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anti-Inosine Triphosphatase (ITPA) Antibodies

The protein encoded by ITPA hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. Additionally we are shipping Inosine Triphosphatase Proteins (25) and Inosine Triphosphatase Kits (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ITPA 3704 Q9BY32
ITPA 311422 D3ZW55
ITPA 16434 Q9D892
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Top anti-Inosine Triphosphatase Antibodies at antibodies-online.com

Showing 10 out of 77 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of ITPA Antibody (N-term) (ABIN651135) in A375 cell line lysates (35 µg/lane). ITPA (arrow) was detected using the purified polyclonal antibody. ITPA Antibody (N-term) (ABIN651135) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using ITPA antibody. 200 μL Log in to see 9 Days
$588.50
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged ITPA is 3 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 14 Days
$175.80
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image ITPase antibody [N1C3] detects ITPase protein at cytosol on Ca922 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded Ca922 xenograft. ITPase antibody [N1C3] , dilution: 1:500. WB Image Sample(30 ug whole cell lysate) A:293T B:Hep G2 , 12% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB ITPA Antibody (C-term)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the ITPA antibody detected the ITPA protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: ITPA Antibody [NBP1-32494] - Sample(30 ug whole cell lysate)A:293TB:Hep G2 (GTX27900)12% SDS PAGE, antibody diluted at 1:1000. 100 μL Log in to see 7 to 9 Days
$447.56
Details
Human Rabbit Un-conjugated FACS, ICC, IF, IHC (p), WB Immunocytochemistry/Immunofluorescence: ITPA Antibody [NBP2-30059] - Immunofluorescent analysis of Hela cells, using (N-term)(NBP2-30059). NBP2-30059 was diluted at 1:25 dilution. Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Dylight Fluor 554 (red) conjugated Phalloidin (red). Flow Cytometry: ITPA Antibody [NBP2-30059] - Flow cytometric analysis of A375 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 0.4 mL Log in to see 8 to 11 Days
$408.19
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: ITPA Antibody [NBP1-88296] - Staining of human cell line U-2 OS shows positivity in cytoplasm. Immunohistochemistry-Paraffin: ITPA Antibody [NBP1-88296] - Staining of human thyroid gland shows moderate cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Mouse Un-conjugated ELISA   100 μg Log in to see 7 to 9 Days
$537.17
Details

ITPA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Inosine Triphosphatase Antibodies

  1. Mouse (Murine) Polyclonal ITPA Primary Antibody for IHC, WB - ABIN3021765 : Lin, McLennan, Ying, Wang, Gu, Jin, Wu, Liu, Yuan, Tang, Xie, Mao: Cloning, expression, and characterization of a human inosine triphosphate pyrophosphatase encoded by the itpa gene. in The Journal of biological chemistry 2001 (PubMed)
    Show all 2 references for ABIN3021765

  2. Human Polyclonal ITPA Primary Antibody for FACS, IF - ABIN651135 : Fellay, Thompson, Ge, Gumbs, Urban, Shianna, Little, Qiu, Bertelsen, Watson, Warner, Muir, Brass, Albrecht, Sulkowski, McHutchison, Goldstein: ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. in Nature 2010 (PubMed)
    Show all 2 references for ABIN651135

  3. Human Monoclonal ITPA Primary Antibody for ELISA - ABIN517268 : Vroemen, Munnix, Bakker, Bierau, Huts, Leers: A novel multiparameter flow cytometric assay for inosine triphosphatase expression analysis in leukocytes. in Cytometry. Part A : the journal of the International Society for Analytical Cytology 2012 (PubMed)

More Antibodies against Inosine Triphosphatase Interaction Partners

Human Inosine Triphosphatase (ITPA) interaction partners

  1. A high prevalence of the ITPA polymorphisms associated with ribavirin-induced hemolytic anemia was found in Mexican Native Amerindians.

  2. ITPA gene is associated with protection of anemia in patients with chronic hepatitis during antiviral therapy.

  3. We concluded that ITPase activity plays an important function and that ATP concentration changes due to therapy are related to the Hb decreasing mechanism in the early period of therapy with HCV treatment

  4. The aim of the study was to investigate frequencies of TPMT (show TPMT Antibodies) and ITPA polymorphisms in Lithuanian inflammatory bowel disease patients and analyze their association with azathioprine-related adverse events.

