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Integrins are heterodimeric proteins made up of alpha and beta subunits. Additionally we are shipping Integrin beta 1 Kits (25) and Integrin beta 1 Proteins (19) and many more products for this protein.
Showing 10 out of 846 products:
Human Monoclonal ITGB1 Primary Antibody for IHC (p) - ABIN180522
Friedlander, Zagzag, Shiff, Cohen, Allen, Kelly, Grumet: Migration of brain tumor cells on extracellular matrix proteins in vitro correlates with tumor type and grade and involves alphaV and beta1 integrins. in Cancer research 1996
Show all 2 references for ABIN180522
Human Monoclonal ITGB1 Primary Antibody for FACS - ABIN1106237
Erle, Briskin, Butcher, Garcia-Pardo, Lazarovits, Tidswell: Expression and function of the MAdCAM-1 receptor, integrin alpha 4 beta 7, on human leukocytes. in Journal of immunology (Baltimore, Md. : 1950) 1994
Show all 2 references for ABIN1106237
Dog (Canine) Monoclonal ITGB1 Primary Antibody for FACS, IP - ABIN259706
Símová, Klíma, Cermak, Sourková, Andera: Arf and Rho GAP adapter protein ARAP1 participates in the mobilization of TRAIL-R1/DR4 to the plasma membrane. in Apoptosis : an international journal on programmed cell death 2008
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Human Monoclonal ITGB1 Primary Antibody for FACS, IHC (fro) - ABIN119208
Marshall, Rutherford, Happerfield, Hanby, McCartney, Newton-Bishop, Hart: Comparative analysis of integrins in vitro and in vivo in uveal and cutaneous melanomas. in British journal of cancer 1998
Show all 2 references for ABIN119208
Human Monoclonal ITGB1 Primary Antibody for FACS, IHC (fro) - ABIN119209
Pillay, Ramakers, Kamp, Loi, Lam, Hietbrink, Leenen, Tool, Pickkers, Koenderman: Functional heterogeneity and differential priming of circulating neutrophils in human experimental endotoxemia. in Journal of leukocyte biology 2010
Show all 2 references for ABIN119209
Human Monoclonal ITGB1 Primary Antibody for EIA, FACS - ABIN119428
Mould, Garratt, Askari, Akiyama, Humphries: Identification of a novel anti-integrin monoclonal antibody that recognises a ligand-induced binding site epitope on the beta 1 subunit. in FEBS letters 1995
Show all 2 references for ABIN119428
Mouse (Murine) Monoclonal ITGB1 Primary Antibody for Func, FACS - ABIN120158
Noto, Kato, Okumura, Yagita: Identification and functional characterization of mouse CD29 with a mAb. in International immunology 1995
Human Monoclonal ITGB1 Primary Antibody for FACS - ABIN1106238
Lee, Huang, Chiang, Chiou, Chen, Hsieh, Jiang: Multipotential mesenchymal stem cells from femoral bone marrow near the site of osteonecrosis. in Stem cells (Dayton, Ohio) 2003
Findings demonstrate the neurotrophin (show BDNF Antibodies), BDNF (show BDNF Antibodies)-dependent formation of integrin beta1-based adhesions in the growth cone and reveal how a positive regulator of substrate adhesions can block the negative remodeling and growth inhibitory effects of myelin-associated glycoprotein (show MAG Antibodies) .
Findings identify beta(1)-integrin as an important functional cargo during Ca(2+)-dependent rapid endocytosis stimulated by a diffusible guidance cue in Xenopus spinal neurons.
low expression of alpha2beta1 integrin increased protein kinase B (AKT (show AKT1 Antibodies)) activation and alpha-smooth muscle actin (show ACTG2 Antibodies) (alpha-SMA (show SMN1 Antibodies)) expression. This occurred due to the instability of phosphatase and tensin homolog (PTEN (show PTEN Antibodies)) in myofibroblasts on fibrillar collagen.
By modulating its affinity with kindlin, beta3 integrin (show ITGB3 Antibodies) may be able to locate near the cell edge where it can control beta1 integrin activation and clustering.
These findings indicated that mechanical strain promoted osteoblastic differentiation through integrinbeta1mediated beta-catenin (show CTNNB1 Antibodies) signaling.
TERT (show TERT Antibodies) may promote gastric cancer metastasis through the TERT (show TERT Antibodies)-miR (show MLXIP Antibodies)-29a-ITGB1 regulatory pathway.
the rate of collagen I degradation was increased in Poldip2 (show POLDIP2 Antibodies)(+/-) vs. Poldip2 (show POLDIP2 Antibodies)(+/+) MASMs. Conversely, activation of the PI3K/Akt (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) signaling pathway, involved in regulation of protein synthesis, was significantly elevated in Poldip2 (show POLDIP2 Antibodies)(+/-) MASMs as was beta1-integrin expression.
These findings show that talin and kindlin cooperatively activate integrins leading to fibronectin (show FN1 Antibodies) binding and adhesion.
