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anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) Antibodies

IDO1 encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. Additionally we are shipping Indoleamine 2,3-Dioxygenase 1 Kits (13) and Indoleamine 2,3-Dioxygenase 1 Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IDO1 3620 P14902
IDO1 15930 P28776
IDO1 66029 Q9ERD9
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Top anti-Indoleamine 2,3-Dioxygenase 1 Antibodies at antibodies-online.com

Showing 10 out of 182 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-INDO Antibody (C-term) (ABIN389194) in 293 cell line lysates (35 µg/lane). INDO(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with INDO antibody (C-term) (ABIN389194), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Mouse Un-conjugated FACS, IP, IHC, ELISA, WB Western Blot of Mouse Anti-IDO1 Antibody. Lane 1: untreated HeLa cells. Lane 2: IFN-r treated HeLa cells. Load: 35 µg per lane. Primary antibody: IDO 1 Antibody at 1:1000 for overnight at 4°C. Secondary antibody: IRDye800™ mouse secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: 41-42 kDa, 41-42 kDa for IDO-1. Other band(s): none. 25 μL Log in to see 2 to 3 Days
$135.00
Details
Mouse Mouse Un-conjugated FACS, IHC, ELISA, WB Immunofluorescence Microscopy of Mouse anti-IDO1 Antibody. Cells: HEK293 cells. Fixation: 0.5% PFA. Expressing: mouse IDO-1 (left) and mouse IDO-2 (right). Primary antibody: IDO1 (2E2) monoclonal antibody. Antigen retrieval: not required. Secondary antibody: mouse secondary antibody at 1:10,000 for 45 min at RT. Localization: IDO-1 is located in the cytosol. Staining: IDO1 as red fluorescent signal with bis-benzimide nuclear counterstain (blue). 25 μL Log in to see 2 to 3 Days
$135.00
Details
Mouse Rabbit Un-conjugated IHC (fro), IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$489.50
Details
Human Rabbit Un-conjugated IF (cc), IF (p), IHC (p), WB Formalin-fixed and paraffin-embedded human lung carcinoma labeled with Anti-IDO Polyclonal Antibody, Unconjugated (ABIN1714836) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, FITC conjugated used at 1:200 dilution for 40 minutes at 37°C. 100 μL Log in to see 14 to 21 Days
$269.50
Details
Human Sheep Un-conjugated EIA, FACS, IF, IHC (p), WB   0.1 mg Log in to see 10 to 12 Days
$462.00
Details
Human Goat Un-conjugated IF, IHC, ELISA   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IHC (p), WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC (p), WB INDO Antibody (Center) (ABIN650713) western blot analysis in K562 cell line lysates (35 µg/lane).This demonstrates the INDO antibody detected the INDO protein (arrow). INDO Antibody (Center) (ABIN650713) western blot analysis in mouse cerebellum tissue lysates (35 µg/lane).This demonstrates the INDO antibody detected the INDO protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details

IDO1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Indoleamine 2,3-Dioxygenase 1 Antibodies

  1. Human Polyclonal IDO1 Primary Antibody for EIA, IHC (p) - ABIN357869 : Maghzal, Thomas, Hunt, Stocker: Cytochrome b5, not superoxide anion radical, is a major reductant of indoleamine 2,3-dioxygenase in human cells. in The Journal of biological chemistry 2008 (PubMed)
    Show all 2 references for ABIN357869

  2. Human Polyclonal IDO1 Primary Antibody for IHC (p), WB - ABIN389194 : Scheler, Wenzel, Tüting, Takikawa, Bieber, von Bubnoff: Indoleamine 2,3-dioxygenase (IDO): the antagonist of type I interferon-driven skin inflammation? in The American journal of pathology 2007 (PubMed)
    Show all 2 references for ABIN389194

  3. Human Polyclonal IDO1 Primary Antibody for EIA, FACS - ABIN1107630 : Grohmann, Fallarino, Puccetti: Tolerance, DCs and tryptophan: much ado about IDO. in Trends in immunology 2003 (PubMed)
    Show all 2 references for ABIN1107630

