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Integrator Complex Subunit 6 Proteins (INTS6)

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. Additionally we are shipping Integrator Complex Subunit 6 Antibodies (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
INTS6 54606 Q9NY93
INTS6 18130 Q6PCM2
Rat INTS6 INTS6 361057  
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Top Integrator Complex Subunit 6 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

INTS6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Integrator Complex Subunit 6 (INTS6) Interaction Partners

Human Integrator Complex Subunit 6 (INTS6) interaction partners

  1. DICE1 appears to be involved in prostate cancer progression rather than in the initiation of prostate cancer.

  2. Findings demonstrate INTS6P1 and INTS6 exert the tumor suppressive roles through competing for oncomiR-17-5p.

  3. In response to the DNA damage response, INTS3 (show INTS3 Proteins)-hSSB1 (show SSBP1 Proteins)-INTS6 complex relocates to the DNA damage sites.

  4. Findings suggest that EBV encoded miR (show MLXIP Proteins)-BART3* miRNA targets DICE1 tumor suppressor to promote cellular growth and transformation in nasopharyngeal cancer(NPC (show NPC1 Proteins)).

  5. The helicase activity of DDX56 (show DDX56 Proteins) is required for its role in assembly of infectious West Nile virus particles.

  6. Coimmunoprecipitation confirmed that capsid protein binds to human DDX56 (show DDX56 Proteins) in infected cells and that this interaction is required for assembly of infectious West Nile virus particles.

  7. Somatic mutations were identified in three patients (3/56, 5%), and one novel polymorphism was identified in 3% of ESCC patients (4/136) and 3% of healthy individuals (6/232). We conclude that DICE1 mutations occur in ESCC but are infrequent.

  8. DICE1 has a growth-suppressing activity and interferes with anchorage-independent growth of IGF-IR transformed tumor cells dependent upon IGF-I (show IGF1 Proteins) signaling

  9. DDX26 maps to7p12, a region of frequent chromosome amplifications in glioblastoma involving the EGFR (show EGFR Proteins) gene.

Zebrafish Integrator Complex Subunit 6 (INTS6) interaction partners

  1. Our results are consistent with a novel role for Ints6 in restricting the vertebrate organizer to a dorsal domain in embryonic patterning.

Integrator Complex Subunit 6 (INTS6) Protein Profile

Protein Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with INTS6

  • integrator complex subunit 6 (INTS6)
  • integrator complex subunit 6 (LOC100339344)
  • integrator complex subunit 6 (ints6-b)
  • integrator complex subunit 6 (Tsp_09465)
  • DEAD (Asp-Glu-Ala-Asp) box helicase 56 (DDX56)
  • integrator complex subunit 6 (Ints6)
  • integrator complex subunit 6 (ints6)
  • 2900075H24Rik protein
  • AI480962 protein
  • DBI-1 protein
  • DDX21 protein
  • Ddx26 protein
  • DDX26A protein
  • DICE1 protein
  • HDB protein
  • INT6 protein
  • INTS6 protein
  • ints6-b protein
  • LRRGT00024 protein
  • NOH61 protein
  • Notch2l protein
  • Notchl2 protein

Protein level used designations for INTS6

integrator complex subunit 6 , integrator complex subunit 6-like , int6-B , integrator complex subunit 6-B , 61-kd nucleolar helicase , ATP-dependent 61 kDa nucleolar RNA helicase , DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 , DEAD box protein 21 , DEAD box protein 56 , DEAD-box RNA helicase , nucleolar helicase of 61 kDa , probable ATP-dependent RNA helicase DDX56 , putative nucleolar RNA helicase , DEAD box protein , DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26 , RNA helicase HDB , protein deleted in cancer 1 , DBI-1 , int6

GENE ID SPECIES
418876 Gallus gallus
452729 Pan troglodytes
476905 Canis lupus familiaris
100021987 Monodelphis domestica
100053346 Equus caballus
100082814 Ornithorhynchus anatinus
100156695 Sus scrofa
100339344 Oryctolagus cuniculus
100376905 Saccoglossus kowalevskii
100446137 Pongo abelii
100470508 Ailuropoda melanoleuca
495417 Xenopus laevis
10902733 Trichinella spiralis
100164318 Acyrthosiphon pisum
100542003 Meleagris gallopavo
54606 Homo sapiens
26512 Homo sapiens
18130 Mus musculus
361057 Rattus norvegicus
509695 Bos taurus
569456 Danio rerio
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