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INHA encodes the alpha subunit of inhibins A and B protein complexes. Additionally we are shipping Inhibin alpha Antibodies (240) and Inhibin alpha Kits (60) and many more products for this protein.
Showing 10 out of 45 products:
Human Inhibin alpha Protein expressed in Escherichia coli (E. coli) - ABIN1098742
Mather, Moore, Li: Activins, inhibins, and follistatins: further thoughts on a growing family of regulators. in Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1997
Show all 2 references for ABIN1098742
The stimulation of inha expression by FSH and the potential inhibition of FSH by inhibin suggest a possible existence of a negative feedback loop between the pituitary and ovary in the zebrafish.
findings report the changes in inhibin-alpha subunit gene expression in the corpus luteum is regulated by LH; results suggest a possible multiple crosstalk of Wnt, cAMP, and SF-1 in the regulation of luteal inhibin secretion
molecular cloning of a novel inhibin alpha cDNA
The study is the first to identify an intratesticular role for inhibin/inhibin-alpha subunit, demonstrating that a threshold level of this protein is required for normal testis development and to sustain adult somatic testicular cell function.
inhibin is a broad regulatory marker in anterior pituitary cells
A novel role for GDF9 (show GDF9 Proteins) in causing reproductive defects and suppressing tumor initiation in the Inha(-/-) mouse model.
Data indicate that the inhibin-alpha promoter is activated synergistically by Wt1 (show WT1 Proteins) and Sf1 (show SF1 Proteins).
Inhibin alpha-subunit N terminus interacts with activin type IB receptor to disrupt activin signaling.
relationship between inhibin and Sertoli cell activity
These data support the role of proconvertase PCSK5 in the processing of ovarian inhibin subunits during folliculogenesis.
There are widespread alterations in the transcriptome of gonadotropin-treated Inha-/- granulosa cells, with significant changes in genes involved in extracellular matrix and cell-cell communication.
Results demonstrate that RB is not essential for Sertoli cell tumorigenesis in Inha KO mice but that loss of Inha accelerates the infertility phenotype of Rb cKO mice.
SMAD 2 is not required for mediating tumorigenic signals of activin in ovarian tumor development caused by loss of inhibin.
The Sertoli cell hormones inhibin-B and anti Mullerian hormone (show AMH Proteins) have different patterns of secretion in prepubertal cryptorchid boys.
Aberrant methylation and common genetic variation in the INHA promoter occur in human adrenocortical carcinoma and are associated with decreased INHA expression.
the correlation between placental DNAm of INHBA (show INHBA Proteins)/FN1 (show FN1 Proteins) and maternal serum INHA/FN1 (show FN1 Proteins) levels indicate that DNAm may be a useful tool to identify novel biomarkers for adverse pregnancy outcomes in some cases.
The present study did not find an association between INHA-124A>G and -16C>T and the risk of premature ovarian failure (POF (show POF1B Proteins)). For the 769G>A mutation, Asian women with the 769A allele were found to be susceptible to POF (show POF1B Proteins).
Inhibin alpha-subunit, Melan A (show MLANA Proteins) and MNF116 were not sensitive for pheochromocytomas.
Inhibin alpha gene expression in human trophoblasts is regulated by interactions between TFAP2 (show TFAP2A Proteins) and cAMP signaling pathways.
For INHA gene c.-124G>A, males carrying c.-124GG genotype and c.-124GA genotype showed an increased risk of non-normozoospermic syndrome.
Maternal serum inhibin-A levels were significantly higher in pregnancies with fetal Hb Bart's disease.
Serum inhibin levels correlate with clinical characteristics and mortality in epithelial ovarian cancer patients.
When two variant alleles of inhibin alpha gene promoter are combined, the c.-16C>T and c.-124A>G polymorphisms are associated with increased primary ovarian insufficiency risk in Korean women.
This study provides evidence that the expressions of inhibin alpha subunit and betaglycan (show TGFBR3 Proteins) are inferior in cystic follicles, and this may be caused by the decrease in FSH (show BRD2 Proteins) in the presence of a cystic follicle.
The c.-42G>A and c.3222G>A polymorphisms in the INHA gene are significantly associated with follicular cysts in sows.
INHA and INHB expression and cellular localization in porcine oocytes were studied.
Association of the INHA gene to ovulation rate.
inhibin alpha-subunits were localized in the granulosa cells of follicles at all stages but were not localized in corpora lutea.
The expression of the components of the activin-inhibin-follistatin (show FST Proteins) system is altered in bovine cystic ovarian disease.
INHA gene can be used as a predictor for superovulation in Chinese Holstein cows.
Inhibin has a negative autocrine or paracrine effect on the in vitro capacity of granulosa cells isolated from dominant or subordinate follicles to produce estradiol.
overexpression of inhibin alpha (1-32) fragment regulated granulosa cell development and effects on subsequent oocyte maturation were both time- and stage-dependent
The result showed that AA genotype had remarkable litter size at P1 locus in the three goat breeds (P < 0.05). Therefore, these results suggest that INHA gene is a strong candidate gene that affects litter size in goats.
Sequence comparison showed that three base changes in INHA(two amino acid substitutions), and three base changes in INHBA (show INHBA Proteins),(one amino acid substitution). No difference seen in INHA or INHBA (show INHBA Proteins) mRNA expression level in the follicle of the two goat breeds.
This gene encodes the alpha subunit of inhibins A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion.
inhibin alpha chain
, inhibin alpha subunit
, inhibin alpha subunit variant 1
, inhibin, alpha
, A-inhibin subunit
, inhibin alpha-subunit
, inhibin A
, inhibin precursor alpha subunit
, Inhibin alpha chain