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Insulin Receptor Substrate 4 (IRS4) ELISA Kits

IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Additionally we are shipping IRS4 Antibodies (38) and IRS4 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
IRS4 8471 O14654
IRS4 16370 Q9Z0Y7
Anti-Rat IRS4 IRS4 315350  
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Top IRS4 ELISA Kits at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human < 0.78 ng/mL 96 Tests Log in to see 11 to 13 Days
$875.60
Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
Details

More ELISA Kits for IRS4 Interaction Partners

Human Insulin Receptor Substrate 4 (IRS4) interaction partners

  1. The association of IRS4 with SSH1 (show SSH1 ELISA Kits) contributes to localized activation of cofilin (show CFL1 ELISA Kits) in membrane protrusions.

  2. Overexpression of IRS4 in U2OS cells activates PI3K (show PIK3CA ELISA Kits) signalling.

  3. We genotyped single-nucleotide polymorphisms of IGF1 (show IGF1 ELISA Kits), IGF2, IGF1R (show IGF1R ELISA Kits), IGF2R (show IGF2R ELISA Kits), IGFBP1 (show IGFBPI ELISA Kits), IGFBP3 (show IGFBP3 ELISA Kits), IGFBP5 (show IGFBP5 ELISA Kits), IRS1 (show IRS1 ELISA Kits), IRS2 (show IRS2 ELISA Kits), and IRS (show IARS ELISA Kits) in pancreatic cancer patients

  4. This study clearly demonstrates associations between body mass index and IRS-4 variants in schizophrenia patients, but not in healthy controls, pointing to a possible involvement of IRS-4 in the control of body weight in schizophrenia.

  5. Study for the first time identified IRS4 mutations in T-ALL.

  6. IRS-4 gene is not of importance for aetiology of the vast majority of schizophrenia cases, but a single patient with schizophrenia and a mutation in IRS-4 points to that the insulin (show INS ELISA Kits) signalling system is of interest in the search for schizophrenia genes

  7. The t(X;6) in subungual exostosis results in transcriptional deregulation of the gene for insulin receptor substrate 4.

  8. Insulin receptor substrate 4 associates with the protein IRAS (show NISCH ELISA Kits)

  9. IRS-4 does not function as a substrate of the insulin (show INS ELISA Kits) and the IGF-I receptor (show IGF1R ELISA Kits) in primary muscle cells but may be involved in nonreceptor tyrosine kinase (show TXK ELISA Kits) signaling.

  10. data demonstrate cell-specific alterations in IRS (show IARS ELISA Kits) protein concentrations in theca cells from polycystic ovaries consistent with exaggerated amplification of the insulin (show INS ELISA Kits) signal & which may play a role in ovarian hyperandrogenism & thecal hyperplasia

Mouse (Murine) Insulin Receptor Substrate 4 (IRS4) interaction partners

  1. conclude that Y103 is required for the internalization of hCTR1 (show SLC31A1 ELISA Kits) in response to Cu, that this occurs by a mechanism other than phosphorylation and that mutation of Y103 modulates the interaction with IRS-4

  2. Down-regulation of the insulin receptor substrate 4 (Irs4) gene, may be an important event in the transition from age-related changes to Alzheimer's disease specific-changes.

  3. These data suggest that IRS (show IARS ELISA Kits)-dependent signaling pathways work by recruiting different signaling molecules to determine specificity of IL-2R gamma (show IL2RG ELISA Kits) superfamily cytokines.

  4. These data indicate that both insulin receptor (show INSR ELISA Kits) substrate (IRS)-1 (show IRS1 ELISA Kits) and -3, but not IRS-2 (show IRS2 ELISA Kits) or IRS-4, play key roles in the differentiation of brown adipocytes.

  5. Data demonstrate that IRS4 interacts with the LR. This recruitment is leptin (show LEP ELISA Kits) dependent and requires phosphorylation of the Y1077 motif of the LR.

  6. Protein kinase C-zeta (show PRKCZ ELISA Kits) phosphorylates insulin receptor substrate-1 (show IRS1 ELISA Kits), -3, and -4 but not -2 (show CNOT2 ELISA Kits).

IRS4 Antigen Profile

Antigen Summary

IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation..

Gene names and symbols associated with IRS4

  • insulin receptor substrate 4 (IRS4) antibody
  • insulin receptor substrate 4 (irs4) antibody
  • insulin receptor substrate 4 (Irs4) antibody
  • IRS-4 antibody
  • irs2 antibody
  • irs2-a antibody
  • IRS4 antibody
  • PY160 antibody

Protein level used designations for IRS4

insulin receptor substrate 4 , 160 kDa phosphotyrosine protein , phosphoprotein of 160 kDa , pp160 , IRS-2-A , insulin receptor substrate 2-A , insulin receptor substrate protein , insulin receptor substrate-undetermined designation , insulin receptor substrate-unique , xIRS-u

GENE ID SPECIES
492059 Canis lupus familiaris
514607 Bos taurus
100196925 Xenopus (Silurana) tropicalis
8471 Homo sapiens
16370 Mus musculus
315350 Rattus norvegicus
399388 Xenopus laevis
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