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Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) ELISA Kits

The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locu. Additionally we are shipping Immunoglobulin lambda-Like Polypeptide 1 Antibodies (84) and Immunoglobulin lambda-Like Polypeptide 1 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat IGLL1 IGLL1 100360919  
Anti-Human IGLL1 IGLL1 3543 P15814
Anti-Mouse IGLL1 IGLL1 16136 P20764
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More ELISA Kits for Immunoglobulin lambda-Like Polypeptide 1 Interaction Partners

Human Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) interaction partners

  1. Hhydrophobic residues from the lambda5-UR is crucial for the interaction with GAL1 (show LGALS1 ELISA Kits) and for pre-BCR (show BCR ELISA Kits) clustering.

Mouse (Murine) Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) interaction partners

  1. Data show no autoantibody production was detectable in surrogate light chain (SLC) components VpreB/CD179a and lambda5/CD179b transgenic mice.

  2. VpreB probes the fitness of newly generated VH domains of IgH chains for later pairing with IgL chains, and its non-Ig part fixes the preBCRs on the surface.

  3. Mice triply deficient for VpreB2 show B cell developmental defects but functional allelic exclusion of the IgH locus.

  4. Data demonstrate that the pre-B-cell receptor is essential for monoallelic silencing of VpreB and lambda5 at the large pre-BII (show CACNA1E ELISA Kits)-cell stage.

Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) Antigen Profile

Antigen Summary

The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with IGLL1

  • immunoglobulin lambda-like polypeptide 1 (IGLL1) antibody
  • Immunoglobulin lambda-like polypeptide 1-like (LOC100360919) antibody
  • immunoglobulin lambda-like polypeptide 1 (Igll1) antibody
  • pre-B lymphocyte gene 2 (Vpreb2) antibody
  • 14.1 antibody
  • AGM2 antibody
  • BB139905 antibody
  • CD179b antibody
  • Igl-5 antibody
  • IGL1 antibody
  • IGL5 antibody
  • IGLJ14.1 antibody
  • Igll antibody
  • Igll1 antibody
  • IGLV antibody
  • IGO antibody
  • IGVPB antibody
  • Lambda5 antibody
  • MGC151892 antibody
  • Vpreb-2 antibody
  • VpreB1 antibody
  • VPREB2 antibody

Protein level used designations for IGLL1

Ig lambda chain V-1 region , Ig light chain variable region , immunoglobulin lambda-like polypeptide 1 , Lambda5 , Immunoglobulin lambda-like polypeptide 1-like , CD179 antigen-like family member B , CD179b antigen , Pre-B lymphocyte-specific protein-2 , ig lambda-5 , immunoglobulin omega polypeptide chain , immunoglobulin-related 14.1 protein , immunoglobulin-related protein 14.1 , lambda5 , immunoglobulin lambda chain 5 , lambda 5 , Lambda 5 , immunoglobulin omega chain

GENE ID SPECIES
416928 Gallus gallus
720135 Macaca mulatta
789205 Bos taurus
100008913 Oryctolagus cuniculus
100360919 Rattus norvegicus
3543 Homo sapiens
16136 Mus musculus
22363 Mus musculus
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