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Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) Proteins (ITGAX)

ITGAX encodes the integrin alpha X chain protein. Additionally we are shipping Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) Antibodies (509) and Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ITGAX 16411 Q9QXH4
Rat ITGAX ITGAX 64350 Q9QYE7
ITGAX 3687 P20702
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Top Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 69 to 74 Days
$9,050.32
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 69 to 74 Days
$12,906.52
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$686.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

ITGAX Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , ,
, , ,

More Proteins for Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) Interaction Partners

Mouse (Murine) Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) interaction partners

  1. data demonstrate that CD11c(hi) DCs provide a critical and unexpected role to preserve the immune-privileged CNS in lethal neuroinflammation via regulating the differentiation, function, and trafficking of CD11b(+)Ly-6C(hi) monocytes.

  2. The generation of mouse line with Flip deficiency in cells that express cre under the CD11c promoter is reported.

  3. Probucol effectively retarded atherosclerosis at least partly through lipid-lowering and inhibiting immune maturation of CD11c dendritic cells in STZ-induced diabetic LDLR (show LDLR Proteins) mice.

  4. Dual function of PPARgamma (show PPARG Proteins) in CD11c+ cells ensures immune tolerance in the airways.

  5. CD11c-expressing B cells are located at the T cell/B cell border in spleen and are potent antigen-presenting cells.

  6. Our findings suggest that increased numbers of CD11c(+) macrophages and elevated levels of TNF-alpha (show TNF Proteins) and MMP-3 (show MMP3 Proteins) in AT and ST may explain the relationship between hyperlipidaemia and OA.

  7. Selective ablation of ICOSL (show ICOSLG Proteins) in CD11c+ cells, but not in B cells, dramatically ameliorates kidney and lung inflammation in lupus-prone transgenic mice.

  8. CD11c(+) CD103 (show ITGAE Proteins)(+) cells of Mycobacterium tuberculosis-infected C57BL/6 but not of BALB/c mice induce a high frequency of interferon-gamma (show IFNG Proteins)- or interleukin-17 (show IL17A Proteins)-producing CD4 (show CD4 Proteins)(+) cells.

  9. these findings reveal a role for CSF-1 (show CSF1 Proteins) in mediating the IL-3 (show Il3 Proteins) hematopoietic pathway through monopoiesis, which regulates expansion of CD11c+ macrophages.

  10. the role of the aryl hydrocarbon receptor (show AHR Proteins) in the function of CD11c cells during respiratory viral infection.

Human Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) interaction partners

  1. High expression of CD11c decreased the risk of death and relapse, and may be regarded as an alternative indicator of favorable prognosis in patients with gastric cancer.

  2. the CD11c molecule possesses four different cellular patterns in the periprosthetic tissues.

  3. Data show that secreted aspartic protease 2 (Sap2) of Candida albicans inactivates human macrophage complement factor H (factor H (show CFH Proteins)), factor H (show CFH Proteins)-receptors CD11b/CD18 (show ITGAM Proteins) and CD11c/CD18 (show ITGB2 Proteins).

  4. Data show that the percentage of CD11c positive antigen presenting cells (CD11c(+) APCs (show APCS Proteins)) in the peripheral blood of active pulmonary tuberculosis (APT) patients was much higher than that in the controls.

  5. Data suggest that blood neutrophils expressing CD11c antigen and EMR2 protein be considered as potential biomarkers for sepsis and systemic inflammatory response syndrome (SIRS), respectively.

  6. Modification of Levels of Adhesion Molecule (show NCAM1 Proteins) Expression of Human Innate Immune Cells by Glycopolymers of Marine Bacteria

  7. three of these five genes (CXCL14 (show CXCL14 Proteins), ITGAX, and LPCAT2 (show LPCAT2 Proteins)) harbored polymorphisms associated with aggressive disease development in a human GWAS cohort consisting of 1,172 prostate cancer patients.

  8. infiltration of MBP (show MBL2 Proteins)(+) and CD11c(+) innate immune cells show a significant association with phenotype and disease extent of non-asthmatic chronic rhinosinusitis

  9. CD11a (show ITGAL Proteins), CD11c, and CD18 (show ITGB2 Proteins) gene polymorphisms and susceptibility to Behcet's disease in Koreans.

  10. LFA-1 (show ITGAL Proteins) and CR4 alpha chain (show FCGRT Proteins) phosphorylation is needed for chemokine (show CCL1 Proteins)-induced cross-talk to VLA-4

Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) Protein Profile

Protein Summary

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.

Gene names and symbols associated with ITGAX

  • integrin alpha X (Itgax)
  • integrin, alpha D (Itgad)
  • integrin, alpha X (Itgax)
  • integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX)
  • AI449405 protein
  • CD11C protein
  • Cr4 protein
  • Itgax protein
  • N418 protein
  • RGD1561123 protein
  • SLEB6 protein

Protein level used designations for ITGAX

CD11 antigen-like family member C , CD11C (p150) alpha polypeptide , complement receptor 4 , integrin aX , integrin alpha-X , leukocyte adhesion glycoprotein p150,95 alpha chain , leukocyte adhesion receptor p150,95 , integrin alpha X (Cd11c) , integrin alpha-D , integrin, alpha X (antigen CD11C (p150), alpha polypeptide) , leu M5, alpha subunit , leukocyte surface antigen p150,95, alpha subunit , myeloid membrane antigen, alpha subunit , p150 95 integrin alpha chain

GENE ID SPECIES
16411 Mus musculus
64350 Rattus norvegicus
499271 Rattus norvegicus
3687 Homo sapiens
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