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The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. Additionally we are shipping IPO7 Proteins (3) and many more products for this protein.
Showing 10 out of 73 products:
Human Polyclonal IPO7 Primary Antibody for IHC (p), WB - ABIN651626
Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006
Show all 4 references for ABIN651626
Human Polyclonal IPO7 Primary Antibody for ELISA, WB - ABIN184802
Görlich, Dabrowski, Bischoff, Kutay, Bork, Hartmann, Prehn, Izaurralde: A novel class of RanGTP binding proteins. in The Journal of cell biology 1997
Show all 2 references for ABIN184802
Human Monoclonal IPO7 Primary Antibody for ELISA, WB - ABIN523936
Plotnikov, Chuderland, Karamansha, Livnah, Seger: Nuclear extracellular signal-regulated kinase 1 and 2 translocation is mediated by casein kinase 2 and accelerated by autophosphorylation. in Molecular and cellular biology 2011
Depletion of IPO7 by IPO7 siRNA reduced nuclear accumulation of GLI1 (show GLI1 Antibodies). In addition, FOXM1 (show FOXM1 Antibodies) induced nuclear import of GLI1 (show GLI1 Antibodies) by promoting IPO7 expression.
Importin 7 as a soluble nuclear transport factor that is required for efficient import of the protein component of human telomerase.
Importin 7 contributes to the regulation of androgen receptor (show AR Antibodies) import by restraining import until androgen is detected in the cytoplasm.
imp7 is a part of an intrinsic pathway that promotes nuclear import of exogenous and endogenous DNA in mammalian cells.
Importin 7 (IPO7)is regulated positively by c-Myc (show MYC Antibodies) and negatively by p53 (show TP53 Antibodies).
essential for Egr-1 (show EGR1 Antibodies) nuclear translocation
Data show that ARHI (show DIRAS3 Antibodies) could compete for Ran-importin (show KPNA4 Antibodies) binding and induce disruption of importin (show KPNA4 Antibodies)-binding to cargo proteins, including STAT3 (show STAT3 Antibodies).
role of IMP7 in nuclear transport of H1 histones
Nuclear import of HIV-1 intracellular reverse transcription is mediated by IPO7.
These results identify EZI as a novel cargo protein for importin-7 and demonstrate a nucleocytoplasmic shuttling mechanism that is mediated by importin-7-dependent nuclear localization and CRM1 (show XPO1 Antibodies)-independent nuclear export.
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.
, RAN binding protein 7
, importin 7
, RAN-binding protein 7
, ran-binding protein 7