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Integrin, alpha 7 (ITGA7) Proteins (174869)

The protein encoded by 174869 belongs to the integrin alpha chain family. Additionally we are shipping Integrin, alpha 7 (ITGA7) Antibodies (66) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
174869 16404  
174869 3679 Q13683
Rat 174869 174869 81008 Q63258
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Top Integrin, alpha 7 (ITGA7) Proteins at antibodies-online.com

Showing 5 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

174869 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , ,
, ,

More Proteins for Integrin, alpha 7 (ITGA7) (174869) Interaction Partners

Mouse (Murine) Integrin, alpha 7 (ITGA7) (174869) interaction partners

  1. Sarcospan-mediated amelioration of muscular dystrophy in mouse model is dependent on the presence of both utrophin and alpha7beta1 integrin.

  2. loss of alpha7 integrin exacerbates a newly discovered muscle phenotype in sarcospan (show SSPN Proteins)-null mice

  3. Integrin alpha 7 integrin beta1 confers a protective effect in dystrophic muscle through the activation of the ILK (show ILK Proteins), AKT (show AKT1 Proteins), p70S6K (show RPS6KB1 Proteins) and BAD signaling to promote muscle cell survival.

  4. Up-regulation of integrin alpha 7 expression mediated by TGF-beta 1 (show TGFB1 Proteins) plays a role in the intraepithelial location of mucosal mast cells in vivo.

  5. the interaction of c-Myc (show MYC Proteins) with the promoter region of Itga7 is an important regulatory element controlling alpha7 integrin expression during muscle development and myotendinous (show TNC Proteins) junction formation

  6. FHL2 (show FHL2 Proteins) and FHL3 (show FHL3 Proteins), respectively, are colocalized with alpha(7)beta(1) integrin receptor at the periphery of Z-discs, suggesting a role in mechanical stabilization of muscle cells

  7. sarcoglycan (show SGCD Proteins) and integrin alpha7beta1 have overlapping roles in mediating cytoskeletal-membrane-extracellular matrix interaction

  8. Increased in vitro binding of integrin alpha7beta1 to laminin after ADP-ribosylation of the 37-kDa fragment of alpha7 requires the presence of Mn2+ and it is not observed in the presence of Mg2 (show MCOLN1 Proteins)+

  9. deltaEF1 has a role in suppressing integrin alpha 7 expression in myoblasts by displacing MYOD (show MYOD1 Proteins) and competing for p300/CBP (show CREBBP Proteins) co-activator

  10. An essential role is indicated for integrin alpha 7 in the maintenance of dystrophin (show DMD Proteins)-deficient muscles.

Human Integrin, alpha 7 (ITGA7) (174869) interaction partners

  1. Taken together, these results further support the use of a7 integrin as a potential therapy for Duchenne muscular dystrophy (show DMD Proteins)

  2. Data indicate that S100 calcium binding protein P (S100P (show S100P Proteins)) increased lung cancer cell migration by binding integrin alpha7.

  3. Data suggest that ITGA7 is an epigenetically regulated tumour suppressor gene and a prognostic factor in human malignant pleural mesothelioma.

  4. ITGA7 binds to tissue inhibitor of metalloproteinase 3 (TIMP3 (show TIMP3 Proteins)) in prostate cancer cells.

  5. Digenic mutational inheritance of the integrin alpha 7 and the myosin heavy chain 7B genes causes congenital myopathy with left ventricular non-compact cardiomyopathy. [ITGA7]

  6. Alpha7beta1D integrin modifies Ca2 (show CA2 Proteins)+ regulatory pathways and offers a means to protect the myocardium from ischemic injury.

  7. This report provides a novel insight into the mechanism, involving interaction with high temperature requirement A2, by which ITGA7 acts as a tumor suppressor.

  8. ILK (show ILK Proteins) interaction with MCM7 (show MCM7 Proteins) and MCM7 (show MCM7 Proteins) phosphorylation may be a critical event in ITGA7 signaling pathway, leading to tumor suppression.

  9. conclude that secondary integrin alpha 7 deficiency is rather common in muscular dystrophy/myopathy of unknown etiology

  10. FHL2 (show FHL2 Proteins) and FHL3 (show FHL3 Proteins), respectively, are colocalized with alpha(7)beta(1) integrin receptor at the periphery of Z-discs, suggesting a role in mechanical stabilization of muscle cells

Integrin, alpha 7 (ITGA7) (174869) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene names and symbols associated with 174869

  • integrin alpha 7 (Itga7)
  • integrin, alpha 7 (ITGA7)
  • integrin, alpha 7 (Itga7)
  • alpha7 protein
  • [a]7 protein

Protein level used designations for 174869

integrin alpha-7 , integrin alpha 7 chain , H36-alpha7 , alpha 7A integrin

GENE ID SPECIES
16404 Mus musculus
3679 Homo sapiens
81008 Rattus norvegicus
481097 Canis lupus familiaris
506953 Bos taurus
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