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IP6K1 encodes a member of the inositol phosphokinase family. Additionally we are shipping IP6K1 Proteins (6) and many more products for this protein.
Showing 10 out of 45 products:
Human Polyclonal IP6K1 Primary Antibody for EIA, WB - ABIN952910
Morgan, Han, Lam, Fraser, Ferguson: Association analysis of 3p21 with Crohn's disease in a New Zealand population. in Human immunology 2010
Show all 5 references for ABIN952910
Human Polyclonal IP6K1 Primary Antibody for ICC, IF - ABIN4327446
Jadav, Chanduri, Sengupta, Bhandari: Inositol pyrophosphate synthesis by inositol hexakisphosphate kinase 1 is required for homologous recombination repair. in The Journal of biological chemistry 2013
IP6K1 is also involved in early cytoskeleton remodeling events during cancer progression.
IP6K1 is a novel CRL4 subunit that transduces UV signals to mediate disassembly of the CRL4-CSN complex, thereby regulating nucleotide excision repair and cell death.
we identified IP6Ks as novel nuclear and cytosolic InsP6- (and InsP5-) dephosphorylating enzymes whose activity is sensitively driven by a decrease in the cellular ATP/ADP ratio
FGF2 (show FGF2 Antibodies)-signaling involves the inositol polyphosphate cascade, including inositol hexakisphosphate kinase (IP6K), and demonstrate that IP6K1,2 regulates Runx2 (show RUNX2 Antibodies) and osteoblast gene expression.
IHPK1 gene is disrupted at the 3p21.31 breakpoint of t(3;9) in a family with type 2 diabetes mellitus
Results report the characterization of an inhibitor, N(2)-(m-(trifluoromethy)lbenzyl) N(6)-(p-nitrobenzyl)purine (TNP), selective for inositol hexakisphosphate kinases.
IP6K1 preferentially bound to the phospholipid phosphatidic acid, and this binding was required for IP6K1 nuclear localization and the regulation of inositol-3-phosphate synthase transcription.
present study demonstrates that IP6K1 physiologically regulates GSK3 (show GSK3b Antibodies) kinases.
IP6K1 has a role in regulation of mammalian hemostasis via its control of platelet polyP levels
Mouse embryonic fibroblasts (MEFs) lacking IP6K1 exhibit impaired DNA damage repair via homologous recombination.
Defects in the mutants indicate important roles for IP6K1 and inositol pyrophosphates in several physiological functions
This gene encodes a member of the inositol phosphokinase family. The encoded protein may be responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternatively spliced transcript variants have been described.
inositol hexaphosphate kinase 1
, inositol hexakisphosphate kinase 1
, inositol hexakisphosphate kinase 6
, insP6 kinase 1
, ATP:1D-myo-inositol-hexakisphosphate phosphotransferase
, Pi uptake stimulator