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Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Additionally we are shipping IMPDH1 Proteins (8) and many more products for this protein.
Showing 10 out of 80 products:
Human Monoclonal IMPDH1 Primary Antibody for ELISA, WB - ABIN561487
Batovska, Kim, Mitsuhashi, Cho, Kwon, Ubukata: Hydroxamic acid derivatives of mycophenolic acid inhibit histone deacetylase at the cellular level. in Bioscience, biotechnology, and biochemistry 2008
Show all 2 references for ABIN561487
Chicken Polyclonal IMPDH1 Primary Antibody for IHC, WB - ABIN2785671
Wang, Yang, Zeevi, Webber, Girnita, Selby, Fu, Shah, Pravica, Hutchinson, Burckart: IMPDH1 gene polymorphisms and association with acute rejection in renal transplant patients. in Clinical pharmacology and therapeutics 2008
Human Polyclonal IMPDH1 Primary Antibody for IHC (p), WB - ABIN658602
Kagaya, Miura, Saito, Habuchi, Satoh: Correlation of IMPDH1 gene polymorphisms with subclinical acute rejection and mycophenolic acid exposure parameters on day 28 after renal transplantation. in Basic & clinical pharmacology & toxicology 2010
IMP (show BRAP Antibodies) dehydrogenase type 1 associates with polyribosomes translating rhodopsin (show RHO Antibodies) mRNA
We conclude that both IMPDH and HPRT (show HPRT1 Antibodies) activities contribute to normal T-lymphocyte activation and function
Retinitis pigmentosa-causing mutations identified in IMPDH1 gene. High level of IMPDH1 in photoreceptors, low levels in other layers of retina.
IMPDH1 mutations cause photoreceptor degeneration in retinitis pigmentosa
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors (By similarity).
IMP (inosine monophosphate) dehydrogenase 1
, inosine 5'-phosphate dehydrogenase 1
, inosine monophosphate dehydrogenase 1
, IMP dehydrogenase 1
, inosine-5'-monophosphate dehydrogenase 1
, IMPD 1
, IMPDH 1
, IMP dehydrogenase 1b
, inosine-5'-monophosphate dehydrogenase 1b