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Integrin beta 1 Proteins (ITGB1)

Integrins are heterodimeric proteins made up of alpha and beta subunits. Additionally we are shipping Integrin beta 1 Antibodies (839) and Integrin beta 1 Kits (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ITGB1 16412 P09055
ITGB1 24511 P49134
ITGB1 3688 P05556
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Top Integrin beta 1 Proteins at

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
Yeast Rat His tag Integrin beta 1 (ITGB1) (AA 21-729) protein (His tag) expressed in E. coli 1 mg Log in to see 56 to 66 Days
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
HOST_Human Cells Human His tag 50 μg Log in to see 16 Days
HOST_Escherichia coli (E. coli) Human GST tag   1 mg Log in to see 3 to 4 Days
Yeast Sheep His tag   1 mg Log in to see 56 to 66 Days

ITGB1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
, ,
Rat (Rattus)

Human , , , ,
, , ,

Top referenced Integrin beta 1 Proteins

  1. Human ITGB1 Protein expressed in Wheat germ - ABIN2752830 : Ahn, Mohamedali, Anand, Cheruku, Birch, Sowmya, Cantor, Ranganathan, Inglis, Frank, Agrez, Nice, Baker: Characterization of the interaction between heterodimeric ?v?6 integrin and urokinase plasminogen activator receptor (uPAR) using functional proteomics. in Journal of proteome research 2014 (PubMed)

More Proteins for Integrin beta 1 (ITGB1) Interaction Partners

Xenopus laevis Integrin beta 1 (ITGB1) interaction partners

  1. Findings demonstrate the neurotrophin (show BDNF Proteins), BDNF (show BDNF Proteins)-dependent formation of integrin beta1-based adhesions in the growth cone and reveal how a positive regulator of substrate adhesions can block the negative remodeling and growth inhibitory effects of myelin-associated glycoprotein (show MAG Proteins) .

  2. Findings identify beta(1)-integrin as an important functional cargo during Ca(2+)-dependent rapid endocytosis stimulated by a diffusible guidance cue in Xenopus spinal neurons.

Mouse (Murine) Integrin beta 1 (ITGB1) interaction partners

  1. These findings show that talin and kindlin cooperatively activate integrins leading to fibronectin (show FN1 Proteins) binding and adhesion.

  2. These results suggest that Tie2 (show TEK Proteins) signaling induces alpha4beta1 integrin activation on bone marrow-mast cell progenitor for adhesion to VCAM-1 (show VCAM1 Proteins).

  3. LRP1 (show LRP1 Proteins) interacts with beta1-integrin mediating integrin internalization and thus correlates with downstream signaling of beta1-integrin such as focal adhesion dynamics

  4. 4.1G has a role in cell adhesion, spreading, and migration in MEF cells by modulating the surface expression of beta1 integrin and subsequent downstream signal transduction

  5. DPP-4 (show DPP4 Proteins) and integrin beta1 interactions regulate key endothelial cell signal transduction in both physiological and pathological conditions including endothelial mesenchymal transformation.

  6. RECK (show RECK Proteins)-mediated beta1-Integrin regulation by TGF-beta1 (show TGFB1 Proteins) is critical for wound contraction in mice.

  7. The findings of this study showed that astrocytic beta1-itg (show SLC11A1 Proteins) has an important role in defining cellular properties of the blood brain barrier in the cerebral cortex.

  8. the epithelial interaction between fibronectin (show FN1 Proteins) and beta1 integrin is important for ameloblast differentiation and enamel formation.

  9. interaction of alpha6beta1 in embryonic stem cells (ECCs) with laminin-1 (show LAMA1 Proteins) activates alpha6beta1/CD151 (show CD151 Proteins) signaling which programs ESCs (show NR2E3 Proteins) toward the endothelial cells lineage fate

  10. Data show that active active focal adhesion kinase (FAK) localizes to integrin-containing endosomes.

Human Integrin beta 1 (ITGB1) interaction partners

  1. study demonstrates the pivotal role of the extracellular protein, fibulin-5 (show FBLN5 Proteins), on the adhesion and proliferation of human keloid-derived cells, through binding to integrin beta-1

  2. Twist-ITGB1-FAK (show PTK2 Proteins)/ILK (show ILK Proteins) pathway and their downstream signaling network dictate the Twist-induced EMT (show ITK Proteins) process in human mammary epithelial cells and breast cancer cells

  3. These results indicate that the effects of GMFG on monocyte migration and adhesion probably occur through preventing ubiquitin-mediated proteasome degradation of alpha5beta1-integrin and facilitating effective beta1-integrin recycling back to the plasma membrane.

