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The protein encoded by INPP5F is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. Additionally we are shipping INPP5F Antibodies (35) and INPP5F Proteins (3) and many more products for this protein.
we identified inositol polyphosphate-5-phosphatase F (INPP5F) as a prognostic factor for progression-free survival in Chronic lymphocytic leukemia
These findings suggest that INPP5F is a potential tumor suppressor in gliomas via inhibition of STAT3 pathway, and that deregulation of INPP5F may lead to contribution to gliomagenesis.
Sac2 colocalizes with early endosomal markers and is recruited to transferrin (show Tf ELISA Kits)-containing vesicles during endocytic recycling.
Inpp5f is a polyphosphoinositide phosphatase that regulates cardiac hypertrophic responsiveness.
Hyperglycemia and hyperlipidemia blunts the Insulin-Inpp5f negative feedback loop in the diabetic heart.
This study reveals Inpp5f (Sac2) as a novel suppressor of CNS axon repair after spinal cord injury
Sac2/INPP5F is a PI4P phosphatase that colocalizes with OCRL on endocytic membranes.
Inpp5f-v3 is specifically expressed in mouse brain, and may function in the development of mouse brain
A novel variant of Inpp5f is imprinted in brain, and its expression is correlated with differential methylation of an internal CpG island.
The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Sac domain-containing inositol phosphatase 2
, phosphatidylinositide phosphatase SAC2
, sac domain-containing phosphoinositide 5-phosphatase 2
, inositol polyphosphate 5-phosphatase F
, sac domain-containing inositol phosphatase 2