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Integrin alpha V Proteins (ITGAV)

ITAGV encodes integrin alpha chain V. Additionally we are shipping CD51 Antibodies (250) and CD51 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ITGAV 16410 P43406
ITGAV 3685 P06756
Rat ITGAV ITGAV 296456  
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Top CD51 Proteins at antibodies-online.com

Showing 7 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
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HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
$491.43
Details
HOST_HEK-293 Cells Human His tag   100 μg Log in to see 2 to 3 Days
$451.00
Details

ITGAV Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , , ,
, ,

Top referenced CD51 Proteins

  1. Human CD51 Protein expressed in Wheat germ - ABIN1308183 : Ahn, Mohamedali, Anand, Cheruku, Birch, Sowmya, Cantor, Ranganathan, Inglis, Frank, Agrez, Nice, Baker: Characterization of the interaction between heterodimeric ?v?6 integrin and urokinase plasminogen activator receptor (uPAR) using functional proteomics. in Journal of proteome research 2014 (PubMed)

More Proteins for Integrin alpha V (ITGAV) Interaction Partners

Mouse (Murine) Integrin alpha V (ITGAV) interaction partners

  1. Integrins alphavbeta6 and alphavbeta8 were expressed in non-overlapping patterns by keratinocytes and maintained the epidermal residence of Langerhans cells and tissue resident memory T cells by activating latent TGF-beta (show TGFB1 Proteins).

  2. This work identifies a previously unrecognized role for alphav and the autophagy components LC3 and atg5 in regulating TLR signalling and B-cell immunity.

  3. These data support the hypothesis that IL-1beta (show IL1B Proteins) was initially induced by hyperoxia; alphavbeta6 subsequently interacted with and activated TGF-beta1 (show TGFB1 Proteins).

  4. Gdf-5 (show GDF5 Proteins) induced the expression of the alpha5 sub-unit, while Bmp-7 (show BMP7 Proteins) induced the expression of the alphaV sub-unit.

  5. These results suggest that phloretin was an inhibitor of actin podosomes and sealing zone, disrupting alpha5beta3 integrin-c-Src-Pyk2/Syk signaling pathway for the regulation of actin cytoskeletal organization in osteoclasts.

  6. TN-C (show TNC Proteins) may enhance inflammatory responses by accelerating macrophage migration and synthesis of proinflammatory/profibrotic cytokines via integrin alphaVbeta3/FAK (show PTK2 Proteins)-Src (show SRC Proteins)/NF-kappaB (show NFKB1 Proteins), resulting in increased fibrosis.

  7. Lung histology revealed aberrant elastin (show ELN Proteins) production and impaired lung septation in oxygen-exposed lungs, while tropoelastin (show ELN Proteins), integrin alphav, fibulin-1 (show FBLN1 Proteins), fibulin-2 (show FBLN2 Proteins) and fibulin-4 (show FBLN4 Proteins) gene expression were elevated.

  8. Knock-in mice expressing a CCN1 (show CCNA2 Proteins) mutant that is unable to bind alphavbeta5/alphavbeta3 were impaired in ductular reaction. CCN1 (show CCNA2 Proteins), acting through its alphav beta3/alphav beta5 binding site, is critical for survival after bile duct ligation.

  9. These results suggest that integrin alphavbeta3 mediates the synergetic regulation of Cbfa1 (show RUNX2 Proteins) transcription activity by gravity and IGF-1 (show IGF1 Proteins) via PI3K signaling.

  10. Angptl3 (show ANGPTL3 Proteins) could induce actin filament rearrangement, mainly in lamellipodia formation, and that this process was mediated by integrin alpha(V)beta-mediated FAK (show PTK2 Proteins) and PI3K phosphorylation and Rac1 activation.[ITGAV]

Human Integrin alpha V (ITGAV) interaction partners

  1. ERK (show EPHB2 Proteins)-mediated transcription regulation of the alphav monomer is regulated by T3. Thyroid hormones are potent alphavbeta3-ligands, driving ovarian cancer cell proliferation.

  2. Integrins alphavbeta6 and alphavbeta8 were expressed in non-overlapping patterns by keratinocytes and maintained the epidermal residence of Langerhans cells and tissue resident memory T cells by activating latent TGF-beta (show TGFB1 Proteins).

