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The protein encoded by IBTK binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. Additionally we are shipping and many more products for this protein.
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Human Polyclonal IBTK Primary Antibody for FACS, IHC (p) - ABIN654688
Spatuzza, Schiavone, Di Salle, Janda, Sardiello, Fiume, Fierro, Simonetta, Argiriou, Faraonio, Capparelli, Quinto, Scala: Physical and functional characterization of the genetic locus of IBtk, an inhibitor of Bruton's tyrosine kinase: evidence for three protein isoforms of IBtk. in Nucleic acids research 2008
Show all 2 references for ABIN654688
Human Polyclonal IBTK Primary Antibody for EIA, FACS - ABIN952814
Fiume, Rossi, Di Salle, Spatuzza, Mallardo, Scala, Quinto: Computational analysis and in vivo validation of a microRNA encoded by the IBTK gene, a regulator of B-lymphocytes differentiation and survival. in Computational biology and chemistry 2009
Show all 2 references for ABIN952814
CRL3 (show IL31RA Antibodies)(IBTK) is a novel ubiquitin ligase with regulatory roles in cellular pathways, such as the Pdcd4 (show PDCD4 Antibodies)-dependent translation of mRNAs
Depletion of IBTKalpha by short hairpin RNA reduced viability of cultured cells coincident with increased caspase 3 (show CASP3 Antibodies)/7 cleavage, suggesting that IBTKalpha is a key regulator in determining cell fate during the UPR.
A novel pathway of Btk (show BTK Antibodies) regulation via protein kinase C (show PKC Antibodies) phosphorylation of IBtkgamma.
three novel (Ala347fsX55, I355T, and Thr324fsX24) mutations in Bruton's tyrosine kinase (show BTK Antibodies) in patients with X-linked agammaglobulinemia
The IBTK gene encodes the proteins IBtk-alpha, beta and gamma that regulate the B cell receptor signalling through Bruton's tyrosine kinase (show BTK Antibodies), which promotes B cell survival and differentiation.
The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription.
inhibitor of Bruton agammaglobulinemia tyrosine kinase
, inhibitor of Bruton's tyrosine kinase
, inhibitor of Bruton tyrosine kinase-like
, BTK-binding protein
, Bruton agammaglobulinemia tyrosine kinase inhibitor
, inhibitor of Bruton tyrosine kinase
, inhibitor of Bruton's tyrosine kinase-alpha
, inhibitor of Bruton's tyrosine kinase-beta
, inhibitor of Bruton's tyrosine kinase-gamma