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Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) ELISA Kits

INPP5D is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Additionally we are shipping Inositol Polyphosphate-5-Phosphatase, 145kDa Antibodies (106) and Inositol Polyphosphate-5-Phosphatase, 145kDa Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
INPP5D 16331 Q9ES52
INPP5D 54259 P97573
INPP5D 3635 Q92835
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Top Inositol Polyphosphate-5-Phosphatase, 145kDa ELISA Kits at antibodies-online.com

Showing 4 out of 9 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.312-20 ng/mL 96 Tests Log in to see 11 to 13 Days
$946.00
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Human
  96 Tests Log in to see 2 to 3 Days
$480.00
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Mouse
0.78-50 ng/mL   96 Tests Log in to see 11 to 13 Days
$946.00
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Rat
1.56-100 ng/mL   96 Tests Log in to see 11 to 13 Days
$946.00
Details

More ELISA Kits for Inositol Polyphosphate-5-Phosphatase, 145kDa Interaction Partners

Zebrafish Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) interaction partners

Mouse (Murine) Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) interaction partners

  1. Our results describe a critical role for SHIP-1 in regulating the ability of dendritic cells to efficiently prime Th2-type responses.

  2. Findings indicate a role for inositol-polyphosphate 5-phosphatase SHIP-1 coupling to DC-type lectin receptor ectin-1 hemITAM in the selective control of downstream responses.

  3. miR (show MLXIP ELISA Kits)-155 regulates the delicate balance between PAK1 (show PAK1 ELISA Kits)-mediated proliferation and apoptosis in T cells impacting lymphoid organ size and function.

  4. miR (show MLXIP ELISA Kits)-155 regulation of SHIP represents a unique axis that regulates dendritic cells function in vivo.

  5. SHIP1 and Csk are part of the PSTPIP2-dependent inhibitory network that prevents the development of autoinflammatory disease.

  6. intracellular signaling by SHIP1 in mesenchymal stem cells is critical for hematopoiesis and lineage commitment during aging.

  7. Data show that 5'-inositol phosphatase SHIP1 deficiency extrinsically affects invariant NK (iNKT) cell proliferation.

  8. Selective deletion of Ship1 in T cells or dendritic cells impairs the formation of an adaptive TH2 response and protects animals from house dust mite-induced allergic airway inflammation.

  9. SHIP1 regulates mesenchymal stem cell numbers and their osteolineage commitment by limiting induction of the PI3K/Akt (show AKT1 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) pathways

  10. by promoting survival of protective T cells, thereby preventing an inflammatory myeloid response, SHIP1 maintains an appropriate balance of innate immune function at mucosal surfaces necessary for immune homeostasis.

Human Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) interaction partners

  1. SHIP levels and activity are lower in intestinal tissues and peripheral blood samples from patients with Crohn's disease, resulting in induction of Il1-beta (show IL1B ELISA Kits).

  2. Underexpression of SHIP1 is associated with drug resistance in acute myeloid leukemia (show BCL11A ELISA Kits).

  3. ectopically expressed SHIP1 accumulates in nucleolar cavities and colocalizes with the tumor suppressor protein p53 (show TP53 ELISA Kits).

  4. Results show that expression of SHIP1 protein is targeted by miR (show MLXIP ELISA Kits)-155 in acute myeloid leukemia (show BCL11A ELISA Kits) (AML (show RUNX1 ELISA Kits)) suggesting it as an onco-miR (show MLXIP ELISA Kits). The miR (show MLXIP ELISA Kits)-155/SHIP1/PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits) signaling pathway could play an important role in the pathogenesis of AML (show RUNX1 ELISA Kits).

  5. Overexpression of miR (show MLXIP ELISA Kits)-155 in the gouty synovial fluid mononuclear cells leads to suppress SHIP-1 levels and enhance proinflammatory cytokines.

  6. SLAMF7 (show SLAMF7 ELISA Kits)-triggered inhibition is mediated by a mechanism involving Src (show SRC ELISA Kits) kinases, CD45 (show PTPRC ELISA Kits), and SHIP-1 that is defective in MM cells

  7. The discovery and replication studies presented here show SHIP-1 to be a risk marker for acute ischemic stroke in the Chinese population, which appears to be a novel finding.

  8. High ship1 expression is associated with chronic lymphocytic leukemia.

  9. Tks5 is needed for breast carcinoma cell invadopodium precursor stabilization, where the phox homology (PX) domain of Tks5 interacts with PI(3,4)P2. SHIP2 (show INPPL1 ELISA Kits) arrival at the invadopodium precursor coincides with the onset of PI(3,4)P2 accumulation.

  10. Based on these observations, authors conclude that miR (show MLXIP ELISA Kits)-155 modulates the neuroinflammatory response during Japanese encephalitis virus infection via negative regulation of SHIP1 expression.

Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) Antigen Profile

Antigen Summary

This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with INPP5D

  • inositol polyphosphate-5-phosphatase, 145kDa (INPP5D) antibody
  • inositol polyphosphate-5-phosphatase, 145kDa (inpp5d) antibody
  • inositol polyphosphate 5-phosphatase (EHI_159880) antibody
  • inositol polyphosphate 5-phosphatase (EHI_153490) antibody
  • phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 (inpp5d) antibody
  • Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 (ship1) antibody
  • inositol polyphosphate-5-phosphatase D (Inpp5d) antibody
  • 13.t00027 antibody
  • 256.t00004 antibody
  • AI323613 antibody
  • hp51CN antibody
  • INPP5D antibody
  • s-SHIP antibody
  • SHIP antibody
  • SHIP-1 antibody
  • SHIP1 antibody
  • SIP-145 antibody

Protein level used designations for INPP5D

inositol polyphosphate-5-phosphatase, 145kDa , SH2 containing inositol phosphatase , phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 , phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1-like , SH2 domain-containing inositol 5'-phosphatase 1 , SH2 domain-containing inositol phosphatase 1 , SH2 domain-containing inositol-5'-phosphatase 1 , SHIP-1 , phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 , Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 , SH2 containing inositol phosphotase , SH2-containing inositol phosphatase SHIP , SIP-145 , Src homology 2 domain-containing inositol-5-phosphatase , inositol polyphosphate-5-phosphatase of 145 kDa , inositol polyphosphate-5-phosphatase, 145 kDa , p150Ship , Inositol polyphosphate-5-phosphatase 145 kDa , Inositol polyphosphate-5-phosphatase, 145 kDa , signaling inositol polyphosphate 5 phosphatase SIP-145

GENE ID SPECIES
424745 Gallus gallus
470683 Pan troglodytes
507329 Bos taurus
100021361 Monodelphis domestica
100400043 Callithrix jacchus
100446045 Pongo abelii
100464150 Ailuropoda melanoleuca
559103 Danio rerio
3404260 Entamoeba histolytica HM-1:IMSS
3410671 Entamoeba histolytica HM-1:IMSS
100064896 Equus caballus
100526019 Sus scrofa
100561031 Anolis carolinensis
399051 Xenopus laevis
100380693 Salmo salar
16331 Mus musculus
54259 Rattus norvegicus
3635 Homo sapiens
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