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anti-Inducible T-Cell Co-Stimulator Ligand (ICOSLG) Antibodies

Ligand for the T-cell-specific cell surface receptor ICOS. Additionally we are shipping Inducible T-Cell Co-Stimulator Ligand Proteins (24) and Inducible T-Cell Co-Stimulator Ligand Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ICOSLG 50723 Q9JHJ8
ICOSLG 23308 O75144
ICOSLG 499415  
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Top anti-Inducible T-Cell Co-Stimulator Ligand Antibodies at antibodies-online.com

Showing 10 out of 190 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse FITC FACS 0.1 mg Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of CD275 / ICOS Ligand (C-term)  Antibody  in HL-60 cell line lysates (35ug/lane). This demonstrates the ICOSLG antibody detected the ICOSLG protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated FACS, IHC (fro) 0.1 mg Log in to see 6 to 8 Days
$308.00
Details
Human Mouse Un-conjugated WB ICOSLG monoclonal antibody (M01), clone 1E2 Western Blot analysis of ICOSLG expression in HL-60. Detection limit for recombinant GST tagged ICOSLG is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged ICOSLG is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB ICOSLG Antibody (C-term) (ABIN658792) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the ICOSLG antibody detected the ICOSLG protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ICOSLG AntibodyTitration: 1.0 µg/mL  Positive Control: ACHN Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated Func, FACS, IHC (fro) Surface staining of normal human peripheral blood cells with anti-human B7RP-1 (MIH12) PE. Appropriate isotype controls were used (open histogram). Cells in the lymphocyte population were used for analysis. 100 μg Log in to see 5 to 6 Days
$321.00
Details
Human Mouse Un-conjugated cELISA, FACS Specificity testing of GM13C1. BOSC cells were transiently transfected with an expression vector for the extracellular domain of ICOSL as well as an irrelevant protein. Expression of the constructs was tested with an anti-tag monoclonal antibody (B) 100 μg Log in to see 5 to 6 Days
$358.05
Details
Human Mouse Un-conjugated EIA, FACS, IHC (p), IP 50 μg Log in to see 6 to 8 Days
$500.50
Details

ICOSLG Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , , , ,
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Top referenced anti-Inducible T-Cell Co-Stimulator Ligand Antibodies

  1. Human Monoclonal ICOSLG Primary Antibody for WB - ABIN395495 : Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: An approach based on a genome-wide association study reveals candidate loci for narcolepsy. in Human genetics 2010 (PubMed)
    Show all 5 references for ABIN395495

  2. Human Monoclonal ICOSLG Primary Antibody for ELISA, WB - ABIN396321 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN396321

  3. Human Polyclonal ICOSLG Primary Antibody for EIA, WB - ABIN951266 : Pan, Yang, Chen, Chen, Gao, Liu, Pei, Sha, Jiang, Xu, Recker, Deng: Impact of female cigarette smoking on circulating B cells in vivo: the suppressed ICOSLG, TCF3, and VCAM1 gene functional network may inhibit normal cell function. in Immunogenetics 2010 (PubMed)
    Show all 5 references for ABIN951266

  4. Human Monoclonal ICOSLG Primary Antibody for cELISA, FACS - ABIN108723 : Richter, Hayden-Ledbetter, Irgang, Ledbetter, Westermann, Körner, Daemen, Clark, Aicher, Pezzutto: Tumor necrosis factor-alpha regulates the expression of inducible costimulator receptor ligand on CD34(+) progenitor cells during differentiation into antigen presenting cells. in The Journal of biological chemistry 2001 (PubMed)
    Show all 3 references for ABIN108723

  5. Human Polyclonal ICOSLG Primary Antibody for WB - ABIN658792 : Dubois, Trynka, Franke, Hunt, Romanos, Curtotti, Zhernakova, Heap, Adány, Aromaa, Bardella, van den Berg, Bockett, de la Concha, Dema, Fehrmann, Fernández-Arquero, Fiatal, Grandone, Green et al.: Multiple common variants for celiac disease influencing immune gene expression.... in Nature genetics 2010 (PubMed)
    Show all 3 references for ABIN658792

  6. Human Monoclonal ICOSLG Primary Antibody for Func, FACS - ABIN282425 : Carreno, Collins: The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. in Annual review of immunology 2002 (PubMed)
    Show all 2 references for ABIN282425

  7. Human Monoclonal ICOSLG Primary Antibody for FACS - ABIN317030 : Youngnak-Piboonratanakit, Tsushima, Otsuki, Igarashi, Omura, Azuma: Expression and regulation of human CD275 on endothelial cells in healthy and inflamed mucosal tissues. in Scandinavian journal of immunology 2006 (PubMed)

More Antibodies against Inducible T-Cell Co-Stimulator Ligand Interaction Partners

Mouse (Murine) Inducible T-Cell Co-Stimulator Ligand (ICOSLG) interaction partners

  1. There was a clearly positive correlation between the presence of IL-17 (show IL17A Antibodies)-producing cells and ICOS (show ICOS Antibodies) expression in ICOSL KO mice; it also showed that Th17 was involved in the pathological tissue remodeling in liver fibrosis induced by schistosomiasis.

  2. Selective ablation of ICOSL in CD11c (show ITGAX Antibodies)+ cells, but not in B cells, dramatically ameliorates kidney and lung inflammation in lupus-prone transgenic mice.

