduronidase, alpha-L- (IDUA) Antibodies

IDUA encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. Additionally we are shipping IDUA Kits (16) and IDUA Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IDUA 360904  
IDUA 3425 P35475
IDUA 15932  
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Top anti-IDUA Antibodies at antibodies-online.com

Showing 10 out of 58 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB IDUA Antibody (Center) (ABIN651536) western blot analysis in Hela cell line lysates (35 µg/lane). This demonstrates the IDUA antibody detected the IDUA protein (arrow). IDUA Antibody (Center) (ABIN651536) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain tissue probed with Anti-IDUA Polyclonal Antibody (ABIN1713845) at a dilution of 1:200 overnight at 4°C, followed by Goat Anti-Rabbit secondary, Cy3 conjugated at 1:200 dilution for 40 minutes at 100 μL Log in to see 14 to 21 Days
$269.50
Details
Human Sheep Biotin WB   50 μg Log in to see 8 to 10 Days
$1,035.83
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Sheep Un-conjugated IP, ELISA, WB   100 μg Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

IDUA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Human , , ,
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Mouse (Murine) , ,


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More Antibodies against IDUA Interaction Partners

Zebrafish Iduronidase, alpha-L- (IDUA) interaction partners

  1. In the absence of Fgfrl1a, larvae fail to express the transcription factor glial cells missing 2 (gcm2 (show GCM2 Antibodies)), a gene necessary for cartilage and gill filament formation, in the ectodermal lining of the branchial arches.

Human Iduronidase, alpha-L- (IDUA) interaction partners

  1. A new IDUA variant that alters the structure of the signal peptide associated with mucopolysaccharidosis type I is reported.

  2. Amino acid substitutions in alpha-L-iduronidase determine the severity of mucopolysaccharidosis type I.

  3. The alpha-L-iduronidase missense mutation causing L238Q substitution, when paired with a nonsense mutation, is associated with significant, late-onset brain disease.

  4. We conclude that this procedure for determining residual IDUA activity in fibroblasts of MPS I patients may be helpful to predict MPS I phenotype.

  5. The IDUA structures and biochemical analysis of the disease-relevant P533R mutation have enabled us to correlate the effects of mutations in IDUA to clinical phenotypes.

  6. Data show that alpha-l-iduronidase (hIDUA) enzyme activity was highly correlated with the N-glycan attached to N372.

  7. X-ray diffraction analysis of human alpha-L-iduronidase

  8. Transfer of a high level of human alpha-L-iduronidase gene into the central nervous system (CNS) of MPS I mutant mice susceptible to mucopolysaccharidosis (MPS) improves the outcome for MPS when a high level of CNS gene expression is achieved.

  9. A previously unreported IDUA splice site mutation (NG_008103.1:g.21632G>C; NM_000203.3:c.1727+3G>C) causing a Hurler phenotype in a patient heterozygous for the common p.Q70X (NG_008103.1:g.5862C>T) mutation.

  10. This paper, showed a heterogeneous pattern of mutations and polymorphisms in the IDUA gene among Tunisian patients.

Mouse (Murine) Iduronidase, alpha-L- (IDUA) interaction partners

  1. This study demonstrated that the distribuation of bis (show BAG3 Antibodies)(monoacylglycero)phosphate in brain of mucopolysaccharidosis 1 (Hurler) mouse.

  2. Mucopolysaccharidosis type I, unique structure of accumulated heparan sulfate and increased N-sulfotransferase activity in mice lacking alpha-l-iduronidase.

  3. Studies show that mouse Idua-W392X mutation is analogous to the human IDUA-W402X mutation commonly found in MPS I-H patients.

  4. Data show that late-stage erythroid cells, transduced with a tissue-specific lentiviral vector, can deliver alpha-L-iduronidase continuously and can correct the disease phenotype in both viscera and CNS of MPS I mice.

  5. The results indicate that Idua(-/-) mice present deficits in long-term memory for aversive training and reduced exploratory behavior.

  6. IDUA(-/-) mice from adolescence to maturity, exhibited locomotor and anxiety-like compulsive behaviors, spatial learning and memory, visual recognition and short-term non-associative memory retention.

IDUA Antigen Profile

Protein Summary

This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).

Gene names and symbols associated with IDUA

  • iduronidase, alpha-L- (idua) antibody
  • iduronidase, alpha-L- (IDUA) antibody
  • fibroblast growth factor receptor-like 1a (fgfrl1a) antibody
  • fibroblast growth factor receptor-like 1 (FGFRL1) antibody
  • alpha-l-iduronidase (AaeL_AAEL004402) antibody
  • alpha-L-iduronidase (LOC100231378) antibody
  • alpha-L-iduronidase (Idua) antibody
  • iduronidase, alpha-L- (Idua) antibody
  • 6030426D08 antibody
  • alpha-L-iduronidase antibody
  • fgfrl1 antibody
  • IDA antibody
  • IDUA antibody
  • MGC80842 antibody
  • MPS1 antibody
  • si:ch211-12e13.9 antibody
  • zgc:64084 antibody

Protein level used designations for IDUA

iduronidase, alpha-L- , alpha-L-iduronidase , fibroblast growth factor receptor-like 1 , alpha-l-iduronidase

GENE ID SPECIES
446866 Xenopus laevis
511050 Bos taurus
567720 Danio rerio
100146682 Equus caballus
100560915 Anolis carolinensis
393347 Danio rerio
532327 Bos taurus
5564727 Aedes aegypti
100231378 Taeniopygia guttata
360904 Rattus norvegicus
100505382 Canis lupus familiaris
3425 Homo sapiens
15932 Mus musculus
427294 Gallus gallus
Selected quality suppliers for anti-IDUA (IDUA) Antibodies
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