  5. ITPA polymorphism was associated with RBV-induced anemia and thrombocytopenia in Egyptian patients with hepatitis C virus genotype 4 infection.

  6. Hyperbilirubinemia develops at early time points after simeprevir administration in most cases and is dependent on the ITPA genotype.

  7. Genetic variants in inosine triphosphatase (ITPA) gene have been linked to the haemolytic anaemia induced by peg (show PAEP Antibodies)-interferon (show IFNA Antibodies) and ribavirin treatment.

  8. The association of IL28B (show IL28B Antibodies) and APOH (show APOH Antibodies) single nucleotide polymorphisms (SNPs) with sustained virological response and of ITPA SNPs with anemia related phenotypes.

  9. The identification of ITPA protective and SLC29A1 (show SLC29A1 Antibodies) risk genotypes still appears to be a current methodology in Ribavirin dosing during hepatitis C virus therapy with direct acting antiviral agents

  10. ITPA SNPs in Brazilian patients receiving antiviral therapy for chronic hepatitis had a great propensity for developing ribavirin-induced anaemia.

Mouse (Murine) Inosine Triphosphatase (ITPA) interaction partners

  1. In the mouse genome, we found one processed Itpa gene-like sequence and two processed Itpa pseudogenes as well as the Itpa gene itself with introns.

  2. The role of ITPase in mice is to exclude ITP from the ATP pool, and the main target substrate of this enzyme is rITP

Inosine Triphosphatase (ITPA) Antigen Profile

Protein Summary

This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with ITPA

  • inosine triphosphatase (itpa) antibody
  • inosine triphosphatase (LOC100345066) antibody
  • inosine triphosphatase (LOC733043) antibody
  • inosine triphosphatase (LOC100157088) antibody
  • inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA) antibody
  • inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (Itpa) antibody
  • inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (itpa) antibody
  • LOC100283993 (pco148511) antibody
  • nucleoside-triphosphatase, cancer-related (NTPCR) antibody
  • 2010016I08Rik antibody
  • AU020102 antibody
  • C1orf57 antibody
  • C20orf37 antibody
  • DDBDRAFT_0215619 antibody
  • DDBDRAFT_0238062 antibody
  • DDB_0215619 antibody
  • DDB_0238062 antibody
  • dJ794I6.3 antibody
  • HCR-NTPase antibody
  • HLC14-06-P antibody
  • Itp antibody
  • ITPase antibody
  • NTPase antibody
  • RP4-678E16.2 antibody
  • si:ch73-18j6.1 antibody
  • si:dkey-19f21.1 antibody

Protein level used designations for ITPA

inosine triphosphate pyrophosphatase , inosine triphosphatase , ITPase , NTPase , inosine triphosphatase-A , inosine triphosphate pyrophosphohydrolase , non-canonical purine NTP pyrophosphatase , non-standard purine NTP pyrophosphatase , nucleoside-triphosphate diphosphatase , putative oncogene protein HLC14-06-P , nucleoside-triphosphate pyrophosphatase , nucleoside triphosphate pyrophosphatase , inosine triphosphatase A , Non-canonical purine NTP pyrophosphatase , Non-standard purine NTP pyrophosphatase , Nucleoside-triphosphate diphosphatase , Nucleoside-triphosphate pyrophosphatase , Inosine triphosphatase , PCO148511_ov , hypothetical protein , pco148511(169) , cancer-related nucleoside-triphosphatase , human cancer-related NTPase , nucleoside triphosphate phosphohydrolase , nucleoside-triphosphatase C1orf57

GENE ID SPECIES
8625642 Dictyostelium discoideum AX4
100345066 Oryctolagus cuniculus
733043 Bombyx mori
100157088 Sus scrofa
3704 Homo sapiens
311422 Rattus norvegicus
16434 Mus musculus
613653 Bos taurus
424390 Gallus gallus
735008 Xenopus laevis
557834 Danio rerio
100283993 Zea mays
84284 Homo sapiens
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