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Inhibitor of Growth Family, Member 1 Proteins (ING1)

ING1 encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. Additionally we are shipping Inhibitor of Growth Family, Member 1 Antibodies (132) and Inhibitor of Growth Family, Member 1 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ING1 3621 Q9UK53
ING1 26356 Q9QXV3
Rat ING1 ING1 306626  
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Top Inhibitor of Growth Family, Member 1 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$413.21
Details
HOST_Baculovirus infected Insect Cells Human His tag   50 μg Log in to see 10 to 12 Days
$570.24
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HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ING1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine)

More Proteins for Inhibitor of Growth Family, Member 1 (ING1) Interaction Partners

Human Inhibitor of Growth Family, Member 1 (ING1) interaction partners

  1. ING1a acts as a novel link in the activation of the Rb pathway that can impose senescence in the absence of activating p53 (show TP53 Proteins)-mediated DNA damage signaling, and should prove useful in defining the molecular events contributing to Rb-induced senescence.

  2. These data indicate that stromal ING1 expression can predict the survival of patients with luminal breast cancer

  3. Overexpression of let-7b in gastric cancer can inhibit invasion and migration of gastric cancer cells through directly targeting the tumor metastasis-associated gene ING1.

  4. Results show that ING1 expression is under-regulated in pancreatic duct adenocarcinoma (PDAC) and is a direct target of miR (show MLXIP Proteins)-371-5p involved in miR (show MLXIP Proteins)-371-5p inducing promotion of PDAC cells proliferation.

  5. ING1b finely regulates the hypoxic response by triggering HIF1alpha (show HIF1A Proteins) proteasomal degradation.

  6. ING1b sumoylation regulates the binding of ING1b to the ISG15 (show ISG15 Proteins) and DGCR8 (show DGCR8 Proteins) promoters, consequently regulating ISG15 (show ISG15 Proteins) and DGCR8 (show DGCR8 Proteins) transcription.

  7. Our results identify a novel functional relationship between cytoplasmic p33ING1b and oral squamous cell carcinoma patient survival

  8. ING1 translocates to the mitochondria of primary fibroblasts and established epithelial cell lines in response to apoptosis inducing stimuli, independent of the cellular p53 (show TP53 Proteins) status.

  9. ING1 acts at early stages of the DNA damage response activating a variety of repair mechanisms.

  10. Src (show SRC Proteins) may play a major role in regulating ING1 levels during tumorigenesis in those cancers in which high levels of Src (show SRC Proteins) expression or activity are present.

Mouse (Murine) Inhibitor of Growth Family, Member 1 (ING1) interaction partners

  1. ING1b is an important regulator of osteoblast differentiation and suppresses PPAR-beta (show PPARD Proteins)/delta.

  2. Increased melanoma formation and dissemination in TyrNRas mice deficient in the tumor suppressor Ing1.

  3. Study reveals a novel connection between ING1 and a regulator of microRNA biogenesis and identifies new links between tumor suppressor proteins and the microRNA machinery.

  4. Identification of the p33(ING1)-regulated genes that include cyclin B1 (show CCNB1 Proteins) and proto-oncogene (show RAB1A Proteins) DEK (show DEK Proteins) by using cDNA microarray in a mouse mammary epithelial cell line NMuMG

  5. Characterization of nuclear localization signal in mouse ING1 homolog protein.

  6. p33ING1 expression induces features of cellular senescence through two silencing domains and interaction with Ras

  7. the suggested role of ing1 as a candidate tumor suppressor gene involved in control of DNA damage response.

  8. p37 (show UBXN2B Proteins)(Ing1) can negatively regulate cell growth and apoptosis in a p53 (show TP53 Proteins)-independent manner.

  9. important role for the Ing1 locus in protection against oncogenic stress in vivo, both as a mediator of p53 (show TP53 Proteins) activation and as a regulator of chromatin remodeling processes.

  10. Analysis of marker gene expression in p37 (show UBXN2B Proteins)(Ing1b)/p53 (show TP53 Proteins) null tumors indicates that the double-null mice develop both nongerminal center and germinal center B-cell-like DLBL.

Inhibitor of Growth Family, Member 1 (ING1) Protein Profile

Protein Summary

This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene names and symbols associated with ING1

  • inhibitor of growth family, member 1 (ING1)
  • inhibitor of growth family, member 1 (ing1)
  • inhibitor of growth family, member 1 (Ing1)
  • inhibitor of growth family, member 5b (ing5b)
  • 2610028J21Rik protein
  • AA407184 protein
  • AI875420 protein
  • ING1 protein
  • mING1h protein
  • p24ING1c protein
  • p33 protein
  • p33Ing1 protein
  • p33ING1b protein
  • p33ING1c protein
  • p37Ing1b protein
  • p47 protein
  • p47ING1a protein
  • si:busm1-40g1.1 protein
  • si:dz40g1.1 protein
  • wu:fc94a02 protein
  • xing1 protein
  • zgc:100910 protein
  • zgc:136918 protein

Protein level used designations for ING1

inhibitor of growth family, member 1 , inhibitor of growth protein 1 , growth inhibitor ING1 , growth inhibitory protein ING1 , tumor suppressor ING1 , inhibitor of growth , tumor suppressor

GENE ID SPECIES
418759 Gallus gallus
678608 Danio rerio
694955 Macaca mulatta
736462 Pan troglodytes
3621 Homo sapiens
26356 Mus musculus
306626 Rattus norvegicus
779040 Xenopus laevis
476984 Canis lupus familiaris
513047 Bos taurus
368450 Danio rerio
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