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The protein encoded by IGF2BP3 is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. Additionally we are shipping Insulin-Like Growth Factor 2 MRNA Binding Protein 3 Kits (14) and Insulin-Like Growth Factor 2 MRNA Binding Protein 3 Proteins (3) and many more products for this protein.
Showing 10 out of 56 products:
Human Monoclonal IGF2BP3 Primary Antibody for EIA, IHC (p) - ABIN1107679
Jeng, Chang, Hu, Chou, Kao, Wang, Hsu: RNA-binding protein insulin-like growth factor II mRNA-binding protein 3 expression promotes tumor invasion and predicts early recurrence and poor prognosis in hepatocellular carcinoma. in Hepatology (Baltimore, Md.) 2008
Human Monoclonal IGF2BP3 Primary Antibody for IHC, ELISA - ABIN969208
Sitnikova, Mendese, Liu, Woda, Lu, Dresser, Mohanty, Rock, Jiang: IMP3 predicts aggressive superficial urothelial carcinoma of the bladder. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008
IGF2BP3 regulated transcripts via targeting elements within 3' untranslated regions (3'UTR (show UTS2R Antibodies))
An isocorydine derivative (d-ICD (show GNPTAB Antibodies)) inhibits drug resistance by downregulating IGF2BP3 expression in hepatocellular carcinoma.
Data show that insulin-like growth factor-2 (show IGF2 Antibodies)-mRNA-binding proteins IGF2BP1 (show IGF2BP1 Antibodies), IGF2BP2 (show IGF2BP2 Antibodies), and IGF2BP3 are direct targets of microRNA-1275 (miR (show MLXIP Antibodies)-1275).
Our results provide insight into the link between regulation of KIF20A (show KIF20A Antibodies)-mediated trafficking of IGF2BP3-containing stress granules and modulation of the motility and invasiveness in pancreatic cancers.
IGF2BP3 and IGF2BP3-bound transcripts are localized in cytoplasmic RNA granules that accumulate in membrane protrusions of pancreatic cancer cells.
these findings suggest that IMP3 expression may be a prognostic indicator of squamous cell carcinoma.
IGF2BP3 was highly expressed in placental villi during early pregnancy, especially in cytotrophoblast cells and trophoblast column.
Data show that TTK protein kinase, lymphocyte antigen 6 complex locus K (show Ly6k Antibodies) and insulin (show INS Antibodies)-like growth factor (IGF)-II mRNA binding protein 3 are tumor-associated antigens recognized by cytotoxic T lymphocytes and HLA-A24 (show CD164 Antibodies)-restricted epitope peptides.
Our results suggest that IMP3 may be an ancillary tool in identifying aggressive abdominal mesenchymal tumors other than gastrointestinal stromal tumor.
The combination of IMP3 and GLUT1 (show SLC2A1 Antibodies) is most appropriate for distinguishing malignant mesothelioma from reactive mesothelial cells using formalin-fixed, paraffin-embedded sections.
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.
insulin-like growth factor 2 mRNA-binding protein 3
, insulin-like growth factor 2 mRNA binding protein 3
, insulin-like growth factor 2 mRNA-binding protein 3-like
, IGF II mRNA binding protein 3
, IGF-II mRNA-binding protein 3
, IGF2 mRNA-binding protein 3
, KH domain containing protein overexpressed in cancer
, KH domain-containing protein overexpressed in cancer
, VICKZ family member 3
, cancer/testis antigen 98
, insulin-like growth factor 2, binding protein 3
, Vg1 RBP
, decapentaplegic and Vg-related 1 RNA-binding protein
, decapentaplegic and Vg-related 1, RNA binding protein
, vg1 RNA-binding protein