  3. ICOS-ICOS (show ICOS Antibodies)-L interaction promoted cytokine production and survival in type 2 innate lymphoid cells through STAT5 (show STAT5A Antibodies) signaling in asthma.

  4. restoring control of the T follicular helper-germinal center B-cell axis by blocking the ICOS (show ICOS Antibodies)-ICOSL pathway reduced the development of atherosclerosis and the formation of tertiary lymphoid organs.

  5. ICOSL is a molecular linkage between T-B interactional dynamics and positive selection for high-affinity bone-marrow plasma cell formation; study reveals a pathway by which follicular T-helper cells control the quality of long-lived humoral immunity

  6. the costimulatory ligand ICOS ligand (ICOSL) is selectively downregulated on the surface of B cells in an ADAM17 (show ADAM17 Antibodies)-specific manner, although it is not proteolitically processed by recombinant ADAM17 (show ADAM17 Antibodies) in vitro.

  7. The need for additional immune suppression in the intestine reflects commensal microbe-driven T-cell activation through the accessory costimulation molecules ICOSL and OX40L (show TNFSF4 Antibodies) in B7 deprived mice.

  8. the B7h-ICOS (show ICOS Antibodies) interaction may modulate the spread of cancer metastases

  9. Findings indicate the separable roles of delivery of antigens and ICOS-L by cognate B cells for follicular Th (Tfh) cell maturation and function.

  10. Data indicate that the signals provided by ICOSL-expressing B cells to Teff cells and Tfh cells are necessary for the development of arthritis.

Human Inducible T-Cell Co-Stimulator Ligand (ICOSLG) interaction partners

  1. Loss-of-function mutations in NIK (show MAP3K14 Antibodies) cause impaired ICOSL expression.

  2. ICOS-ICOS (show CTLA4 Antibodies)-L interaction promoted cytokine production and survival in type 2 innate lymphoid cells through STAT5 (show STAT5A Antibodies) signaling in asthma.

  3. Our data show that mDCs from patients with AR display impaired expression of ICOSL, and this defect licenses mDCs to promote aberrant IL-13 (show IL13 Antibodies)- and IL-5 (show IL5 Antibodies)-producing Th2 cell responses.

  4. These data suggest that rs2294020 SNP of FOXP3 (show FOXP3 Antibodies) gene and rs378299 SNP of ICOSLG gene are associated with alopecia areata and with a reduced expression of the FOXP3 (show FOXP3 Antibodies) and ICOSLG genes in alopecia patients.

  5. a critical role is described for the rs7282490 ICOSLG region polymorphism associated with immune-mediated diseases in amplifying pattern-recognition receptor initiated inflammatory signaling and cytokine secretion

  6. the B7h (show CD274 Antibodies)-ICOS (show CTLA4 Antibodies) interaction may modulate the spread of cancer metastases

  7. Findings suggest that the single nucleotide polymorphism (snp) rs4819388 in B7-H2 3'-UTR (show UTS2R Antibodies), through disrupting the regulatory role of miR (show MLXIP Antibodies)-24 on B7-H2 expression, contributes to the occurrence of gastric cancer.

  8. ICOS (show CTLA4 Antibodies)-ICOSL signaling plays a direct role in proliferation and differentiation of thyroid gland cells and may have important effects on the initiation, maintenance and exaggeration of autoimmune responses in local tissue.

  9. Results highlight an important relationship between Treg and pDC (show PNKD Antibodies) in breast tumors, and show that ICOS/ICOS (show CTLA4 Antibodies)-L interaction is a central event in immunosuppression of tumor-associated memory CD4 (show CD4 Antibodies)(+) T cells.

  10. ICOSL-expressing macrophages and mRNA levels of ICOSL were increased in the lesional skin of patients with early diffuse cutaneous systemic sclerosis.

Inducible T-Cell Co-Stimulator Ligand (ICOSLG) Antigen Profile

Protein Summary

Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion\; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co- stimulating memory T-cell function (By similarity).

Gene names and symbols associated with ICOSLG

  • inducible T-cell co-stimulator ligand (ICOSLG) antibody
  • icos ligand (Icosl) antibody
  • inducible T-cell co-stimulator ligand (Icoslg) antibody
  • AU044799 antibody
  • B7-H2 antibody
  • B7h antibody
  • B7H2 antibody
  • B7RP-1 antibody
  • B7RP1 antibody
  • BG071784 antibody
  • CD275 antibody
  • GI50 antibody
  • GL50 antibody
  • GL50-B antibody
  • ICOS-L antibody
  • Icosl antibody
  • Icoslg antibody
  • LICOS antibody
  • Ly115l antibody
  • mKIAA0653 antibody
  • RGD1562791 antibody

Protein level used designations for ICOSLG

CD80-like protein , ICOS ligand , inducible T-cell co-stimulator ligand , B7 homolog 2 , B7-like protein Gl50 , B7-related protein 1 , B7 homologue 2 , transmembrane protein B7-H2 ICOS ligand , icos ligand

GENE ID SPECIES
395968 Gallus gallus
474132 Pan troglodytes
487793 Canis lupus familiaris
507857 Bos taurus
50723 Mus musculus
23308 Homo sapiens
499415 Rattus norvegicus
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