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a mitogenic growth factor\; may have a role in fetal development [RGD, Feb 2006].. Additionally we are shipping IGF2 Kits (66) and IGF2 Proteins (46) and many more products for this protein.
Showing 10 out of 111 products:
Human Polyclonal IGF2 Primary Antibody for EIA, FACS - ABIN952912
Adkins, Somes, Morrison, Hill, Watson, Magann, Krushkal: Association of birth weight with polymorphisms in the IGF2, H19, and IGF2R genes. in Pediatric research 2010
Igf2 regulates early neural and cardiovascular development in zebrafish embryos.
The IGF2 expression has also been reported at earlier stages in fish.
zebrafish orthologs of IGF2 function in dorsal midline development during segmentation/neurulation, whereas one paralog, igf2b, has evolved additional, distinct functions during subsequent organogenesis.
Our study reveals that the expression level of Igf2 is critical to maintain the balance between stem cell self-renewal and differentiation, presumably by regulating the interaction between HSC (show FUT1 Antibodies) and their niche.
To test the tumorigenic potential of different cell types in the developing kidney, we used kidney progenitor-specific Cre recombinase alleles to introduce Wt1 and Ctnnb1 mutations, two alterations observed in Wilms tumor, into embryonic mouse kidney, with and without biallelic Igf2 expression, another alteration that is observed in a majority of tumors
This study demonstrated that the Decreased IDE and IGF2 expression in the cerebral cortex of pups by early life lead exposure.
analysis of the distal muscle enhancer in the mouse Igf2 locus
Data indicate that the effects of insulin-like growth factor 2 (IGF2) are mediated by direct upregulation of the cyclin-dependent kinase inhibitor p57 (p57 (show CDKN1C Antibodies)).
Mstn may negatively regulate Igf2 expression to control postnatal skeletal muscle growth, however differences in growth between male and female mice are not readily explained by changes in expression of Igf family members.
Study provides evidence for regulation of Igf2 by microRNAs and further elucidates the role of miR141-3p and miR (show MLXIP Antibodies)-200a-3p in the mouse placental development.
IGF2 contributes to neural stem cell maintenance in subventricular zone but not in the subgranular zone, and this is regulated by the biallelic expression of IGF2 in the vascular compartment.
results uncovered a distinctive pro-IGF-II-mediated self-reinforcement mechanism of muscle regeneration
Data (including data from studies in knockout mice) suggest that, in aging and metabolic stress such as insulin resistance/pregnancy, pancreatic beta-cells exhibit sex differences in expression of Igf2 during beta-cell expansion/mass adaptation.
a mitogenic growth factor\; may have a role in fetal development
insulin-like growth factor II
, insulin-like growth factor 2
, insulin-like growth factor 2b
, insulin-like growth factor 2-A
, insulin-like growth factor II-A
, multiplication-stimulating polypeptide
, Insulin-like growth factor II (somatomedin A)
, insulin-like growth factor II (IGF-II)
, insulin-like growth factor II isoform 2 variant 4 preprotein
, multiplication-stimulating activity