  4. Human Polyclonal IDO1 Primary Antibody for IF, IHC - ABIN185488 : Munn, Sharma, Baban, Harding, Zhang, Ron, Mellor: GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase. in Immunity 2005 (PubMed)

  5. Human Polyclonal IDO1 Primary Antibody for IF (cc), IF (p) - ABIN1714836 : Fu, Zhang, Song, Sheng, Li, Li, Song, Wang, Chu, Wei: Effect of bone marrow-derived CD11b(+)F4/80 (+) immature dendritic cells on the balance between pro-inflammatory and anti-inflammatory cytokines in DBA/1 mice with collagen-induced arthritis. in Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2014 (PubMed)

  6. Mouse (Murine) Polyclonal IDO1 Primary Antibody for IHC (fro), IHC (p) - ABIN1107631 : Hill, Pereira, Chauveau, Zagani, Remy, Tesson, Mazal, Ubillos, Brion, Asghar, Ashgar, Mashreghi, Kotsch, Moffett, Doebis, Seifert, Boczkowski, Osinaga, Anegon: Heme oxygenase-1 inhibits rat and human breast cancer cell proliferation: mutual cross inhibition with indoleamine 2,3-dioxygenase. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005 (PubMed)

  7. Mouse (Murine) Monoclonal IDO1 Primary Antibody for FACS, IHC - ABIN1043820 : Mellor, Munn: IDO expression by dendritic cells: tolerance and tryptophan catabolism. in Nature reviews. Immunology 2004 (PubMed)

More Antibodies against Indoleamine 2,3-Dioxygenase 1 Interaction Partners

Cow (Bovine) Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

  1. Differential expression of CD25 (show IL2RA Antibodies) and IDO mRNA with high and low virulence bovine viral diarrhea virus might reflect temporal differences in transcription during the immune response elicited by these viral strains.

  2. IDO may be involved in downregulating immune responses to M. avium subsp. paratuberculosis and other virulent mycobacteria, which may be an example of the pathogen harnessing host immunoregulatory pathways to aid survival.

  3. INDO participates in IFN-gama-induced death of bovine luteal cells, through a mechanism that involves degradation of tryptophan, thereby reducing tryptophan concentrations to a point insufficient to meet luteal cells needs

Rhesus Monkey Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

  1. SIV-infected macaques exhibiting progression to AIDS displayed greater expression of TGF-beta (show TGFB1 Antibodies) and indoleamine 2,3 dioxygenase in CD8 (show CD8A Antibodies)+ T cells from mesentric lymph nodes.

Human Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

  1. Results suggest Withaferin A (WA) as a valuable small ligand molecule with strong binding affinity toward indoleamine 2,3-dioxygenase (IDO).

  2. Our results imply the probability of involvement of IDO in development of tolerance process, and we presume that high IDO activity is associated with nonresponsiveness to food allergens despite allergen sensitization.

  3. IDO, through GCN2 (show EIF2AK4 Antibodies) kinase activation, downregulates the levels of TCRcomplex tchain and cMyc (show MYC Antibodies), resulting in the suppression of Tcell proliferation and a reduction in the levels of LDHA (show LDHA Antibodies) and GLS2 (show GLS2 Antibodies)

  4. ISG15 (show ISG15 Antibodies) is elevated in viremic HIV-1 patients and is associated with high TRAIL and IDO levels.

  5. IDO1 expression and activity in LC seem to be involved in the pathophysiology of EH in AD and could represent a predictive biomarker for patients with risk to develop EH and other viral complications.

