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IGF2BP2 encodes a member of the IGF-II mRNA-binding protein (IMP) family. Additionally we are shipping IGF2BP2 Proteins (16) and IGF2BP2 Kits (1) and many more products for this protein.
Showing 10 out of 129 products:
Human Polyclonal IGF2BP2 Primary Antibody for EIA, IHC (p) - ABIN952834
Pechlivanis, Scherag, Mühleisen, Möhlenkamp, Horsthemke, Boes, Bröcker-Preuss, Mann, Erbel, Jöckel, Nöthen, Moebus,: Coronary artery calcification and its relationship to validated genetic variants for diabetes mellitus assessed in the Heinz Nixdorf recall cohort. in Arteriosclerosis, thrombosis, and vascular biology 2010
Show all 2 references for ABIN952834
Human Polyclonal IGF2BP2 Primary Antibody for ELISA, WB - ABIN564642
Boudoukha, Cuvellier, Polesskaya: Role of the RNA-binding protein IMP-2 in muscle cell motility. in Molecular and cellular biology 2010
Show all 2 references for ABIN564642
Human Polyclonal IGF2BP2 Primary Antibody for ELISA, WB - ABIN1451955
Muzny, Scherer, Kaul, Wang, Yu, Sudbrak, Buhay, Chen, Cree, Ding, Dugan-Rocha, Gill, Gunaratne, Harris, Hawes, Hernandez, Hodgson, Hume, Jackson, Khan, Kovar-Smith, Lewis, Lozado, Metzker et al.: The DNA sequence, annotation and analysis of human chromosome 3. ... in Nature 2006
Human Monoclonal IGF2BP2 Primary Antibody for FACS, IF - ABIN2453176
Schaeffer, Hansen, Morris, LeBoeuf, Abrass: RNA-binding protein IGF2BP2/IMP2 is required for laminin-?2 mRNA translation and is modulated by glucose concentration. in American journal of physiology. Renal physiology 2012
Human Polyclonal IGF2BP2 Primary Antibody for ELISA, WB - ABIN238651
Zeggini, Weedon, Lindgren, Frayling, Elliott, Lango, Timpson, Perry, Rayner, Freathy, Barrett, Shields, Morris, Ellard, Groves, Harries, Marchini, Owen, Knight, Cardon, Walker, Hitman, Morris, Doney et al.: Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. ... in Science (New York, N.Y.) 2007
Study conclude that integration of genomic and transcriptomic data implicate circulating IGF2BP2 mRNA levels associated with glucose and insulin (show INS Antibodies) homeostasis
IGF2BP2 as a post-transcriptional regulatory mRNA-binding factor that contributes to Colorectal carcinogenesis.
p62/IMP2 stimulates cell migration and reduces cell adhesion, contributing to breast cancer progression.
IMP2 (show IMPA2 Antibodies) expression is higher in ovarian and endometrial high-grade serous carcinomas (HGSC) than in ovarian or endometrial endometrioid carcinoma. Knockdown in ovarian HGSC cell line decreased cell proliferation.
Our results suggest IGF2BP2 and KCNQ1 (show KCNQ1 Antibodies) polymorphisms might be independent predictors of chemotherapeutic response
HPV16 Down-Regulates the Insulin-Like Growth Factor Binding Protein 2 (show IGFBP2 Antibodies) to Promote Epithelial Invasion
Imp2 (show IMPA2 Antibodies) regulates the activity of IGF2, which further activates PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling.
Data show that insulin-like growth factor-2 (show IGF2 Antibodies)-mRNA-binding proteins IGF2BP1 (show IGF2BP1 Antibodies), IGF2BP2, and IGF2BP3 (show IGF2BP3 Antibodies) are direct targets of microRNA-1275 (miR (show MLXIP Antibodies)-1275).
The IGF2BP2 gene rs1470579 and rs4402960 polymorphisms were associated with type 2 diabetes patients and therapeutic efficacy of pioglitazone in this Chinese population
The IGF2BP2 gene rs4402960 polymorphism increases the breast cancer risk of Chinese females with Han nationality, and is a breast cancer predisposing gene.
p62/IMP2 promotes hepatocarcinogenesis by an amplification of inflammation.
IGF2BP2/IMP2-Deficient mice resist obesity through enhanced translation of Ucp1 (show UCP1 Antibodies) mRNA and Other mRNAs encoding mitochondrial proteins.
p62/IGF2BP2-2 drives the progression of NAFLD (show TSC2 Antibodies) through elevation of hepatic iron deposition and increased production of hepatic free cholesterol.
Mice with a liver overexpression of insulin-like growth factor 2 (IGF2 (show IGF2 Antibodies)) mRNA-binding protein p62/IMP2-2/IGF2BP2-2 show elevated Ccl2 (show CCL2 Antibodies) levels, which models all stages of non-alcoholic fatty liver disease.
data demonstrate that the HMGA2-IGF2BP2 axis functions as a key regulator of satellite cell activation and therefore skeletal muscle development
oncofetal insulin-like growth factor 2 mRNA-binding protein 2 (IMP2, IGF2BP2) regulates oxidative phosphorylation (OXPHOS) in primary glioblastoma (GBM) sphere cultures (gliomaspheres)
Dual phosphorylation of IMP2 at the mTOR sites is evident in the mouse embryo, likely coupling nutrient sufficiency to IGF2 expression and fetal growth
This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
IGF-II mRNA-binding protein 2
, IGF2 mRNA-binding protein 2
, VICKZ family member 2
, hepatocellular carcinoma autoantigen p62
, insulin-like growth factor 2 mRNA-binding protein 2
, insulin-like growth factor 2, binding protein 2