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ITGA11 encodes an alpha integrin. Additionally we are shipping Integrin alpha 11 Antibodies (38) and Integrin alpha 11 Kits (5) and many more products for this protein.
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In NSCLC xenografts in Itga11-knockout mice, collagen cross-linking is associated with stromal alpha11 expression. Loss of tumor stromal alpha11 expression was correlated with decreased collagen reorganization and stiffness.
miR (show MLXIP Proteins)-126a-3p may play a major role in embryo implantation by regulating Itga11, possibly through impairing cell migratory and invasive capacity.
Circulating IGF-1 (show IGF1 Proteins) levels in the sera of mice lacking either alpha2beta1 or alpha11beta1 or both integrins were sharply reduced.
The in vivo indu (show IFNA Proteins)ction of ITGA-11 protein is detected in spleen and lungs of type I IFN-treated BALB/c mice.
analysis of a prokaryotic Scl1 collagen sequence motif that mediates binding to human collagen receptors, integrins alpha2beta1 and alpha11beta1
glycated collagen in the cardiac interstitium triggers an autocrine TGF-beta2 (show TGFB2 Proteins) signaling pathway that stimulates alpha11 integrin expression through Smad2 (show SMAD2 Proteins)/3 binding elements in the alpha11 integrin promoter
Myometrium and uterine fibroids express ITGA11.
Interactions between alpha11 integrins and the Smad (show SMAD1 Proteins)-dependent TGF-beta2 (show TGFB2 Proteins) signalling may contribute to the formation of pro-fibrotic myofibroblasts and the development of a fibrotic interstitium in diabetic cardiomyopathy.
The disturbance of alpha11beta1 mediated interactions to collagen I results in a tremendous reduction of hMSC numbers owing to mitochondrial leakage accompanied by Bcl-2 (show BCL2 Proteins)-associated X protein upregulation.
A new interferon (show IFNA Proteins) stimulated gene. (Integrin alpha 11)
Through interaction between matrix collagen and stromal fibroblasts, integrin alpha 11 stimulates cancer cell growth.
is a major collagen receptor (show ITGA2 Proteins) on human periodontal ligament cells [and plays] a role in collagen lattice remodeling [ITGA11B1]
This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined.
, integrin alpha-11