Inhibitor of DNA Binding 1, Dominant Negative Helix-Loop-Helix Protein Proteins (ID1)

The protein encoded by ID1 is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. Additionally we are shipping ID1 Antibodies (79) and ID1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ID1 15901  
ID1 25261 P41135
ID1 3397 P41134
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Top ID1 Proteins at antibodies-online.com

Showing 7 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,374.17
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag   50 μg Log in to see 11 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$498.21
Details

ID1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , , ,
, , ,

Top referenced ID1 Proteins

  1. Human ID1 Protein expressed in Wheat germ - ABIN1307349 : Edhayan, Ohara, Stinson, Amin, Isozaki, Ha, Haines, Morgan, Campbell, Arbab, Friday, Fox, Ruth: Inflammatory properties of inhibitor of DNA binding 1 secreted by synovial fibroblasts in rheumatoid arthritis. in Arthritis research & therapy 2016 (PubMed)

More Proteins for Inhibitor of DNA Binding 1, Dominant Negative Helix-Loop-Helix Protein (ID1) Interaction Partners

Zebrafish Inhibitor of DNA Binding 1, Dominant Negative Helix-Loop-Helix Protein (ID1) interaction partners

  1. Gain and loss of id1 function in vivo demonstrated that Id1 promotes stem cell quiescence. The increased id1 expression observed in neural stem cells in response to injury appeared independent of inflammatory signals.

Mouse (Murine) Inhibitor of DNA Binding 1, Dominant Negative Helix-Loop-Helix Protein (ID1) interaction partners

  1. Id1 enables both Lewis lung carcinoma cells and the host microenvironment for an effective liver colonization.

  2. adipose tissue-specific overexpression of Id1 causes age-associated and high-fat diet-induced obesity in mice. Id1 suppresses BAT (show BAAT Proteins) thermogenesis by binding to and suppressing PGC1alpha transcriptional activity. Lack of Id1 increases beige gene and Ucp1 (show UCP1 Proteins) expression in the WAT in response to cold exposure. Furthermore, brown-like differentiation is increased in Id1-deficient mouse embryonic fibroblasts.

  3. If Gfi1 (show ZNF163 Proteins) levels fall below a threshold, Id1 expression increases and renders E2A (show TCF3 Proteins) unable to function, which prevents hematopoietic progenitors from engaging along the B lymphoid lineage

  4. Id1 may promote cell cycle progression of endothelial progenitor cells (EPCs), and that Wnt2 (show WNT2 Proteins) may be important in Id1 regulation of the cell cycle of EPCs.

  5. Differential role of Id1 in MLL (show MLL Proteins)-AF9 (show MLLT3 Proteins)-driven leukemia based on cell of origin

  6. Collectively, our results suggest that ENH1 plays an important role in the activation of myogenesis through the repression of Id2 activity.

  7. Data indicate that upregulation of E2-2 (show TCF4 Proteins) protein markedly attenuated the inhibitor of DNA-binding 1 (ID1)-mediated increase in endothelial progenitor cells (EPCs) proliferation and migration.

  8. our results strongly suggest that Usp1 (show USP1 Proteins) is involved in the regulation of centrosome duplication, at least in part via ID1, and Usp1 (show USP1 Proteins) may exert its oncogenic activity, partially through inducing centrosome abnormality.

  9. demonstrated that Id1 and E2-2 (show TCF4 Proteins) are critical regulators of EPCs function in vitro. Id1 interacts with E2-2 (show TCF4 Proteins) and relieves the E2-2 (show TCF4 Proteins)-mediated repression of FGFR1 (show FGFR1 Proteins) and VEGFR2 (show KDR Proteins) expression to modulate EPCs functions

  10. Endothelial ID1 up-regulation in inflamed colonic mucosa is an adaptive response that modulates the severity of tissue injury.

Human Inhibitor of DNA Binding 1, Dominant Negative Helix-Loop-Helix Protein (ID1) interaction partners

  1. Id1 enables lung cancer liver colonization by activating an epithelial mesenchymal transformation program in tumor cells and establishing the pre-metastatic niche.

  2. High ID1 expression is associated with breast cancer.

  3. ID1 expression impacts the sensitivity of colon cancer cells to 5-FU and may be considered as a potential predictive marker in colorectal carcinoma treatment.

  4. Reducing ID1 gene expression reduces metastatic spread of salivary gland neoplasms.

  5. High ID-1 expression is associated with colorectal carcinoma.

  6. ID1 expression was positively related to drug resistance of EGFR (show EGFR Proteins)-TKI in non-small cell lung cancer.

  7. MVD was determined by immunohistochemistry, and the expressions of mRNA and protein of inhibitor of differentiation-1 (ID1) and vascular endothelial growth factor (VEGF) were detected in gastric cancer.

  8. ID1 down-regulation induced parallel changes in the IGF and AKT (show AKT1 Proteins) pathways. The crosstalk of these pathways may enhance malignant phenotypes in salivary gland cancer.

  9. Results show that ID1, ID3 (show ID3 Proteins) and IGJ (show IGJ Proteins) genes are highly expressed in adult B-ALL and correlate with poor prognosis in Hispanic patients.

  10. Our findings define an intricate E2F1-dependent mechanism by which Id1 increases thymidylate synthase and IGF2 expressions to promote cancer chemoresistance. The Id1-E2F1-IGF2 regulatory axis has important implications for cancer prognosis and treatment.

ID1 Protein Profile

Protein Summary

The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ID1

  • inhibitor of DNA binding 1 (id1)
  • inhibitor of DNA binding 1, dominant negative helix-loop-helix protein (ID1)
  • inhibitor of DNA binding 1 (Id1)
  • AI323524 protein
  • bHLHb24 protein
  • cb108 protein
  • D2Wsu140e protein
  • ID protein
  • ID1 protein
  • id6 protein
  • ID125A protein
  • Idb1 protein
  • wu:fb57e11 protein

Protein level used designations for ID1

inhibitor of DNA binding 1 , DNA-binding protein inhibitor id-1 , inhibitor of DNA binding 1, dominant negative helix-loop-helix protein , DNA-binding protein inhibitor ID-1 , inhibitor of DNA binding 6 , Inhibitor of DNA binding 1 helix-loop-helix protein (splice varaiation) , Inhibitor of DNA binding 1, helix-loop-helix protein (splice variation) , class B basic helix-loop-helix protein 24 , dJ857M17.1.2 (inhibitor of DNA binding 1, dominant negative helix-loop-helix protein) , inhibitor of differentiation 1 , helix-loop-helix protein

GENE ID SPECIES
100528658 Ictalurus punctatus
469912 Pan troglodytes
30493 Danio rerio
15901 Mus musculus
25261 Rattus norvegicus
3397 Homo sapiens
609779 Canis lupus familiaris
100522839 Sus scrofa
497011 Bos taurus
395282 Gallus gallus
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