Insulin-Like Growth Factor 2 MRNA Binding Protein 3 Proteins (IGF2BP3)

The protein encoded by IGF2BP3 is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. Additionally we are shipping Insulin-Like Growth Factor 2 MRNA Binding Protein 3 Antibodies (70) and Insulin-Like Growth Factor 2 MRNA Binding Protein 3 Kits (17) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IGF2BP3 10643 O00425
IGF2BP3 140488 Q9CPN8
Rat IGF2BP3 IGF2BP3 312320  
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Top Insulin-Like Growth Factor 2 MRNA Binding Protein 3 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see 16 Days
$259.00
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HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$333.33
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HOST_Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Log in to see 15 to 18 Days
$736.00
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IGF2BP3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Insulin-Like Growth Factor 2 MRNA Binding Protein 3 (IGF2BP3) Interaction Partners

Human Insulin-Like Growth Factor 2 MRNA Binding Protein 3 (IGF2BP3) interaction partners

  1. IGF2BP3 as a human ontogenic master switch that restricts megakaryocyte development by modulating a lineage-specific P-TEFb (show CCNT1 Proteins) activation mechanism.

  2. Results suggest that IGF2BP3 promotes eIF4E-mediated translational activation through the reduction of EIF4E-BP2 via mRNA degradation, leading to enhanced cell proliferation.

  3. We compressively revealed the oncogenic role of IGF2BP3 in gastric tumorigenesis and confirmed its activation is partly due to the silence of miR (show MLXIP Proteins)-34a. Our findings identified useful prognostic biomarker and provided clinical translational potential.

  4. study showed that MEC (show CCL28 Proteins) seems to be more sensitive to IMP3 than ACC and provided an insight into this protein in salivary gland tumors. Furthermore, although IMP3 is not a specific diagnostic marker to distinguish the tumors studied, it seems to mediate cell adhesion and migration in these tumors

  5. IMP3 may be a useful marker for predicting invasion in biliary tumors with intraductal papillary growth.

  6. IGF2BP3 might play the most important role in tumor aggressiveness and prognosis in lung adenocarcinoma.

  7. Data show that insulin-like growth factor II mRNA-binding protein (IMP3) expression was found to be associated with the presence of in situ carcinoma in mucinous borderline ovarian tumors (BOTs), but not in other subtypes.

  8. IMP3 plays an important role in proliferation and in the invasion of cutaneous squamous cell carcinoma, and may be a suitable marker for the histopathological diagnosis of SCC (show CYP11A1 Proteins) with a crateriform architecture and keratoacanthoma

  9. MicroRNA-129-1 acts as tumour suppressor and induces cell cycle arrest of GBM cancer cells through targeting IGF2BP3 and MAPK1 (show MAPK3 Proteins)

  10. IGF2BP3 regulated transcripts via targeting elements within 3' untranslated regions (3'UTR)

Mouse (Murine) Insulin-Like Growth Factor 2 MRNA Binding Protein 3 (IGF2BP3) interaction partners

  1. IGF2BP3 regulated transcripts via targeting elements within 3' untranslated regions (3'UTR)

Insulin-Like Growth Factor 2 MRNA Binding Protein 3 (IGF2BP3) Protein Profile

Protein Summary

The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.

Gene names and symbols associated with IGF2BP3

  • insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3)
  • insulin-like growth factor 2 mRNA binding protein 3 (igf2bp3)
  • insulin-like growth factor 2 mRNA binding protein 3 (LOC100231176)
  • insulin-like growth factor 2 mRNA binding protein 3 (Igf2bp3)
  • 2610101N11Rik protein
  • AA522010 protein
  • Ab2-255 protein
  • AL022933 protein
  • AU045931 protein
  • CT98 protein
  • dvr1rbp protein
  • IMP-3 protein
  • IMP3 protein
  • KOC1 protein
  • Koc13 protein
  • mimp3 protein
  • Neilsen protein
  • RGD1306512 protein
  • vera protein
  • vg1rbp protein
  • VICKZ3 protein
  • wu:fb79c12 protein
  • wu:fe06h09 protein
  • zVg1RBP protein

Protein level used designations for IGF2BP3

insulin-like growth factor 2 mRNA-binding protein 3 , insulin-like growth factor 2 mRNA binding protein 3 , insulin-like growth factor 2 mRNA-binding protein 3-like , IGF II mRNA binding protein 3 , IGF-II mRNA-binding protein 3 , IGF2 mRNA-binding protein 3 , KH domain containing protein overexpressed in cancer , KH domain-containing protein overexpressed in cancer , VICKZ family member 3 , cancer/testis antigen 98 , hKOC , insulin-like growth factor 2, binding protein 3 , mIMP-3 , IMP-3 , Vg1 RBP , decapentaplegic and Vg-related 1 RNA-binding protein , decapentaplegic and Vg-related 1, RNA binding protein , vg1 RNA-binding protein , vg1-RBP

GENE ID SPECIES
539650 Bos taurus
549893 Xenopus (Silurana) tropicalis
704774 Macaca mulatta
744246 Pan troglodytes
100231176 Taeniopygia guttata
100394155 Callithrix jacchus
100602302 Nomascus leucogenys
10643 Homo sapiens
482357 Canis lupus familiaris
140488 Mus musculus
312320 Rattus norvegicus
420617 Gallus gallus
30967 Danio rerio
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