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Immune Receptor Expressed On Myeloid Cells 1 Proteins (IREM1)

CD300LF is an inhibitory receptor of the Ig superfamily expressed on myeloid cells. Additionally we are shipping Immune Receptor Expressed On Myeloid Cells 1 Antibodies (42) and Immune Receptor Expressed On Myeloid Cells 1 Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IREM1 246746 Q6SJQ7
IREM1 287818 Q566E6
IREM1 146722 Q8TDQ1
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Top Immune Receptor Expressed On Myeloid Cells 1 Proteins at antibodies-online.com

Showing 9 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 11 to 13 Days
$686.40
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Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,370.50
Details
HOST_Human Cells Human Fc Tag   50 μg Log in to see 16 Days
$250.80
Details

IREM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
, ,
Rat (Rattus)

Human , , ,
, ,

More Proteins for Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Interaction Partners

Mouse (Murine) Immune Receptor Expressed On Myeloid Cells 1 (IREM1) interaction partners

  1. CD300f is implicated in Wallerian degeneration and nerve regeneration by modulating both the influx and phenotype of macrophages

  2. Y276 phosphorylation is necessary for enhanced CD300f-mediated phagocytosis through the recruitment of the p85alpha regulatory subunit of phosphatidylinositol-3-kinase

  3. data highlight a previously unidentified role for CD300f in IL-4Ralpha-induced immune cell responses

  4. CMRF35-like molecule 1 (CLM-1) regulates eosinophil homeostasis by suppressing cellular chemotaxis.

  5. Several extracellular lipids (including ceramide) and lipoproteins were possible ligands for LMIR3.

  6. We conclude that expression of CD300f conveys additional capacity to recognize phosphatidylserine to myeloid cells.

  7. CLM-1 as a negative regulator of myeloid effector cells in autoimmune demyelination.

  8. DIgR2 is a functionally inhibitory receptor and can mediate negative signaling to regulate DC-initiated antigen-specific T-cell responses.

  9. the innate immune system is at least in part regulated by the qualitative and quantitative balance of the paired receptors LMIR3 and LMIR4 (show CD300LD Proteins)

  10. These results indicate that CD300LF mediates caspase (show CASP3 Proteins) and endoplasmic reticulum stress-independent cell death by a novel mechanism.

Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) interaction partners

  1. findings suggest that two rare heterozygous truncating variations (RPS24 (show RPS24 Proteins) Q191X and CD300LF P261fsX266) are risk candidates for autism spectrum disorder.

  2. CD300 molecules are all expressed by DC; CD300b (show TREM5 Proteins), d, e and f are restricted to different subpopulations of the myeloid DC lineage. They have been shown to regulate DC function both in vitro and in vivo.

  3. The data suggest that the neuroprotective role of CD300f would be the result of a complex network of cell interactions.

  4. peptides containing ITIM-like sequences of IREM-1 (CD300F) differentially regulate MyD88 (show MYD88 Proteins) and TRIF (show TRIM69 Proteins)-mediated TLR signalling

  5. CD300f blocked the activation of cells induced by all TLR ligands

  6. Data indicate that CD300F is an active regulator of TLR-mediated macrophage activation through association with SHP-1 (show PTPN6 Proteins) involving MyD88 (show MYD88 Proteins) and/or TRIF (show TRIM69 Proteins).

  7. Findings indicate that IREM-1 exerted its inhibitory effect on BAFF-medicated signalling through ITIM-mediated regulation of ERK activities in THP-1 cells.

  8. IgSF13 was identified from dendritic cells; preferentially expressed in myelo-monocytic cells, including monocytes, monocyte-derived DC and monocyte-related cell lines; may be involved in the negative regulation of specific leukocyte population [IgSF13]

  9. a novel inhibitory receptor of the Ig superfamily in myeloid cells. (IREM-1 = immune receptor expressed on myeloid cells-1)

  10. reveal a putative functional duality of the IREM-1 myeloid cell receptor

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Protein Profile

Protein Summary

CD300LF is an inhibitory receptor of the Ig superfamily expressed on myeloid cells. It mediates negative regulatory signals by recruiting SHP1 (PTPN6\; MIM 176883) or SHIP (INPP5D\; MIM 601582) (Sui et al., 2004

Gene names and symbols associated with IREM1

  • CD300 antigen like family member F (Cd300lf)
  • Cd300 molecule-like family member F (Cd300lf)
  • CD300 molecule-like family member f (CD300LF)
  • CD300f protein
  • CLIM1 protein
  • CLM-1 protein
  • CLM1 protein
  • Digr2 protein
  • F730004D16Rik protein
  • IgSF13 protein
  • IREM-1 protein
  • IREM1 protein
  • LMIR3 protein
  • NKIR protein
  • Pigr3 protein
  • RGD1309733 protein

Protein level used designations for IREM1

CD300 antigen-like family member F , CMRF-35-like molecule 1 , CMRF35-like molecule 1 , DC-derived Ig-like receptor 2 , MAIR-5 , MAIR-V , leukocyte mono-Ig-like receptor 3 , myeloid-associated immunoglobulin-like receptor 5 , CD300 antigen like family member F , CLM-1 , CD300 molecule like family member f , NK inhibitory receptor , immune receptor expressed on myeloid cells 1 , immunoglobin superfamily member 13 , immunoglobulin superfamily member 13 , inhibitory receptor IREM1

GENE ID SPECIES
246746 Mus musculus
287818 Rattus norvegicus
146722 Homo sapiens
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