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anti-Immunoglobulin Superfamily, Member 8 (IGSF8) Antibodies

IGSF8 encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Additionally we are shipping IGSF8 Proteins (12) and IGSF8 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IGSF8 93185 Q969P0
IGSF8 140559 Q8R366
IGSF8 304979  
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Top anti-IGSF8 Antibodies at antibodies-online.com

Showing 10 out of 63 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated IHC (p), WB IGSF8 Antibody (Center) (ABIN656323) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded (FFPE) human kidney tissue using CD316 / IGSF8 Antibody , followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IGSF8 antibody for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis in mouse cerebellum tissue lysates (35ug/lane) using Cd316 / IGSF8 Antibody . This demonstrates the IGSF8 antibody detected the IGSF8 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-IGSF8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 721_B cell lysate WB Suggested Anti-IGSF8  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control:.21_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated IF, WB 100 μL Log in to see 7 to 8 Days
$434.50
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemistry: CD316/IGSF8 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Brain, Cortex. Immunohistochemistry: CD316/IGSF8 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Kidney. 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged IGSF8 is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-IGSF8 antibody  ABIN960784 IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-IGSF8 antibody  ABIN960784 IHC staining of human brain, putamen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit PE IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

IGSF8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-IGSF8 Antibodies

  1. Human Polyclonal IGSF8 Primary Antibody for EIA, IHC (p) - ABIN951296 : Kolesnikova, Kazarov, Lemieux, Lafleur, Kesari, Kung, Hemler: Glioblastoma inhibition by cell surface immunoglobulin protein EWI-2, in vitro and in vivo. in Neoplasia (New York, N.Y.) 2008 (PubMed)
    Show all 3 references for ABIN951296

  2. Mouse (Murine) Polyclonal IGSF8 Primary Antibody for IHC (p), WB - ABIN656323 : Yang, Kovalenko, Kolesnikova, Andzelm, Rubinstein, Strominger, Hemler: Contrasting effects of EWI proteins, integrins, and protein palmitoylation on cell surface CD9 organization. in The Journal of biological chemistry 2006 (PubMed)
    Show all 2 references for ABIN656323

More Antibodies against IGSF8 Interaction Partners

Human Immunoglobulin Superfamily, Member 8 (IGSF8) interaction partners

  1. EWI-2 negatively regulates TGF-beta (show TGFB1 Antibodies) signaling and its downstream events including cytostasis (in vitro and in vivo), EMT (show ITK Antibodies)-like changes, cell migration, CD271 (show NGFR Antibodies)-dependent invasion, and lung metastasis (in vivo).

  2. Authors demonstrated that EWI-2wint promotes CD81 (show CD81 Antibodies) clustering and confinement in CD81 (show CD81 Antibodies)-enriched areas.

  3. The EWI-2/alpha-actinin complex is involved in regulation of the actin cytoskeleton at T cell immune and virological synapses, providing a link between membrane microdomains and the formation of polarized membrane structures involved in T cell recognition.

  4. analysis of interacting regions of CD81 (show CD81 Antibodies) and two of its partners, EWI-2 and EWI-2wint, and their effect on hepatitis C virus infection

  5. EWI2/PGRL associates with the metastasis suppressor KAI1/CD82 (show CD82 Antibodies) and inhibits the migration of prostate cancer cells.

  6. EWI-2-dependent reorganization of alpha4beta1-CD81 (show CD81 Antibodies) complexes on the cell surface is responsible for EWI-2 effects on integrin-dependent morphology and motility functions

  7. EWI proteins EWI-2 and EWI-F (show PTGFRN Antibodies), alpha3beta1 and alpha6beta4 integrins, and protein palmitoylation have contrasting effects on cell surface CD9 (show CD9 Antibodies) organization

  8. EWI-2 and EWI-F (show PTGFRN Antibodies) link the tetraspanin web to the actin cytoskeleton through their direct association with ezrin-radixin-moesin (show MSN Antibodies) proteins

  9. Important functions of recently activated dendritic cells are thus critically modulated by the newly discovered HSPA8 (show HSPA8 Antibodies)-EWI-2 interaction.

  10. CD81 (show CD81 Antibodies) partner EWI-2wint inhibits hepatitis C virus entry [EWI-2wint]

Mouse (Murine) Immunoglobulin Superfamily, Member 8 (IGSF8) interaction partners

  1. IgSF8 is present in developing olfactory sensory neuron synapses, and it interacts with Tspan CD9 (show CD9 Antibodies).

  2. Igsf8-deficient eggs retain the normal level and localization of CD9 (show CD9 Antibodies), resulting in normal microvilli formation indicating that IGSF8 is dispensable in fertility.

  3. This study showed that the EWI2 cytoplasmic tail actively engages with the cell membrane via phosphatidylinositol phosphate binding and palmitoylation.

  4. Igsf8 is first expressed at E9.5 in a ventral domain of the neural tube, with dorsal expression apparent at E10.5.. From E11.5, Igsf8 occurs at the edge of the ventricular zone, in postmitotic neuroblasts, and in sensory ganglia.

  5. EWI-2 and EWI-F (show PTGFRN Antibodies) link the tetraspanin web to the actin cytoskeleton through their direct association with ezrin-radixin-moesin (show MSN Antibodies) proteins

  6. Report that the expression level of EWI-2 on the Cd9 (show CD9 Antibodies)(-/-) oocyte surface is <10% of the wild-type level. Hence, the severe reduction in EWI-2 activity may be responsible for the loss of fusion ability.

  7. Immunoglobulin superfamily member (show CDON Antibodies) IgSF8 (EWI-2) and CD9 (show CD9 Antibodies) in fertilisation: evidence of distinct functions for CD9 (show CD9 Antibodies) and a CD9 (show CD9 Antibodies)-associated protein in mammalian sperm-egg interaction.

IGSF8 Antigen Profile

Protein Summary

This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein.

Gene names and symbols associated with IGSF8

  • zgc:77222 (zgc:77222) antibody
  • immunoglobulin superfamily, member 8 (IGSF8) antibody
  • immunoglobulin superfamily, member 8 (LOC100338663) antibody
  • immunoglobulin superfamily, member 8 (Igsf8) antibody
  • AA033172 antibody
  • AU041109 antibody
  • CD81P3 antibody
  • CD316 antibody
  • ESTM34 antibody
  • EWI-2 antibody
  • EWI2 antibody
  • IGSF8 antibody
  • KCT-4 antibody
  • LIR-D1 antibody
  • MGC77222 antibody
  • MGC151661 antibody
  • PGRL antibody
  • R75384 antibody

Protein level used designations for IGSF8

immunoglobulin superfamily member 8 , immunoglobulin superfamily, member 8 , immunoglobulin superfamily member 8-like , CD81 partner 3 , glu-Trp-Ile EWI motif-containing protein 2 , keratinocytes-associated transmembrane protein 4 , prostaglandin regulatory-like protein , PG regulatory-like protein , keratinocyte-associated transmembrane protein 4

GENE ID SPECIES
404631 Danio rerio
469549 Pan troglodytes
519266 Bos taurus
100058209 Equus caballus
100154024 Sus scrofa
100338663 Oryctolagus cuniculus
100441861 Pongo abelii
100595459 Nomascus leucogenys
93185 Homo sapiens
140559 Mus musculus
304979 Rattus norvegicus
Selected quality suppliers for anti-IGSF8 (IGSF8) Antibodies
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