anti-Importin 8 (IPO8) Antibodies

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. Additionally we are shipping Importin 8 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IPO8 10526 O15397
IPO8 320727 Q7TMY7
IPO8    
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Top anti-Importin 8 Antibodies at antibodies-online.com

Showing 10 out of 34 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-IPO8 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Kidney 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC, ELISA, WB   100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Goat Un-conjugated IHC (p), IHC, ELISA Immunohistochemistry-Paraffin: Importin-8 Antibody [ABIN249599] - Staining of Human Tonsil. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining. Similar results were obtained after antigen retrieval at pH9. (4ug/ml) 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated ICC, IF, SimWes, WB Western Blot: Importin-8 Antibody [NBP2-24751] - Analysis of Importin-8 in HeLa lysate in the 1) absence and 2) presence of immunizing peptide using Importin-8 antibody at 1 ug/ml. Simple Western: Importin-8 Antibody [NBP2-24751] - Simple Western lane view shows a specific band for Importin-8 in 0.5 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Goat Un-conjugated ELISA 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Un-conjugated ICC, IF, WB 100 μg Log in to see 7 to 9 Days
$507.83
Details
Cow Goat Un-conjugated EIA, IHC (p)   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$240.00
Details
Mouse Rabbit Un-conjugated ICC, IHC, IP, WB 100 μg Log in to see 15 to 18 Days
$324.00
Details
Human Rabbit Un-conjugated WB Western Blot: Importin-8 Antibody [ABIN4090904] - Whole cell lysate from HeLa (5, 15 and 50 ug) and 293T (T; 50 ug) cells. Antibody used at for WB at 0.4 ug/ml. 100 μL Log in to see 7 to 9 Days
$486.94
Details

IPO8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Dog (Canine) , ,
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Top referenced anti-Importin 8 Antibodies

  1. Human Polyclonal Importin 8 Primary Antibody for ICC, IF - ABIN4325788 : Wu, Wang, Young, Lai, Li: Proteome-wide identification of novel binding partners to the oncogenic fusion gene protein, NPM-ALK, using tandem affinity purification and mass spectrometry. in The American journal of pathology 2009 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal Importin 8 Primary Antibody for IHC (p), IHC - ABIN249599 : Görlich, Dabrowski, Bischoff, Kutay, Bork, Hartmann, Prehn, Izaurralde: A novel class of RanGTP binding proteins. in The Journal of cell biology 1997 (PubMed)

More Antibodies against Importin 8 Interaction Partners

Human Importin 8 (IPO8) interaction partners

  1. the findings of the present study provided novel insights into the control of IPO8 transcription, and may enhance understanding regarding RUNX2 (show RUNX2 Antibodies) regulatory mechanisms in osteoblast differentiation, bone development, and degenerative bone disease.

  2. Our studies also suggest that nuclear entry is important for the prooncogenic activity of eIF4E (show EIF4E Antibodies), at least in this context. These findings position nuclear trafficking of eIF4E (show EIF4E Antibodies) as a critical step in its regulation and position the importin 8-eIF4E (show EIF4E Antibodies) complex as a novel therapeutic target.

  3. importin alpha8 functions as a cNLS receptor with distinct cargo specificity, and that heterodimerization by importin alpha8 is a novel regulatory mode of cNLS binding, in addition to the autoinhibitory regulation by the importin beta (show KPNB1 Antibodies) binding domain.

  4. Knockdown of IPO8 reduced the amount of nuclear p65 (show GORASP1 Antibodies) following TNF (show TNF Antibodies) stimulation. IPO8 binding to p65 (show GORASP1 Antibodies) is NLS (show ALDH1A2 Antibodies) independent.

  5. TGF-beta (show TGFB1 Antibodies)-induced and basal state spontaneous nuclear import of Smad4 (show SMAD4 Antibodies) require importin 7 (show IPO7 Antibodies) and 8.

  6. IPO8 is the most accurate reference gene for clinical lung specimens.

  7. Study provides evidence that Imp8 is required for cytoplasmic miRNA-guided gene silencing and affects nuclear localization of Ago proteins.

Mouse (Murine) Importin 8 (IPO8) interaction partners

  1. Importin 8 plays a critical role in mediating the cytoplasm-to-nucleus transport of mature miRNAs. IPO8-mediated nuclear transport of mature miRNAs is also dependent on the association of IPO8 with the Argonaute 2 (show EIF2C2 Antibodies) complex.

Importin 8 (IPO8) Antigen Profile

Protein Summary

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Importin 8 (IPO8) Antibodies

  • importin 8 (IPO8) antibody
  • importin 8 (ipo8) antibody
  • importin 8 (Ipo8) antibody
  • 6230418K12Rik antibody
  • Abcc10 antibody
  • C130009K11Rik antibody
  • IPO8 antibody
  • MRP7 antibody
  • OM-1 antibody
  • Om1 antibody
  • Ranbp8 antibody
  • si:ch211-116i17.1 antibody

Protein level used designations for anti-Importin 8 (IPO8) Antibodies

importin 8 , importin-8 , RAN binding protein 8 , imp8 , ran-binding protein 8 , ATP-binding cassette, sub-family C (CFTR/MRP), member 10 , oocyte maturation 1

GENE ID SPECIES
418142 Gallus gallus
473395 Pan troglodytes
523408 Bos taurus
555520 Danio rerio
612863 Canis lupus familiaris
10526 Homo sapiens
320727 Mus musculus
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