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a mitogenic growth factor\; may have a role in fetal development [RGD, Feb 2006].. Additionally we are shipping IGF2 Kits (108) and IGF2 Proteins (64) and many more products for this protein.
Showing 10 out of 159 products:
Human Polyclonal IGF2 Primary Antibody for IP, IHC - ABIN1584589
Matsumoto, Harada, Saito, Taniguchi: Induction of insulin-like growth factor 2 expression in a mesenchymal cell line co-cultured with an ameloblast cell line. in In vitro cellular & developmental biology. Animal 2011
Show all 3 references for ABIN1584589
Human Polyclonal IGF2 Primary Antibody for FACS, IHC (p) - ABIN650616
Hsieh, Chang, Wang, Hsu, Chen, Hsu, Tsai: Insulin-like growth factors II exon 9 and E-cadherin-Pml I but not myeloperoxidase promoter-463, urokinase-ApaL I nor xeroderma pigmentosum polymorphisms are associated with higher susceptibility to leiomyoma. in Anticancer research 2010
Show all 2 references for ABIN650616
Human Monoclonal IGF2 Primary Antibody for ICC, FACS - ABIN1098108
El Tayebi, Salah, El Sayed, Salam, Zekri, Zayed, Salem, Esmat, Abdelaziz: Expression of insulin-like growth factor-II, matrix metalloproteinases, and their tissue inhibitors as predictive markers in the peripheral blood of HCC patients. in Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2011
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Human Polyclonal IGF2 Primary Antibody for EIA, FACS - ABIN952912
Adkins, Somes, Morrison, Hill, Watson, Magann, Krushkal: Association of birth weight with polymorphisms in the IGF2, H19, and IGF2R genes. in Pediatric research 2010
Igf2 regulates early neural and cardiovascular development in zebrafish embryos.
The IGF2 expression has also been reported at earlier stages in fish.
zebrafish orthologs of IGF2 function in dorsal midline development during segmentation/neurulation, whereas one paralog, igf2b, has evolved additional, distinct functions during subsequent organogenesis.
Data indicate that the effects of insulin-like growth factor 2 (IGF2) are mediated by direct upregulation of the cyclin-dependent kinase inhibitor p57 (p57 (show CDKN1C Antibodies)).
Mstn may negatively regulate Igf2 expression to control postnatal skeletal muscle growth, however differences in growth between male and female mice are not readily explained by changes in expression of Igf family members.
Study provides evidence for regulation of Igf2 by microRNAs and further elucidates the role of miR141-3p and miR (show MLXIP Antibodies)-200a-3p in the mouse placental development.
IGF2 contributes to neural stem cell maintenance in subventricular zone but not in the subgranular zone, and this is regulated by the biallelic expression of IGF2 in the vascular compartment.
results uncovered a distinctive pro-IGF-II-mediated self-reinforcement mechanism of muscle regeneration
Data (including data from studies in knockout mice) suggest that, in aging and metabolic stress such as insulin resistance/pregnancy, pancreatic beta-cells exhibit sex differences in expression of Igf2 during beta-cell expansion/mass adaptation.
case of Balb/3T3 the concentration of IGF2 in culture supernatants decreased after 1 and 5 mM and increased after 10 mM of metformin. metformin influences the cytophysiology of somatic cells causing inhibition of proliferation
ZBED6 inhibits IGF2 activity.
Insulator activity of the H19 (show NCKAP1 Antibodies)/Igf2 imprinting control region varies by cell type and may depend on cell-specific enhancers as well as posttranslational modifications of the insulator protein CTCF (show CTCF Antibodies).
upregulation of IGF2/Igf2 is likely controlled by hypermethylation of H19 DMR1 in human NTDs, however, in acute external RA-induced NTD mice it is potentially determined by more open chromatin structure
a mitogenic growth factor\; may have a role in fetal development
insulin-like growth factor II
, insulin-like growth factor 2
, insulin-like growth factor 2b
, insulin-like growth factor 2-A
, insulin-like growth factor II-A
, multiplication-stimulating polypeptide
, Insulin-like growth factor II (somatomedin A)
, insulin-like growth factor II (IGF-II)
, insulin-like growth factor II isoform 2 variant 4 preprotein
, multiplication-stimulating activity