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IER5 encodes a protein that is similar to other immediate early response proteins. Additionally we are shipping IER5 Proteins (4) and IER5 Kits (1) and many more products for this protein.
Showing 10 out of 71 products:
Human Polyclonal IER5 Primary Antibody for ELISA, WB - ABIN252909
Cirelli, Tononi: Gene expression in the brain across the sleep-waking cycle. in Brain research 2001
Human Polyclonal IER5 Primary Antibody for ICC, IF - ABIN4321047
Liu, Tian, Zhao, He, Li, Li, Yu, Ding, Zhou, Wu: IER5 as a promising predictive marker promotes irradiation-induced apoptosis in cervical cancer tissues from patients undergoing chemoradiotherapy. in Oncotarget 2017
Cow (Bovine) Polyclonal IER5 Primary Antibody for WB - ABIN2786983
Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006
Show all 2 Pubmed References
Authors propose the GCF (show GUCY2F Antibodies) regulated transcriptional activity, at least in part, contributed to the upregulation of IER5 on radiation in HepG2 cells. The present findings provide insights into understanding the regulatory mechanisms of IER5.
These results reveal the existence of a novel IER5-mediated cancer regulation pathway that is responsible for the activation of HSF1 (show HSF1 Antibodies) observed in various cancers.
IER5 functions as a positive feedback regulator of HSF1 (show HSF1 Antibodies) and that this process involves PP2A (show PPP2R4 Antibodies)/B55 (show MINK1 Antibodies) and HSF1 (show HSF1 Antibodies) dephosphorylation.
These observations suggest that HSF1 (show HSF1 Antibodies)-mediated IER5 expression is involved in the expression of chaperone genes and in recovery from thermal stress.
Transcriptional repression mediated by IER5 regulates Cdc25B (show CDC25B Antibodies) expression levels via the release of NF-YB (show NFYB Antibodies) and p300 (show EP300 Antibodies) in acute myeloid leukemia (show BCL11A Antibodies).
the early radiation-induced expression of IER5 affects radiosensitivity via disturbing radiation-induced cell cycle checkpoints
Studies in rat found higher mRNA levels after waking and sleep deprivation for immediate early (show JUN Antibodies) genes/transcription factors such as IER5
This gene encodes a protein that is similar to other immediate early response proteins. In the mouse, a similar gene may play an important role in mediating the cellular response to mitogenic signals. Studies in rats found the expression of a similar gene to be increased after waking and sleep deprivation.
immediate early response gene 5 protein
, immediately early response
, immediate early response 5