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anti-Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) (ITGA4) Antibodies

mouse homolog is involved in adult hematopoietic cell homeostasis, regeneration, and homing. Additionally we are shipping Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) Proteins (7) and Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ITGA4 16401 Q00651
ITGA4 311144  
ITGA4 3676 P13612
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Top anti-Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) Antibodies at antibodies-online.com

Showing 10 out of 468 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rat Biotin FACS, IHC (fro) Rat anti CD49d (Integrin alpha 4 chain) R1-2 0.1 mg Log in to see 6 to 8 Days
$253.00
Details
Mouse Rat PE FACS Staining of mouse peripheral blood lymphocytes with RAT ANTI MOUSE CD49d:RPE (ABIN119962). 100 Tests Log in to see 6 to 8 Days
$379.50
Details
Mouse Rat FITC FACS Rat anti CD49d (Integrin alpha 4 chain) R1-2 0.3 mg Log in to see 6 to 8 Days
$478.50
Details
Human Rat FITC FACS Staining of mouse peripheral blood lymphocytes with RAT ANTI MOUSE CD49d: FITC (ABIN119958). 0.1 mg Log in to see 6 to 8 Days
$253.00
Details
Mouse Rat Un-conjugated Func, FACS, IHC (fro), IP Cell Source: TK1 cell line.,.Percentage of cells stained above control: 99.6% 0.25 mg Log in to see 6 to 8 Days
$346.50
Details
Mouse Rat Un-conjugated FACS, IHC (fro) Staining of mouse peripheral blood lymphocytes with RAT ANTI MOUSE CD49d (ABIN119961). 0.1 mg Log in to see 6 to 8 Days
$253.00
Details
Human Mouse FITC FACS Staining of human peripheral blood lymphocytes with Mouse anti human CD49d - FITC(ABIN118708). 0.1 mg Log in to see 6 to 8 Days
$412.50
Details
Human Mouse PE FACS Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD49d:RPE (ABIN118712). 100 Tests Log in to see 6 to 8 Days
$456.50
Details
Human Mouse Un-conjugated FACS Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD49d (ABIN118710). 0.2 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rat Un-conjugated FACS, IHC (fro), IP Staining of mouse peripheral blood lymphocytes with RAT ANTI MOUSE CD49d 0.1 mg Log in to see 6 to 8 Days
$253.00
Details

ITGA4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) Antibodies

  1. Mouse (Murine) Monoclonal ITGA4 Primary Antibody for FACS, IHC (fro) - ABIN114224 : Holzmann, McIntyre, Weissman: Identification of a murine Peyer's patch--specific lymphocyte homing receptor as an integrin molecule with an alpha chain homologous to human VLA-4 alpha. in Cell 1989 (PubMed)
    Show all 3 references for ABIN114224

  2. Human Monoclonal ITGA4 Primary Antibody for FACS - ABIN118708 : Letarte, Seehafer, Greaves, Masellis-Smith, Shaw: Homotypic aggregation of pre-B leukemic cell lines by antibodies to VLA integrins correlates with their expression of CD9. in Leukemia 1993 (PubMed)
    Show all 3 references for ABIN118708

  3. Mouse (Murine) Monoclonal ITGA4 Primary Antibody for FACS - ABIN114227 : Holzmann, Weissman: Peyer's patch-specific lymphocyte homing receptors consist of a VLA-4-like alpha chain associated with either of two integrin beta chains, one of which is novel. in The EMBO journal 1989 (PubMed)
    Show all 3 references for ABIN114227

  4. Human Monoclonal ITGA4 Primary Antibody for FACS, IHC (fro) - ABIN118228 : Miyake, Medina, Ishihara, Kimoto, Auerbach, Kincade: A VCAM-like adhesion molecule on murine bone marrow stromal cells mediates binding of lymphocyte precursors in culture. in The Journal of cell biology 1991 (PubMed)
    Show all 3 references for ABIN118228

  5. Human Monoclonal ITGA4 Primary Antibody for FACS - ABIN118712 : Quackenbush, Letarte: Identification of several cell surface proteins of non-T, non-B acute lymphoblastic leukemia by using monoclonal antibodies. in Journal of immunology (Baltimore, Md. : 1950) 1985 (PubMed)
    Show all 2 references for ABIN118712

  6. Mouse (Murine) Monoclonal ITGA4 Primary Antibody for Func, FACS - ABIN114228 : Berlin, Berg, Briskin, Andrew, Kilshaw, Holzmann, Weissman, Hamann, Butcher: Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1. in Cell 1993 (PubMed)

  7. Mouse (Murine) Monoclonal ITGA4 Primary Antibody for FACS - ABIN119962 : Kinashi, Springer: Adhesion molecules in hematopoietic cells. in Blood cells 1995 (PubMed)

More Antibodies against Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) Interaction Partners

Mouse (Murine) Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) (ITGA4) interaction partners

  1. These results suggest that Tie2 (show TEK Antibodies) signaling induces alpha4beta1 integrin activation on bone marrow-mast cell progenitor for adhesion to VCAM-1 (show VCAM1 Antibodies).

