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The protein encoded by ING5 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. Additionally we are shipping ING5 Antibodies (51) and ING5 Proteins (6) and many more products for this protein.
miR (show MLXIP ELISA Kits)-331-3p is upregulated by HBV and promotes proliferation of hepatocellular carcinoma cells though repression of ING5 expression.
Suggest that ING5 expression might be a good marker for gastric carcinogenesis and its subsequent progression by inhibiting proliferation, growth, migration, invasion and metastasis.
Loss of ING5 expression is associated with lung cancer.
Identified ING5 as a novel CDK2 (show CDK2 ELISA Kits) substrate. ING5 is phosphorylated at a single site, threonine 152, by cyclin E (show CCNE1 ELISA Kits)/CDK2 (show CDK2 ELISA Kits) and cyclin A (show CCNA2 ELISA Kits)/CDK2 (show CDK2 ELISA Kits). This site is also phosphorylated in cells in a cell cycle dependent manner, consistent with it being a CDK2 (show CDK2 ELISA Kits) substrate.
Results showed that ING5 gene expression is inhibited by miR (show MLXIP ELISA Kits)-193a-3p and is instrumental in miR (show MLXIP ELISA Kits)-193a-3p's role in activating BCa (show BLNK ELISA Kits) chemoresistance.
Data indicate that ING5 associates with Tip60 (KAT5 (show KAT5 ELISA Kits)) to form a complex with p53 (show TP53 ELISA Kits).
ING5 down-regulation promotes bone mesenchymal stem cell proliferation.
Results indicate that ING5 is a growth suppressor with suppressed expression in AML whose functions depend on its interaction with INCA1.
EBNA3C negatively regulate p53 (show TP53 ELISA Kits)-mediated functions by interacting with ING4 (show ING4 ELISA Kits) and ING5.
Aberrant inhibitor of growth (show ING1 ELISA Kits) 5 expression may contribute to pathogenesis, growth, and invasion of colorectal carcinomas.
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway.
inhibitor of growth family, member 5
, inhibitor of growth protein 5