  3. The driving role of the tumour microenvironment on CRC (show CALR Proteins) dissemination, here detected, and described, strengthens and adds new value to the concept that a5b1 integrin can be an appropriate and relevant therapeutic target for the control of CRC (show CALR Proteins) metastases.

  4. These findings suggest that enhanced integrin alphavbeta3 expression in addition to enhanced FGFR1 (show FGFR1 Proteins) expression is critical for FGF1 (show FGF1 Proteins) to augment TGF-beta1 (show TGFB1 Proteins)-induced EMT (show ITK Proteins) in mammary epithelial cells.

  5. The combined impacts of alphav-integrin and HER2 (show ERBB2 Proteins) influence the invasive phenotype of breast cancer cells.

  6. alpha5beta1 and alphavbeta3 each mediate actin cytoskeletal remodeling in response to stiffening or cyclic stretching of the extracellular matrix.

  7. Either mutation of two amino acids (D205A,D207A), or deletion of seven amino acids (Del202-208) of the Borrelia burgdorferi P66 (show POLD3 Proteins) protein significantly reduced binding ability to integrin alphavbeta3.

  8. Integrin alphavbeta3 is required for cathepsin B (show CTSB Proteins)-induced hepatocellular carcinoma progression

  9. These results suggest that melatonin exerts anti-migratory and anti-invasive effects on glioma cells in response to hypoxia via reactive oxygen species-alphavbeta3 integrin-FAK (show PTK2 Proteins)/Pyk2 (show PTK2B Proteins) signaling pathways.

  10. Osteopontin (show SPP1 Proteins) might promote a cancer stem cell-like phenotype via the alphavbeta3-NF-kappaB (show NFKB1 Proteins)-HIF-1alpha (show HIF1A Proteins) pathway in hepatocellular carcinoma.

Pig (Porcine) Integrin alpha V (ITGAV) interaction partners

  1. The observed effects of shear stress on integrin alpha(v)beta(3) and p38 MAPK (show MAPK14 Proteins) activation, as well as on FGF-2 (show FGF2 Proteins) release could be mimicked by application of pancreatic elastase to static endothelial cells.

  2. Inhibition of integrin alphavbeta3 prevents urokinase plasminogen (show PLG Proteins) activator-mediated impairment of cerebrovasodilation after cerebral hypoxia/ischemia.

Cow (Bovine) Integrin alpha V (ITGAV) interaction partners

  1. Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.

  2. specific substitutions show that the stable binding between foot-and-mouth disease virus VP1 and integrin alphavbeta6 is dependent on a helical structure and, specifically, two leucine residues at positions +1 and RGD +4 from the RGD motif.

  3. These results demonstrate the critical role of the RhoA (show RHOA Proteins)/alphavbeta5 integrin pathway in mediating Pseudomonas aeruginosa-induced lung vascular permeability.

CD51 (ITGAV) Protein Profile

Protein Summary

ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8\; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands\; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with Integrin alpha V Proteins (ITGAV)

  • integrin, alpha V (ITGAV)
  • integrin alpha V (Itgav)
  • integrin, alpha V (Itgav)
  • integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) (ITGAV)
  • 1110004F14Rik protein
  • 2610028E01Rik protein
  • Cd51 protein
  • D430040G12Rik protein
  • MSK8 protein
  • VNRA protein
  • VTNR protein

Protein level used designations for Integrin alpha V Proteins (ITGAV)

integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) , alphav integrin , integrin alpha V , integrin alpha-V , vitronectin receptor alpha polypeptide (VNRA) , vitronectin receptor subunit alpha , antigen identified by monoclonal antibody L230 , integrin alphaVbeta3 , Dnmt3l-ps1 pseudogene , alphaV integrin , integrin alpha v , vitronectin receptor alpha subunit , integrin alpha V subunit

GENE ID SPECIES
100068706 Equus caballus
443143 Ovis aries
16410 Mus musculus
3685 Homo sapiens
296456 Rattus norvegicus
488437 Canis lupus familiaris
397285 Sus scrofa
396420 Gallus gallus
281875 Bos taurus
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