  2. ITGA4 expression enhances metastasis in MYCN (show MYCN Antibodies) low neuroblastoma (show ARHGEF16 Antibodies).

  3. CD49d-high-expressing Th1 (show HAND1 Antibodies) memory phenotype CD4 (show CD4 Antibodies)+ T cells with enhanced B cell helper activity develop early in the peritoneal cavity.

  4. Data suggest that bortezomib mobilizes hematopoietic stem cells (HSPCs) by modulation of the integrin alpha4beta1 (VLA)-4/vascular cell adhesion molecule-1 (VCAM-1 (show VCAM1 Antibodies)) axis.

  5. Consistent with a role of alpha4beta7 in the generation of intestinal mononuclear phagocytes, bone marrow cells from beta7(-/-) mice poorly reconstituted small intestine retinoic acid (RA)-producing CD11c (show ITGAX Antibodies)(hi) dendritic cells.

  6. SP/drug efflux functionality of hematopoietic progenitors is controlled by mesenchymal niche through VLA-4/CD44 (show CD44 Antibodies) axis.

  7. We conclude that integrin alpha4beta1 is necessary for CD4 (show CD4 Antibodies)(+) T cell-mediated protection against C. trachomatis infection in the genital mucosa.

  8. Mobilization of bone marrow-derived cells by G-CSF (show CSF3 Antibodies) boosted migration along the VCAM-1 (show VCAM1 Antibodies)/VLA-4 axis and reduced apoptosis of cardiomyocytes.

  9. PI3-kinase gamma (show PIK3CG Antibodies) promotes Rap1a (show RAP1A Antibodies)-mediated activation of myeloid cell integrin alpha4beta1, leading to tumor inflammation and growth.

  10. alpha(4) and alpha(9) integrins interacting with OPN (show SPP1 Antibodies) via the SLAYGLR domain play a key role in macrophage biology by regulating migration, survival, and accumulation.

Human Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) (ITGA4) interaction partners

  1. Enhanced susceptibility of activated endocervical CD4 (show CD4 Antibodies)+ T cells to HIV may be related to increased CCR5 (show CCR5 Antibodies) expression by these cell subsets, but did not appear to be due to direct interaction of integrins a4b7 or a4b1 with HIV envelope.

  2. knockdown of PTTG1 (show PTTG1 Antibodies) increased expression of integrin alpha 4 (ITGA4), ITGA5 (show ITGA5 Antibodies), and integrin beta 1 (ITGB1 (show ITGB1 Antibodies)); otherwise, RhoA (show RHOA Antibodies) expression was significantly decreased

  3. Integrin alpha 2 (show ITGA2 Antibodies) and alpha 4 Yxxphi motifs interact with the endocytic clathrin adaptor, AP2 complex (show AP2B1 Antibodies).

  4. ITGA4 expression enhances metastasis in MYCN (show MYCN Antibodies) low neuroblastoma (show ARHGEF16 Antibodies).

  5. Data show that a small molecule inhibitor of the MYC (show MYC Antibodies) transcription factor can be an effective anticancer agent when delivered using a integrin alphavbeta3 (show ITGAV Antibodies) and VLA-4-targeted nanotherapy approach.

  6. Collectively, these data suggest a role for alpha4beta7 integrin in HIV infection that is influenced by both viral and host factors including the sequence of the HIV gp120 (show ITIH4 Antibodies) alpha4beta7 binding motif, the cytokine milieu and bacterial vaginosis in the genital tract.

  7. CD49d and CD26 (show DPP4 Antibodies) have independent prognostic value and we suggest its use as a part of routine panel for prognostic stratification of CLL.

  8. Hypermethylation of ITGA4 promoter is increased in inflamed colon tissue.

  9. Regulatory CD4 (show CD4 Antibodies) T cells (Treg) cells in co-infected patients present phenotypic alterations and might have dysfunction marked by low expression of Foxp3 (show FOXP3 Antibodies) and increased expression of molecules not frequently seen on Treg cells, such as CD49d.

  10. High VLA-4 expression was independently associated with a high probability of complete remission in acute myeloid leukemia (show BCL11A Antibodies) patients.

Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) (ITGA4) Antigen Profile

Protein Summary

The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain.

Gene names and symbols associated with ITGA4

  • integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (LOC100219853) antibody
  • integrin alpha 4 (Itga4) antibody
  • integrin, alpha 4 (Itga4) antibody
  • integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (ITGA4) antibody
  • CD49D antibody
  • IA4 antibody
  • LOC100219853 antibody

Protein level used designations for ITGA4

CD49 antigen-like family member D , LPAM subunit alpha , VLA-4 receptor, alpha 4 subunit , VLA-4 subunit alpha , integrin alpha-4 , integrin alpha-IV , lymphocyte Peyer patch adhesion molecules subunit alpha , 269C wild type , antigen CD49D, alpha-4 subunit of VLA-4 receptor , integrin alpha 4 , integrin alpha-4 subunit , very late activation protein 4 receptor, alpha 4 subunit

GENE ID SPECIES
100219853 Taeniopygia guttata
16401 Mus musculus
311144 Rattus norvegicus
3676 Homo sapiens
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