  6. slows down viral replication during Hepatitis C infection; inhibits CD4 (show CD4 Antibodies)-T cells proliferation

  7. MT has potentiating effect in TGF-beta1 (show TGFB1 Antibodies)-induced EMT (show ITK Antibodies), independently of IDO. This nonimmunological effect of MT should be considered if IDO is the target to avoid immune escape in bladder cancer

  8. We conclude that autophagy, but not IDO and IFNgamma responsiveness, is dispensable for MSC's immunosuppressive properties. MSCs from CD subjects are functionally analogous to those of healthy individuals

  9. IDO expression was increased in acute phase multiple sclerosis compared to patients in stable phase.

  10. the role of IFN-lambda in IDO regulation was investigated after influenza infection of respiratory epithelial cells.

Mouse (Murine) Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

  1. Severity of sodium dodecyl sulfate-induced colitis is reduced in Ido1-deficient mice with down-regulation of TLR-MyD88 (show MYD88 Antibodies)-NF-kB transcriptional networks.

  2. IDO1 deficiency does not affect inflammation in Systemic Juvenile Idiopathic Arthritis, Secondary Hemophagocytic Lymphohistiocytosis and a T cell-triggered cytokine release model.

  3. Data indicate that indolamine-2,3-dioxygenase (IDO) and Fibroblast activation protein alpha (show FAP Antibodies) (FAPalpha) were detectable in B16 melanoma tumor-bearing mice.

  4. Increased expression of IDO in liver cell adenomas compared to the surrounding normal tissue may create a microenvironment that promotes the progression of HCC (show FAM126A Antibodies) by suppressing the proliferation of cytotoxic T lymphocytes and enhancing Tregs.

  5. Chimeric vaccine stimulation of human dendritic cell IDO1 occurs via the non-canonical NF-kappaB (show NFKB1 Antibodies) pathway.

  6. Absence of Ido1 protects against atherosclerosis through increase of Il10 (show IL10 Antibodies).

  7. the role of IFN-lambda in IDO regulation was investigated after influenza infection of respiratory epithelial cells.

  8. TNF-alpha (show TNF Antibodies) mediates stress-induced depression by upregulating indoleamine 2,3-dioxygenase in a mouse model of unpredictable chronic mild stress.

  9. Experimental hemophilic mouse models with or without functional IDO1 revealed that tryptophan metabolites, which result from IDO1 activity, prevent generation of anti-FVIII (show F8 Antibodies) antibodies.

  10. Data indicate indoleamine 23-dioxygenase 1 IDO1 induction in B cells as a negative regulatory mechanism of the T Cell-independent antigens (TI) humoral immune response.

Pig (Porcine) Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

Indoleamine 2,3-Dioxygenase 1 (IDO1) Antigen Profile

Protein Summary

This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.

Gene names and symbols associated with IDO1

  • indoleamine 2,3-dioxygenase 1 (IDO1) antibody
  • indoleamine 2,3-dioxygenase 1 (ido1) antibody
  • indoleamine 2,3-dioxygenase 1 (Ido1) antibody
  • indoleamine 2,3-dioxygenase 1-like (LOC100050681) antibody
  • cd107b antibody
  • Ido antibody
  • IDO-1 antibody
  • IDO1 antibody
  • Indo antibody

Protein level used designations for IDO1

indoleamine-pyrrole 2,3 dioxygenase , indoleamine 2,3-dioxygenase 2 , proto-IDO , putative indoleamine 2,3-dioxygenase , indoleamine 2,3-dioxygenase 1 , indolamine 2,3 dioxygenase , indole 2,3-dioxygenase , indoleamine-pyrrole 2,3-dioxygenase , IDO-1 , indoleamine 23-dioxygenase

GENE ID SPECIES
506281 Bos taurus
100037099 Xenopus laevis
100086385 Ornithorhynchus anatinus
448488 Xenopus (Silurana) tropicalis
464134 Pan troglodytes
571967 Danio rerio
574370 Macaca mulatta
100032999 Monodelphis domestica
100196903 Ovis aries
3620 Homo sapiens
15930 Mus musculus
66029 Rattus norvegicus
475574 Canis lupus familiaris
100519877 Sus scrofa
100050681 Equus caballus
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