  4. Insulin (show INS Proteins)-like growth factor-independent insulin-like growth factor binding protein 3 (show IGFBP3 Proteins) promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells via integrin beta1 signaling.

  5. the role of the CD151 (show CD151 Proteins)-alpha3beta1 complex in carcinoma progression is context dependent, and may depend on the mode of tumor cell invasion.

  6. GM2 (show CYB5D2 Proteins) mediats tumor cell migration by interacting with ITGB1 leading to downstream signaling and the phosphorylation of ERK (show EPHB2 Proteins) MAP kinases.

  7. G-CSF (show CSF3 Proteins) stimulates beta1 integrin expression and Swan (show RBM12 Proteins) 71 cell migration by activating PI3K (show PIK3CA Proteins) and MAPK (show MAPK1 Proteins) signaling pathways.

  8. IGFBP-2 enhances endothelial progenitor cell adhesion to HUVECs via Integrin alpha5beta1. The RGD motif in the IGFBP-2 C-domain is required for interaction with integrin alpha5beta1.

  9. Human uPAR (show PLAUR Proteins) activation and its association with beta1-integrin are required for PDGF (show PDGFA Proteins)-AB-induced migration.

  10. Data show that CD151 (show CD151 Proteins) protein (CD151 (show CD151 Proteins))-alpha3beta1 integrin complexes cooperated with epidermal growth factor receptor (EGFR (show EGFR Proteins)) to drive tumor cell motility.

Pig (Porcine) Integrin beta 1 (ITGB1) interaction partners

  1. beta1-integrin antigen-antibody interactions and the distribution of beta1-integrin protein on spermatogonial stem cell membrane were demonstrated using atomic force microscopy

Cow (Bovine) Integrin beta 1 (ITGB1) interaction partners

  1. The overall findings suggest that the secreted galectin-3 (show LGALS3 Proteins) stimulated by PGF (show PGF Proteins) plays a role in structural luteolysis by binding to beta 1 integrin.

  2. Putative function of fibronectin (show FN1 Proteins) and its receptor (integrin alpha(5 (show ITGA5 Proteins))beta(1)) in male and female gametes during bovine fertilization in vitro.

  3. integrin activation with shear stress results in SFK-regulated caveolin-1 phosphorylation that, in turn, mediates Csk association at integrin sites, where it plays a role in downstream, shear-stimulated myosin light chain diphosphorylation.

  4. Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.

  5. both the gpIb-VWF (show VWF Proteins) interaction and the integrin alpha(2 (show ITGA2 Proteins))beta(1)-collagen interaction contribute to platelet adhesion under high shear stress; integrin alpha(II (show GSTA3 Proteins))beta(1) makes a greater contribution to adhesion to type I collagen because less VWF (show VWF Proteins) is bound

  6. TRPV4 (show TRPV4 Proteins) channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling.

Integrin beta 1 (ITGB1) Protein Profile

Protein Summary

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

Gene names and symbols associated with Integrin beta 1 Proteins (ITGB1)

  • integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) (itgb1-b)
  • integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) (ITGB1)
  • integrin beta 1 (fibronectin receptor beta) (Itgb1)
  • integrin, beta 1 (Itgb1)
  • 4633401G24Rik protein
  • AA409975 protein
  • AA960159 protein
  • CD29 protein
  • ENSMUSG00000051907 protein
  • FNRB protein
  • Gm9863 protein
  • GPIIA protein
  • itgb1 protein
  • MDF2 protein
  • MSK12 protein
  • VLA-BETA protein
  • VLAB protein

Protein level used designations for Integrin beta 1 Proteins (ITGB1)

integrin beta 1 , integrin beta-1* , integrin beta-1-B , VLA-4 subunit beta , fibronectin receptor subunit beta , integrin beta-1 , beta OL , beta oligodendroglia , integrin VLA-4 subunit beta , integrin beta 1 (fibronectin receptor beta) , glycoprotein IIa , integrin VLA-4 beta subunit , very late activation protein, beta polypeptide , integrin beta-1 subunit , CSAT antigen , JG22 antigen , RGD-receptor , Fibronectin receptor subunit beta , Integrin VLA-4 subunit beta , Integrin subunit beta-1

399443 Xenopus laevis
574312 Macaca mulatta
100055024 Equus caballus
16412 Mus musculus
24511 Rattus norvegicus
3688 Homo sapiens
397019 Sus scrofa
751821 Felis catus
374058 Gallus gallus
477956 Canis lupus familiaris
281876 Bos taurus
443141 Ovis aries
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