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Immunoglobulin lambda-Like Polypeptide 1 Proteins (IGLL1)

The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. Additionally we are shipping Immunoglobulin lambda-Like Polypeptide 1 Antibodies (61) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat IGLL1 IGLL1 100360919  
IGLL1 3543 P15814
IGLL1 16136 P20764
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Top Immunoglobulin lambda-Like Polypeptide 1 Proteins at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$792.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$862.40
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,030.69
Details

IGLL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine)
,

Top referenced Immunoglobulin lambda-Like Polypeptide 1 Proteins

  1. Human IGLL1 Protein expressed in Escherichia coli (E. coli) - ABIN1098784 : Bankovich, Raunser, Juo, Walz, Davis, Garcia: Structural insight into pre-B cell receptor function. in Science (New York, N.Y.) 2007 (PubMed)
    Show all 2 references for ABIN1098784

More Proteins for Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) Interaction Partners

Human Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) interaction partners

  1. Hhydrophobic residues from the lambda5-UR is crucial for the interaction with GAL1 (show LGALS1 Proteins) and for pre-BCR (show BCR Proteins) clustering.

Mouse (Murine) Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) interaction partners

  1. Data show no autoantibody production was detectable in surrogate light chain (SLC (show CCL21A Proteins)) components VpreB/CD179a (show VPREB1 Proteins) and lambda5/CD179b transgenic mice.

  2. Mice triply deficient for VpreB2 show B cell developmental defects but functional allelic exclusion of the IgH locus.

  3. Data demonstrate that the pre-B-cell receptor is essential for monoallelic silencing of VpreB (show VPREB1 Proteins) and lambda5 at the large pre-BII (show CACNA1E Proteins)-cell stage.

Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) Protein Profile

Protein Summary

The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with IGLL1

  • immunoglobulin lambda-like polypeptide 1 (IGLL1)
  • Immunoglobulin lambda-like polypeptide 1-like (LOC100360919)
  • immunoglobulin lambda-like polypeptide 1 (Igll1)
  • pre-B lymphocyte gene 2 (Vpreb2)
  • 14.1 protein
  • AGM2 protein
  • BB139905 protein
  • CD179b protein
  • Igl-5 protein
  • IGL1 protein
  • IGL5 protein
  • IGLJ14.1 protein
  • Igll protein
  • Igll1 protein
  • IGLV protein
  • IGO protein
  • IGVPB protein
  • Lambda5 protein
  • MGC151892 protein
  • Vpreb-2 protein
  • VpreB1 protein
  • VPREB2 protein

Protein level used designations for IGLL1

Ig lambda chain V-1 region , Ig light chain variable region , immunoglobulin lambda-like polypeptide 1 , Lambda5 , Immunoglobulin lambda-like polypeptide 1-like , CD179 antigen-like family member B , CD179b antigen , Pre-B lymphocyte-specific protein-2 , ig lambda-5 , immunoglobulin omega polypeptide chain , immunoglobulin-related 14.1 protein , immunoglobulin-related protein 14.1 , lambda5 , immunoglobulin lambda chain 5 , lambda 5 , Lambda 5 , immunoglobulin omega chain

GENE ID SPECIES
416928 Gallus gallus
720135 Macaca mulatta
789205 Bos taurus
100008913 Oryctolagus cuniculus
100360919 Rattus norvegicus
3543 Homo sapiens
16136 Mus musculus
22363 Mus musculus
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