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Insulin-Like Growth Factor 2 Proteins (IGF2)

a mitogenic growth factor\; may have a role in fetal development [RGD, Feb 2006].. Additionally we are shipping IGF2 Antibodies (159) and IGF2 Kits (108) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IGF2 16002 P09535
IGF2 24483 P01346
IGF2    
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Top IGF2 Proteins at antibodies-online.com

Showing 10 out of 64 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated 25 μg Log in to see 10 to 12 Days
$135.88
Details
HOST_HEK-293 Cells Human Fc Tag 100 μg Log in to see 2 to 3 Days
$220.00
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 9 to 11 Days
$217.80
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$225.75
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   25 μg Log in to see 10 to 12 Days
$146.75
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 4 to 6 Days
$297.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 10 to 12 Days
$233.72
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$313.50
Details

IGF2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus) ,
,
Human , , , , ,
, , ,

Top referenced IGF2 Proteins

  1. Human IGF2 Protein expressed in Escherichia coli (E. coli) - ABIN2667447 : Church, Phillips, Stuckey, Barnes, Buffa, Manek, Clarke, Harris, Carter, Hassan: Igf2 ligand dependency of Pten(+/-) developmental and tumour phenotypes in the mouse. in Oncogene 2012 (PubMed)
    Show all 8 references for ABIN2667447

  2. Human IGF2 Protein expressed in Escherichia coli (E. coli) - ABIN2666836 : Liu, Wang, Han, Yang, Peng: A novel role of IGFBP7 in mouse uterus: regulating uterine receptivity through Th1/Th2 lymphocyte balance and decidualization. in PLoS ONE 2012 (PubMed)
    Show all 8 references for ABIN2666836

  3. Mouse (Murine) IGF2 Protein expressed in Escherichia coli (E. coli) - ABIN2666937 : Gardner, Alzhanov, Knollman, Kuninger, Rotwein: TGF-β inhibits muscle differentiation by blocking autocrine signaling pathways initiated by IGF-II. in Molecular endocrinology (Baltimore, Md.) 2011 (PubMed)
    Show all 7 references for ABIN2666937

  4. Human IGF2 Protein expressed in Escherichia coli (E. coli) - ABIN1047204 : Dull, Gray, Hayflick, Ullrich: Insulin-like growth factor II precursor gene organization in relation to insulin gene family. in Nature 1984 (PubMed)
    Show all 5 references for ABIN1047204

  5. Human IGF2 Protein expressed in Escherichia coli (E. coli) - ABIN413415 : Wang, Rayes, Elahi, Lu, Hancock, Massie, Rowe, Aomari, Hossain, Durocher, Pinard, Tabariès, Siegel, Brodt: The IGF-Trap: Novel Inhibitor of Carcinoma Growth and Metastasis. in Molecular cancer therapeutics 2015 (PubMed)

  6. Human IGF2 Protein expressed in HEK-293 Cells - ABIN2181264 : Storch, Kübler, Höning, Ackmann, Zapf, Blum, Braulke: Transferrin binds insulin-like growth factors and affects binding properties of insulin-like growth factor binding protein-3. in FEBS letters 2001 (PubMed)

More Proteins for Insulin-Like Growth Factor 2 (IGF2) Interaction Partners

Zebrafish Insulin-Like Growth Factor 2 (IGF2) interaction partners

  1. Igf2 regulates early neural and cardiovascular development in zebrafish embryos.

  2. The IGF2 expression has also been reported at earlier stages in fish.

  3. zebrafish orthologs of IGF2 function in dorsal midline development during segmentation/neurulation, whereas one paralog, igf2b, has evolved additional, distinct functions during subsequent organogenesis.

Mouse (Murine) Insulin-Like Growth Factor 2 (IGF2) interaction partners

  1. analysis of the distal muscle enhancer in the mouse Igf2 locus

  2. Data indicate that the effects of insulin-like growth factor 2 (IGF2) are mediated by direct upregulation of the cyclin-dependent kinase inhibitor p57 (p57 (show CDKN1C Proteins)).

  3. Mstn may negatively regulate Igf2 expression to control postnatal skeletal muscle growth, however differences in growth between male and female mice are not readily explained by changes in expression of Igf family members.

  4. Study provides evidence for regulation of Igf2 by microRNAs and further elucidates the role of miR141-3p and miR (show MLXIP Proteins)-200a-3p in the mouse placental development.

  5. IGF2 contributes to neural stem cell maintenance in subventricular zone but not in the subgranular zone, and this is regulated by the biallelic expression of IGF2 in the vascular compartment.

  6. results uncovered a distinctive pro-IGF-II-mediated self-reinforcement mechanism of muscle regeneration

  7. Data (including data from studies in knockout mice) suggest that, in aging and metabolic stress such as insulin resistance/pregnancy, pancreatic beta-cells exhibit sex differences in expression of Igf2 during beta-cell expansion/mass adaptation.

  8. case of Balb/3T3 the concentration of IGF2 in culture supernatants decreased after 1 and 5 mM and increased after 10 mM of metformin. metformin influences the cytophysiology of somatic cells causing inhibition of proliferation

  9. ZBED6 inhibits IGF2 activity.

  10. Insulator activity of the H19 (show NCKAP1 Proteins)/Igf2 imprinting control region varies by cell type and may depend on cell-specific enhancers as well as posttranslational modifications of the insulator protein CTCF (show CTCF Proteins).

IGF2 Protein Profile

Protein Summary

a mitogenic growth factor\; may have a role in fetal development

Gene names and symbols associated with IGF2

  • insulin-like growth factor II (LOC100136550)
  • insulin-like growth factor 2a (igf2a)
  • insulin-like growth factor 2 (somatomedin A) (igf2-a)
  • insulin-like growth factor 2 (somatomedin A) (IGF2)
  • insulin-like growth factor 2 (Igf2)
  • insulin-like growth factor 2 (somatomedin A) (Igf2)
  • AL033362 protein
  • Igf-2 protein
  • Igf-II protein
  • igf2 protein
  • igf2b protein
  • IGFII protein
  • insigf protein
  • LOC100136550 protein
  • M6pr protein
  • Mpr protein
  • Peg2 protein
  • pp9974 protein
  • RNIGF2 protein
  • wu:fc26e03 protein
  • zgc:91781 protein

Protein level used designations for IGF2

insulin-like growth factor II , etID31232.25 , insulin-like growth factor 2 , insulin-like growth factor 2b , IGF-II-A , insulin-like growth factor 2-A , insulin-like growth factor II-A , xIGF-2 , IGF-II , multiplication-stimulating polypeptide , Insulin-like growth factor II (somatomedin A) , MSA , insulin-like growth factor II (IGF-II) , insulin-like growth factor II isoform 2 variant 4 preprotein , multiplication-stimulating activity

GENE ID SPECIES
100136550 Salmo salar
30710 Danio rerio
398240 Xenopus laevis
100218445 Taeniopygia guttata
16002 Mus musculus
24483 Rattus norvegicus
100135552 Cavia porcellus
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