Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
The protein encoded by IGF2BP3 is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. Additionally we are shipping Insulin-Like Growth Factor 2 MRNA Binding Protein 3 Antibodies (72) and Insulin-Like Growth Factor 2 MRNA Binding Protein 3 Kits (19) and many more products for this protein.
Showing 5 out of 5 products:
IGF2BP3 influences a malignancy-associated RNA regulon by modulating miRNA-mRNA interactions.
IGF2BP3 as a human ontogenic master switch that restricts megakaryocyte development by modulating a lineage-specific P-TEFb (show CCNT1 Proteins) activation mechanism.
Results suggest that IGF2BP3 promotes eIF4E-mediated translational activation through the reduction of EIF4E-BP2 via mRNA degradation, leading to enhanced cell proliferation.
We compressively revealed the oncogenic role of IGF2BP3 in gastric tumorigenesis and confirmed its activation is partly due to the silence of miR (show MLXIP Proteins)-34a. Our findings identified useful prognostic biomarker and provided clinical translational potential.
study showed that MEC (show CCL28 Proteins) seems to be more sensitive to IMP3 than ACC and provided an insight into this protein in salivary gland tumors. Furthermore, although IMP3 is not a specific diagnostic marker to distinguish the tumors studied, it seems to mediate cell adhesion and migration in these tumors
IMP3 may be a useful marker for predicting invasion in biliary tumors with intraductal papillary growth.
IGF2BP3 might play the most important role in tumor aggressiveness and prognosis in lung adenocarcinoma.
Data show that insulin-like growth factor II mRNA-binding protein (IMP3) expression was found to be associated with the presence of in situ carcinoma in mucinous borderline ovarian tumors (BOTs), but not in other subtypes.
IMP3 plays an important role in proliferation and in the invasion of cutaneous squamous cell carcinoma, and may be a suitable marker for the histopathological diagnosis of SCC (show CYP11A1 Proteins) with a crateriform architecture and keratoacanthoma
MicroRNA-129-1 acts as tumour suppressor and induces cell cycle arrest of GBM cancer cells through targeting IGF2BP3 and MAPK1 (show MAPK3 Proteins)
IGF2BP3 regulated transcripts via targeting elements within 3' untranslated regions (3'UTR)
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.
insulin-like growth factor 2 mRNA-binding protein 3
, insulin-like growth factor 2 mRNA binding protein 3
, insulin-like growth factor 2 mRNA-binding protein 3-like
, IGF II mRNA binding protein 3
, IGF-II mRNA-binding protein 3
, IGF2 mRNA-binding protein 3
, KH domain containing protein overexpressed in cancer
, KH domain-containing protein overexpressed in cancer
, VICKZ family member 3
, cancer/testis antigen 98
, insulin-like growth factor 2, binding protein 3
, Vg1 RBP
, decapentaplegic and Vg-related 1 RNA-binding protein
, decapentaplegic and Vg-related 1, RNA binding protein
, vg1 RNA-binding protein