These results suggest that Tie2 (show TEK Antibodies) signaling induces alpha4beta1 integrin activation on bone marrow-mast cell progenitor for adhesion to VCAM-1 (show VCAM1 Antibodies).
LRP1 (show LRP1 Antibodies) interacts with beta1-integrin mediating integrin internalization and thus correlates with downstream signaling of beta1-integrin such as focal adhesion dynamics
4.1G has a role in cell adhesion, spreading, and migration in MEF cells by modulating the surface expression of beta1 integrin and subsequent downstream signal transduction
DPP-4 (show DPP4 Antibodies) and integrin beta1 interactions regulate key endothelial cell signal transduction in both physiological and pathological conditions including endothelial mesenchymal transformation.
Expression levels of CD98 (show SLC3A2 Antibodies) and beta1-integrin-A (the activated form of beta1-integrin) were significantly increased in hepatocellular carcinoma (HCC (show FAM126A Antibodies)) tissues relative to those of normal liver tissues.
High expression of ITGB1 is associated with migration and invasion of nonsmall cell lung cancer.
Our results suggest that an impairment in adhesion exists in vitiligo (show MITF Antibodies) skin, which is supported by the diminished immunohistochemical expression of laminin, beta1 integrin, ICAM-1 (show ICAM1 Antibodies) and VCAM-1 (show VCAM1 Antibodies).
The altered expression of anti-apoptotic gene Bcl-2 (show BCL2 Antibodies) played critical roles in regulating both spontaneous and radiation-induced apoptosis in the presence of RelB (show RELB Antibodies) knockdown. For the first time, we showed that RelB (show RELB Antibodies) knockdown significantly attenuated the migration and invasion of DU145 prostate cancer cells, due to the reduction of integrin b-1
ITGB1 role in hepatocellular carcinoma cell adhesion and motility
Data show that high mobility group nucleosomal binding domain 2 (HMGN2 (show HMGN2 Antibodies)) knockdown induced the increased expression of alpha5beta1 integrin on cell membranes, which resulted in a significant increase in Klebsiella pneumoniae internalization.
ectopic expression of miR-17 in ovarian cancer cells resulted in repressed ILK (show ILK Antibodies) phosphorylation as well as decreased production of active matrix metalloproteinase-2 (MMP-2 (show MMP2 Antibodies)). Our results indicated that miR-17 hampered ovarian cancer peritoneal propagation by targeting integrin a5 and b1.
results provide insight into the regulation of beta1 integrin through miR (show MLXIP Antibodies)-199a-5p-mediated Ets-1 (show ETS1 Antibodies) silence and will help in designing new therapeutic strategies to inhibit signal pathways induced by miR (show MLXIP Antibodies)-199a-5p in breast cancer invasion
ITGB1 expression selected exclusively by integrative topological measures correlated with clinical stages and prognosis, which was further validated with two independent cohorts of esophageal squamous cell carcinoma samples
Nodule number and HIF-1alpha (show HIF1A Antibodies) and ITGbeta1 protein expression levels were all positively correlated with gastric cancer progression.
beta1-integrin antigen-antibody interactions and the distribution of beta1-integrin protein on spermatogonial stem cell membrane were demonstrated using atomic force microscopy
The overall findings suggest that the secreted galectin-3 (show LGALS3 Antibodies) stimulated by PGF (show PGF Antibodies) plays a role in structural luteolysis by binding to beta 1 integrin.
Putative function of fibronectin (show FN1 Antibodies) and its receptor (integrin alpha(5 (show ITGA5 Antibodies))beta(1)) in male and female gametes during bovine fertilization in vitro.
integrin activation with shear stress results in SFK-regulated caveolin-1 phosphorylation that, in turn, mediates Csk association at integrin sites, where it plays a role in downstream, shear-stimulated myosin light chain diphosphorylation.
Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.
both the gpIb-VWF (show VWF Antibodies) interaction and the integrin alpha(2 (show ITGA2 Antibodies))beta(1)-collagen interaction contribute to platelet adhesion under high shear stress; integrin alpha(II (show GSTA3 Antibodies))beta(1) makes a greater contribution to adhesion to type I collagen because less VWF (show VWF Antibodies) is bound
TRPV4 (show TRPV4 Antibodies) channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling.
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
integrin beta 1
, integrin beta-1*
, integrin beta-1-B
, VLA-4 subunit beta
, fibronectin receptor subunit beta
, integrin beta-1
, beta OL
, beta oligodendroglia
, integrin VLA-4 subunit beta
, integrin beta 1 (fibronectin receptor beta)
, glycoprotein IIa
, integrin VLA-4 beta subunit
, very late activation protein, beta polypeptide
, integrin beta-1 subunit
, CSAT antigen
, JG22 antigen
, Fibronectin receptor subunit beta
, Integrin VLA-4 subunit beta
, Integrin subunit beta-1