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Importin 7 Proteins (IPO7)

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. Additionally we are shipping IPO7 Antibodies (68) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IPO7 10527 O95373
IPO7 233726 Q9EPL8
Rat IPO7 IPO7 308939  
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Top IPO7 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

IPO7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Importin 7 (IPO7) Interaction Partners

Human Importin 7 (IPO7) interaction partners

  1. Depletion of IPO7 by IPO7 siRNA reduced nuclear accumulation of GLI1 (show GLI1 Proteins). In addition, FOXM1 (show FOXM1 Proteins) induced nuclear import of GLI1 (show GLI1 Proteins) by promoting IPO7 expression.

  2. Importin 7 as a soluble nuclear transport factor that is required for efficient import of the protein component of human telomerase.

  3. Importin 7 contributes to the regulation of androgen receptor (show AR Proteins) import by restraining import until androgen is detected in the cytoplasm.

  4. imp7 is a part of an intrinsic pathway that promotes nuclear import of exogenous and endogenous DNA in mammalian cells.

  5. Importin 7 (IPO7)is regulated positively by c-Myc (show MYC Proteins) and negatively by p53 (show TP53 Proteins).

  6. essential for Egr-1 (show EGR1 Proteins) nuclear translocation

  7. Data show that ARHI (show DIRAS3 Proteins) could compete for Ran-importin (show KPNA4 Proteins) binding and induce disruption of importin (show KPNA4 Proteins)-binding to cargo proteins, including STAT3 (show STAT3 Proteins).

  8. role of IMP7 in nuclear transport of H1 histones

  9. Nuclear import of HIV-1 intracellular reverse transcription is mediated by IPO7.

  10. These results identify EZI as a novel cargo protein for importin-7 and demonstrate a nucleocytoplasmic shuttling mechanism that is mediated by importin-7-dependent nuclear localization and CRM1-independent nuclear export.

IPO7 Protein Profile

Protein Summary

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.

Gene names and symbols associated with Importin 7 Proteins (IPO7)

  • importin 7 (ipo7)
  • importin 7 (IPO7)
  • importin-7 (CpipJ_CPIJ002096)
  • importin-7 (PTRG_08544)
  • importin-7 (SJAG_03693)
  • importin-7 (NAEGRDRAFT_71372)
  • importin-7 (VDBG_01971)
  • importin-7 (MGYG_08162)
  • importin-7 (Tsp_01943)
  • importin-7 (Tsp_01946)
  • importin 7 (Ipo7)
  • A330055O14Rik protein
  • C330016G14 protein
  • fb33d09 protein
  • Imp7 protein
  • Ranbp7 protein
  • wu:fb33d09 protein
  • zgc:66425 protein
  • zgc:76878 protein

Protein level used designations for Importin 7 Proteins (IPO7)

importin-7 , RAN binding protein 7 , importin 7 , RAN-binding protein 7 , ran-binding protein 7

GENE ID SPECIES
321739 Danio rerio
379321 Xenopus laevis
513707 Bos taurus
748139 Pan troglodytes
6032827 Culex quinquefasciatus
6346830 Pyrenophora tritici-repentis Pt-1C-BFP
7052209 Schizosaccharomyces japonicus yFS275
8864455 Naegleria gruberi strain NEG-M
9535573 Verticillium alfalfae VaMs.102
10025220 Arthroderma gypseum CBS 118893
10907156 Trichinella spiralis
10907170 Trichinella spiralis
100101664 Xenopus (Silurana) tropicalis
10527 Homo sapiens
233726 Mus musculus
308939 Rattus norvegicus
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