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Inositol Polyphosphate-5-Phosphatase K (INPP5K) ELISA Kits

INPP5K encodes a protein with 5-phosphatase activity toward polyphosphate inositol. Additionally we are shipping INPP5K Antibodies (26) and INPP5K Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat INPP5K INPP5K 287533  
Anti-Mouse INPP5K INPP5K 19062 Q8C5L6
Anti-Human INPP5K INPP5K 51763 Q9BT40
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More ELISA Kits for INPP5K Interaction Partners

Mouse (Murine) Inositol Polyphosphate-5-Phosphatase K (INPP5K) interaction partners

  1. the physiological role of Pak1 (show PAK1 ELISA Kits)-SKIP binding is in the regulation of insulin (show INS ELISA Kits) signaling in skeletal muscle

  2. SKIP controls the IGF-II-PI 3 (show PI3 ELISA Kits)-kinase-Akt (show AKT1 ELISA Kits)-mTOR (show FRAP1 ELISA Kits) auto-regulation loop during myogenesis.

  3. Specific suppression of insulin (show INS ELISA Kits) signaling is achieved via the spatiotemporal regulation of SKIP through the scaffolding function of Pak1 (show PAK1 ELISA Kits).

  4. Regulation of insulin signaling and glucose transporter 4 (GLUT4) exocytosis by phosphatidylinositol 3,4,5-trisphosphate (PIP3) phosphatase, skeletal muscle, and kidney enriched inositol polyphosphate phosphatase (SKIP).

  5. Results indicate that Inpp5k 5-phosphatase is important for the control of the arginine vasopressin (show AVP ELISA Kits)/aquaporin-2 (show AQP2 ELISA Kits) signalling pathway and water transport in kidney collecting ducts.

  6. Silencer of death domains (SODD (show BAG4 ELISA Kits)) inhibits skeletal muscle and kidney enriched inositol 5-phosphatase (SKIP) and regulates phosphoinositide 3-kinase (PI3K)/Akt (show AKT1 ELISA Kits) signaling to the actin cytoskeleton.

  7. Data shoe that the N-terminal domain of SifA is sufficient to interact with the pleckstrin (show PLEK ELISA Kits) homology domain of SKIP, forming a 1:1 complex with a micromolar dissociation constant.

  8. These results imply that SKIP regulates insulin (show INS ELISA Kits) signaling in skeletal muscle.

  9. results suggest that SKIP (skeletal muscle and kidney-enriched inositol phosphatase) plays a negative regulatory role in Akt (show AKT1 ELISA Kits)/ GSK-3beta/GS (glycogen synthase) pathway leading to glycogen (show GYS1 ELISA Kits) synthesis in myocytes

Human Inositol Polyphosphate-5-Phosphatase K (INPP5K) interaction partners

  1. SKIP controls the IGF-II-PI 3 (show PI3 ELISA Kits)-kinase-Akt (show AKT1 ELISA Kits)-mTOR (show FRAP1 ELISA Kits) auto-regulation loop during myogenesis.

  2. Specific suppression of insulin (show INS ELISA Kits) signaling is achieved via the spatiotemporal regulation of SKIP through the scaffolding function of Pak1 (show PAK1 ELISA Kits).

  3. The authors report that HBV core protein interacts with a cellular SKIP (skeletal muscle and kidney enriched inositol phosphatase) protein, an endoplasmic reticulum-located phosphoinositide 5-phosphatase, both in vivo and in vitro.

INPP5K Antigen Profile

Antigen Summary

This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with INPP5K

  • inositol polyphosphate-5-phosphatase K (Inpp5k) antibody
  • inositol polyphosphate-5-phosphatase K (INPP5K) antibody
  • inositol polyphosphate 5-phosphatase K (Inpp5k) antibody
  • C62 antibody
  • PPS antibody
  • SKIP antibody

Protein level used designations for INPP5K

C62 , inositol polyphosphate 5-phosphatase K , putative phosphoinositide 5-phosphatase type II , putative phosphoinositide 5-phosphatase type II; C62 , skeletal muscle and kidney enriched inositol phosphatase , PI-5-phosphatase related , putative PI-5-phosphatase , skeletal muscle and kidney enriched inositol polyphosphate phosphatase , skeletal muscle and kidney-enriched inositol phosphatase

GENE ID SPECIES
287533 Rattus norvegicus
454410 Pan troglodytes
514123 Bos taurus
19062 Mus musculus
51763 Homo sapiens
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