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INADL encodes a protein with multiple PDZ domains. Additionally we are shipping InaD-Like (Drosophila) Antibodies (48) and and many more products for this protein.
Results indicate a role for Yes associated protein (YAP (show YAP1 ELISA Kits)), which is inhibited by the Hippo pathway, in the cytokinesis machinery during mitosis through interaction with the polarity protein PATJ.
Data show that PATJ regulates the spatial concentration of several tight junction components at the border between the apical and lateral domains in Caco-2 cells.
PATJ controls directional migration by regulating the localization of aPKC and Par3 (show F2RL2 ELISA Kits) to the leading edge of epithelial cells.
We have identified the tight junction-associated multi-PDZ protein PATJ (PALS1 (show MPP5 ELISA Kits)-associated TJ protein) as a novel binding partner and degradation target of high-risk types 16 and 18 E6.
the directional migration of capillaries in the embryo is governed by the Amot:Patj/Mupp1 (show MPDZ ELISA Kits):Syx (show PLEKHG5 ELISA Kits) signaling that controls local GTPase (show RACGAP1 ELISA Kits) activity
Data show taht channel-interacting PDZ protein, 'CIPP', interacts with proteins involved in cytoskeletal dynamics.
Results suggest that signaling mediated by Pals1 (show MPP5 ELISA Kits), which has a higher affinity for Patj than for MUPP1 (show MPDZ ELISA Kits) and is involved in the activation of the Par6 (show PARD6A ELISA Kits)-aPKC complex, is of principal importance for the function of Patj in epithelial cells.
Signalling molecules and effectors can be integrated into a functional network by the scaffold organizer protein PATJ via its multiple PDZ domains.
analysis of structures of tetrameric L27 (show RPL27A ELISA Kits) domain complexes formed by mLin-2 (show CASK ELISA Kits)/mLin-7 (show LIN7A ELISA Kits) and Patj/Pals1 (show MPP5 ELISA Kits) scaffold proteins
Data show that MUPP1 (show MPDZ ELISA Kits) interacts with angiomotin (Amot (show AMOT ELISA Kits)), JEAP (show AMOTL1 ELISA Kits)/Amot (show AMOT ELISA Kits)-like 1 and MASCOT/Amot (show AMOT ELISA Kits)-like 2, and that all the Amot (show AMOT ELISA Kits)/JEAP (show AMOTL1 ELISA Kits) family proteins also interacted with Patj, a close relative of MUPP1 (show MPDZ ELISA Kits).
Data show taht channel-interacting PDZ protein, 'CIPP', interacts with proteins involved in cytoskeletal dynamics, in particular, with the small G-protein (show RAC2 ELISA Kits) effector IRSp53 (show BAIAP2 ELISA Kits)
This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors.
, inaD-like protein
, PALS1-associated tight junction protein
, PDZ domain protein
, channel-interacting PDZ domain protein
, inactivation no after-potential D-like protein
, protein associated to tight junctions
, channel-interacting PDZ domain-containing protein
, novel ankyrin-repeat protein
, InaD-like 2