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Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) Proteins (ITGAE)

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Additionally we are shipping ITGAE Antibodies (348) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ITGAE 16407 Q60677
Rat ITGAE ITGAE 83577  
ITGAE 3682 P38570
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Top ITGAE Proteins at antibodies-online.com

Showing 8 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$952.01
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ITGAE Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
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Human , , ,
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More Proteins for Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE) Interaction Partners

Mouse (Murine) Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE) interaction partners

  1. Antigen-specific cytotoxic T lymphocytes target airway CD103+ and CD11b (show ITGAM Proteins)+ dendritic cells to suppress allergic inflammation.

  2. CD103 on FoxP3 (show FOXP3 Proteins)+ Treg cells was involved in Treg retention to inflamed skin.

  3. Interleukin-12-producing CD103+ CD11b (show ITGAM Proteins)- CD8 (show CD8A Proteins)+ dendritic cells are responsible for eliciting gut (show GUSB Proteins) intraepithelial lymphocyte response against Encephalitozoon cuniculi.

  4. An important role for CD103 in the control of airway inflammation in asthma.

  5. Donor colonic CD103+ dendritic cells determine the severity of acute graft-versus-host disease.

  6. CXCR3 (show CXCR3 Proteins)-dependent recruitment of cells to inflamed areas was critical for development of the CD8 (show CD8A Proteins)-positive, CD103-negative T lymphocyte population and pathogen clearance.

  7. CD11c (show ITGAX Proteins)(+) CD103(+) cells of Mycobacterium tuberculosis-infected C57BL/6 but not of BALB/c mice induce a high frequency of interferon-gamma (show IFNG Proteins)- or interleukin-17 (show IL17A Proteins)-producing CD4 (show CD4 Proteins)(+) cells.

  8. ITGAE(+) cells play a key role in the development of autoimmune diabetes; this is consistent with the hypothesis that ITGAE(+)CD8 (show CD8A Proteins)(+)T effectors initiate the disease process.

  9. IL-2Rbeta (show IL2RB Proteins)-dependent signaling and CD103 functionally cooperate to maintain tolerance in the gut (show GUSB Proteins) mucosa.

  10. IL-12 (show IL12A Proteins) production by Batf3 (show BATF3 Proteins)-dependent CD103+ dendritic cells is crucial for maintenance of local Th1 (show HAND1 Proteins) immunity against L. major infection.

Human Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE) interaction partners

  1. detected CD103 tumor cells in 41% (16/39) of lymph node-involved adult T-cell leukemia/lymphoma

  2. Levels of GZMA (show GZMA Proteins) and ITGAE mRNAs in colon tissues can identify patients with UC who are most likely to benefit from etrolizumab; expression levels decrease with etrolizumab administration in biomarker(high) patients.

  3. PD-1 (show PDCD1 Proteins)(+)CD103(+) CD8 (show CD8A Proteins) TIL (show TLR1 Proteins) might regain functional antitumor activity, an effect that potentially could be augmented by immune modulation.

  4. This report highlights the diagnostic difficulties and the need of consensus in categorizing clonal CD103(+) lymphocytosis in patients with refractory celiac disease.

  5. Cell-sorting experiments demonstrated that IDO1 (show IDO1 Proteins) expression is found in a subset of CD1a (show CD1A Proteins)(+)CD14 (show NDUFA2 Proteins)(-)langerin (show CD207 Proteins)(+) cells, expressing CD103

  6. Report CD103 expression occurs most frequently in gastrointestinal T-cell lymphomas.

  7. Tumor-infiltrating lymphocytes expressing the tissue resident memory marker CD103 are associated with increased survival in high-grade serous ovarian cancer.

  8. Using a human CTL system model based on a CD8 (show CD8A Proteins)(+)/CD103(-) T cell clone specific of a lung tumor-associated Ag, we demonstrated that the transcription factors Smad2 (show SMAD2 Proteins)/3 and NFAT-1 (show NFAT1 Proteins) are two critical regulators of this process.

  9. Memory CD103+ CD8 (show CD8A Proteins) T cells that persist within the brain after an acute infection with vesicular stomatitis virus are bona fide tissue resident memory cells.

  10. Lymphoid tissue (LT)-resident CD8alpha-positive dendritic cells (DCs) and non(LT)-derived CD103-positive DCs express transgenic XCR1 and are characterized by a unique transcriptional fingerprint, irrespective of their tissue of origin.

ITGAE Protein Profile

Protein Summary

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.

Gene names and symbols associated with ITGAE

  • integrin alpha E, epithelial-associated (Itgae)
  • integrin, alpha E (Itgae)
  • integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) (ITGAE)
  • A530055J10 protein
  • alpha-E1 protein
  • alpha-M290 protein
  • aM290 protein
  • CD103 protein
  • HUMINAE protein

Protein level used designations for ITGAE

integrin alpha M290 , integrin alpha-E , integrin alpha E1, epithelial-associated , integrin, alpha E, epithelial-associated , HML-1 antigen , antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide , integrin alpha-IEL , mucosal lymphocyte 1 antigen

GENE ID SPECIES
16407 Mus musculus
83577 Rattus norvegicus
3682 Homo sapiens
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