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anti-Inositol-Trisphosphate 3-Kinase B (ITPKB) Antibodies

The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. Additionally we are shipping ITPKB Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ITPKB 320404  
ITPKB 3707 P27987
ITPKB 54260 P42335
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Top anti-ITPKB Antibodies at antibodies-online.com

Showing 10 out of 53 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ELISA, WB ITPKB monoclonal antibody (M01), clone 2F8 Western Blot analysis of ITPKB expression in Jurkat . Western Blot analysis of ITPKB expression in transfected 293T cell line by ITPKB monoclonal antibody (M01), clone 2F8.Lane 1: ITPKB transfected lysate(67.4 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of ITPKB (arrow) using rabbit polyclonal ITPKB Antibody (R38) (ABIN652430). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ITPKB gene. ITPKB Antibody (N-term) (ABIN652430)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of ITPKB expression in HeLa (A), SP2/0 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of ITPKB expression in transfected 293T cell line by ITPKB monoclonal antibody (M01), clone 2F8. Lane 1: ITPKB transfected lysate(67.4 KDa). Lane 2: Non-transfected lysate. ITPKB monoclonal antibody (M01), clone 2F8 Western Blot analysis of ITPKB expression in Jurkat. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Alkaline Phosphatase (AP) FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated FACS, IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$375.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Mouse APC ELISA, WB   100 μL Log in to see 8 to 10 Days
$925.83
Details

ITPKB Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human ,
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Rat (Rattus)


Top referenced anti-ITPKB Antibodies

  1. Human Monoclonal ITPKB Primary Antibody for ELISA, WB - ABIN561565 : Nalaskowski, Fliegert, Ernst, Brehm, Fanick, Windhorst, Lin, Giehler, Hein, Lin, Mayr: Human inositol 1,4,5-trisphosphate 3-kinase isoform B (IP3KB) is a nucleocytoplasmic shuttling protein specifically enriched at cortical actin filaments and at invaginations of the nuclear envelope. in The Journal of biological chemistry 2011 (PubMed)

More Antibodies against ITPKB Interaction Partners

Mouse (Murine) Inositol-Trisphosphate 3-Kinase B (ITPKB) interaction partners

  1. Thus, non-canonical phosphoinositide 3-kinase-antagonism by Itpkb restricts pre-T cell receptor (show PTCRA Antibodies) induced metabolic activation to enforce coincidence-detection of pre-T cell receptor (show PTCRA Antibodies) expression and Notch (show NOTCH1 Antibodies)-engagement.

  2. These data identify Itpkb as an essential mediator of T cell activation and suggest Itpkb inhibition as a novel approach to treat autoimmune disease.

  3. Itpkb controls hematopoietic stem cell homeostasis and prevent death from severe anemia in mice.

  4. Itpkb controls survival, proliferation and cytokine production in mouse peripheral T cells.

  5. Data present the structure of the complete catalytic domain of inositol 1,4,5-trisphophate 3-kinase B, including the CaM (show Calm2 Antibodies) binding domain in complex with Mg(2 (show MCOLN1 Antibodies)+) and ATP.

  6. These data show that the absence of expression of the three isoenzymes of Itpk does not prevent the formation of IP5 and IP6 (show GPRIN2 Antibodies), at least in mouse embryonic fibroblasts.[Itpka (show ITPKA Antibodies), Itpkb, Itpkc (show ITPKC Antibodies)]

  7. Itpkb and inositol tetrakisphosphate mediate a survival signal in B cells.

  8. B cells from Itpkb(-/-) Ig hen (show RPS6 Antibodies) egg lysozyme (show LYZ Antibodies) mice possess an anergic phenotype, hypoproliferate in response to cognate Ag, and yet they exhibit enhanced Ag-induced calcium signaling

Human Inositol-Trisphosphate 3-Kinase B (ITPKB) interaction partners

  1. ITPKB is increased in Alzheimer's brain three-fold in the cerebral cortex of most patients with Alzheimer's disease compared with control subjects and accumulates in dystrophic neurites associated with amyloid plaques.

  2. a specific increase in inositol 1,4,5-trisphosphate 3-kinase A (show ITPKA Antibodies) and B (ITPKA (show ITPKA Antibodies) and ITPKB) was observed upon hESCs spontaneous differentiation.

  3. IP3KB not only regulates cytoplasmic Ca(2 (show CA2 Antibodies)+) signals by phosphorylation of subplasmalemmal and cytoplasmic Ins (show INS Antibodies)(1,4,5)P(3) but may also be involved in modulating nuclear Ca(2 (show CA2 Antibodies)+) signals generated from these nuclear envelope invaginations.

  4. results highlight the potential role of the three isoforms of InsP3 3-kinase as direct InsP3 metabolizing enzymes and direct regulators of Ca2 (show CA2 Antibodies)+ responses to extracellular signals

  5. We aim to summarize the existing information about functionally uncoupled IP(3)R (show ITPR1 Antibodies) and RyR (show RYR1 Antibodies) channels, and to discuss the concept that those channels can participate in Ca(2 (show CA2 Antibodies)+)-leak pathways.

  6. In each of the three isoforms a nuclear export signal has evolved in the catalytic domain either de novo (IP3K-A (show ITPKA Antibodies)) or as a substitute for an earlier evolved corresponding N-terminal signal (IP3K-B and IP3K-C (show ITPKC Antibodies)).

ITPKB Antigen Profile

Protein Summary

The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.

Gene names and symbols associated with ITPKB

  • inositol 1,4,5-trisphosphate 3-kinase B (Itpkb) antibody
  • inositol-trisphosphate 3-kinase B (ITPKB) antibody
  • inositol-trisphosphate 3-kinase B (itpkb) antibody
  • inositol 1,4,5-trisphosphate 3-kinase B (ITPKB) antibody
  • inositol-trisphosphate 3-kinase B (Itpkb) antibody
  • 1110033J02Rik antibody
  • E130307H12Rik antibody
  • IP3-3KB antibody
  • IP3K antibody
  • IP3K-B antibody
  • IP3KB antibody
  • PIG37 antibody
  • si:ch211-97m8.1 antibody

Protein level used designations for ITPKB

inositol-trisphosphate 3-kinase B , inositol 1,4,5-trisphosphate 3-kinase B , 1D-myo-inositol-trisphosphate 3-kinase B , inositol-trisphosphate 3-kinase B-like , IP3 3-kinase B , IP3K B , insP 3-kinase B , proliferation-inducing protein 37 , IP3K-B

GENE ID SPECIES
320404 Mus musculus
416743 Gallus gallus
457789 Pan troglodytes
490383 Canis lupus familiaris
540877 Bos taurus
563019 Danio rerio
698185 Macaca mulatta
100400613 Callithrix jacchus
100460190 Pongo abelii
100603824 Nomascus leucogenys
3707 Homo sapiens
54260 Rattus norvegicus
Selected quality suppliers for anti-ITPKB (ITPKB) Antibodies
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