Inosine Triphosphatase Proteins (ITPA)

ITPA encodes an inosine triphosphate pyrophosphohydrolase. Additionally we are shipping Inosine Triphosphatase Antibodies (80) and Inosine Triphosphatase Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ITPA 3704 Q9BY32
ITPA 311422 D3ZW55
ITPA 16434 Q9D892
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Top Inosine Triphosphatase Proteins at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
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Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
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HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$319.00
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HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$333.33
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HOST_Escherichia coli (E. coli) Human His tag Validation with Western Blot 10 μg Log in to see 12 to 15 Days
$345.35
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HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 4 Days
$522.50
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
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HOST_Escherichia coli (E. coli) Human His tag   10 μg Log in to see 15 to 16 Days
$300.00
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Yeast REACT_Sea Squirt His tag   1 mg Log in to see 60 to 71 Days
$2,460.33
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Yeast Xenopus laevis His tag   1 mg Log in to see 60 to 71 Days
$2,469.50
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ITPA Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Rat (Rattus)

Mouse (Murine) ,
,

Top referenced Inosine Triphosphatase Proteins

  1. Human ITPA Protein expressed in Escherichia coli (E. coli) - ABIN667158 : Clawson, Song, Schwartz, Shukla, Patel, Connor, Blankenship, Hatem, Kumar: Interaction of human immunodeficiency virus type I Rev protein with nuclear scaffold nucleoside triphosphatase activity. in Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1992 (PubMed)
    Show all 2 references for 667158

  2. Human ITPA Protein expressed in Wheat germ - ABIN1308243 : Bierau, Bakker, Schippers, Grashorn, Lindhout, Lowe, Paulussen, Verbon: Erythrocyte inosine triphosphatase activity is decreased in HIV-seropositive individuals. in PLoS ONE 2012 (PubMed)

More Proteins for Inosine Triphosphatase (ITPA) Interaction Partners

Human Inosine Triphosphatase (ITPA) interaction partners

  1. Inosine triphosphatase (IPTA) rs1127354 variants but not rs7270101 were found in Chinese patients infected with chronic hepatitis C. IPTA rs1127354 variants and related ITPase were not only related with ribavirin-induced hemolytic anemia but also directly affected the virological response to pegylated interferon (show IFNA Proteins) plus ribavirin combination therapy in Chinese chronic hepatitis C virus-infected patients.

  2. This study concluded that HIV-infection seems to be interfering with the nucleotide metabolism in leukocytes, including CD4 (show CD4 Proteins) lymphocytes, by decreasing ITPase expression, independently of ITPA genotype.

  3. A high prevalence of the ITPA polymorphisms associated with ribavirin-induced hemolytic anemia was found in Mexican Native Amerindians.

  4. ITPA gene is associated with protection of anemia in patients with chronic hepatitis during antiviral therapy.

  5. We concluded that ITPase activity plays an important function and that ATP concentration changes due to therapy are related to the Hb decreasing mechanism in the early period of therapy with HCV treatment

  6. The aim of the study was to investigate frequencies of TPMT (show TPMT Proteins) and ITPA polymorphisms in Lithuanian inflammatory bowel disease patients and analyze their association with azathioprine-related adverse events.

  7. ITPA polymorphism was associated with RBV-induced anemia and thrombocytopenia in Egyptian patients with hepatitis C virus genotype 4 infection.

  8. Hyperbilirubinemia develops at early time points after simeprevir administration in most cases and is dependent on the ITPA genotype.

  9. Genetic variants in inosine triphosphatase (ITPA) gene have been linked to the haemolytic anaemia induced by peg (show PAEP Proteins)-interferon (show IFNA Proteins) and ribavirin treatment.

  10. The association of IL28B (show IL28B Proteins) and APOH (show APOH Proteins) single nucleotide polymorphisms (SNPs) with sustained virological response and of ITPA SNPs with anemia related phenotypes.

Mouse (Murine) Inosine Triphosphatase (ITPA) interaction partners

  1. In the mouse genome, we found one processed Itpa gene-like sequence and two processed Itpa pseudogenes as well as the Itpa gene itself with introns.

  2. The role of ITPase in mice is to exclude ITP from the ATP pool, and the main target substrate of this enzyme is rITP

Inosine Triphosphatase (ITPA) Protein Profile

Protein Summary

This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with Inosine Triphosphatase Proteins (ITPA)

  • inosine triphosphatase (itpa)
  • inosine triphosphatase (LOC100345066)
  • inosine triphosphatase (LOC733043)
  • inosine triphosphatase (LOC100157088)
  • inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA)
  • inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (Itpa)
  • inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (itpa)
  • LOC100283993 (pco148511)
  • nucleoside-triphosphatase, cancer-related (NTPCR)
  • 2010016I08Rik protein
  • AU020102 protein
  • C1orf57 protein
  • C20orf37 protein
  • DDBDRAFT_0215619 protein
  • DDBDRAFT_0238062 protein
  • DDB_0215619 protein
  • DDB_0238062 protein
  • dJ794I6.3 protein
  • HCR-NTPase protein
  • HLC14-06-P protein
  • Itp protein
  • ITPase protein
  • NTPase protein
  • RP4-678E16.2 protein
  • si:ch73-18j6.1 protein
  • si:dkey-19f21.1 protein

Protein level used designations for Inosine Triphosphatase Proteins (ITPA)

inosine triphosphate pyrophosphatase , inosine triphosphatase , ITPase , NTPase , inosine triphosphatase-A , inosine triphosphate pyrophosphohydrolase , non-canonical purine NTP pyrophosphatase , non-standard purine NTP pyrophosphatase , nucleoside-triphosphate diphosphatase , putative oncogene protein HLC14-06-P , nucleoside-triphosphate pyrophosphatase , nucleoside triphosphate pyrophosphatase , inosine triphosphatase A , Non-canonical purine NTP pyrophosphatase , Non-standard purine NTP pyrophosphatase , Nucleoside-triphosphate diphosphatase , Nucleoside-triphosphate pyrophosphatase , Inosine triphosphatase , PCO148511_ov , hypothetical protein , pco148511(169) , cancer-related nucleoside-triphosphatase , human cancer-related NTPase , nucleoside triphosphate phosphohydrolase , nucleoside-triphosphatase C1orf57

GENE ID SPECIES
8625642 Dictyostelium discoideum AX4
100345066 Oryctolagus cuniculus
733043 Bombyx mori
100157088 Sus scrofa
3704 Homo sapiens
311422 Rattus norvegicus
16434 Mus musculus
613653 Bos taurus
424390 Gallus gallus
735008 Xenopus laevis
557834 Danio rerio
100283993 Zea mays
84284 Homo sapiens
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