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Integrin beta 3 Proteins (ITGB3)

The ITGB3 protein product is the integrin beta chain beta 3. Additionally we are shipping Integrin beta 3 Antibodies (641) and Integrin beta 3 Kits (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ITGB3 16416 O54890
Rat ITGB3 ITGB3 29302  
ITGB3 3690 P05106
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Top Integrin beta 3 Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 11 to 13 Days
$563.20
Details
HOST_Escherichia coli (E. coli) Mouse His tag,S tag 100 μg Log in to see 11 to 13 Days
$668.80
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$747.45
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ITGB3 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
, ,
Human , ,
,

More Proteins for Integrin beta 3 (ITGB3) Interaction Partners

Mouse (Murine) Integrin beta 3 (ITGB3) interaction partners

  1. suppression of beta3-integrin in mice leads to the activation of a neuropilin-1 (NRP1 (show NRP1 Proteins))-dependent cell migration pathway in endothelial cells via a mechanism that depends on NRP1 (show NRP1 Proteins)'s mobilisation away from mature focal adhesions following VEGF (show VEGFA Proteins)-stimulation

  2. Deletion of Itgb3 causes increased B-cell responses to TLR stimulation in vitro.

  3. integrin beta3-mediated signaling in smooth muscle cells links elastin (show ELN Proteins) deficiency and pathological stenosis, and inhibiting this pathway is an attractive therapeutic strategy for supravalvular aortic stenosis.

  4. The clathrin-mediated endocytic machinery combines with Dab2 (show DAB2 Proteins) to facilitate the endocytosis of RGD-integrin-beta3 clusters.

  5. Integrin beta 3 causes arteriovenous graft occlusion.

  6. Taken together, our results reveal that TD-26 is a novel antithrombotic compound exhibiting both integrin alphaIIbbeta3 inhibition and PI3K signaling blockage, with a low bleeding risk.

  7. Conformational activation of talin by PREL-1 (show APBB1IP Proteins) triggers integrin-mediated cell adhesion.

  8. beta3/kindlin-2 (show FERMT2 Proteins) interaction promotes outside-in alphaVbeta3 signaling selectively, with biological consequences in vivo

  9. alphaIIbbeta3 regulates Syk (show SYK Proteins) through an ITAM-independent pathway in mice and provide novel insight into the course of events underlying Syk (show SYK Proteins) activation and hemITAM phosphorylation by CLEC-2 (show CLEC1B Proteins)

  10. Integrin alphav beta3/Dap12 (show TYROBP Proteins) double-deficient developed profound osteoporosis.

Human Integrin beta 3 (ITGB3) interaction partners

  1. This study shows correlation of blood clot stiffness with platelet integrin alpha-IIb beta3 activity, aspirin usage, and transfusion risk in cardiopulmonary bypass patients.

  2. T4, but not T3, controls integrin's outside-in signaling by phosphorylating tyrosine 759 in the beta3 subunit. ERK (show EPHB2 Proteins)-mediated transcription regulation of the b3 monomer is regulated by T3 and T4which are alphavbeta3-ligands driving ovarian cancer cell proliferation .

  3. Our data provide evidence that ADAM23 (show Adam23 Proteins) plays a role in suppression of cancer cell progression through interaction with aVb3 integrin, and suggest that downregulation of ADAM23 (show Adam23 Proteins) in SP cells may contribute toward providing a cancer stem cell phenotype

  4. Data show that immune thrombocytopenia (ITP (show ITPA Proteins)) is an autoimmune bleeding disorder characterized by low platelet count and presence of IgG autoantibodies to platelet surface glycoproteins, such as alpha IIbbeta3 integrins.

  5. Data suggest that the ligand AGDV tetrapeptide binds to ITGB3/GPIIIa subunit and induces complete opening of headpiece of integrin alphaIIb/beta3 complex; AGDV appears to have very little contact with ITGA2B/GPIIb subunit.

  6. CD61-overexpressing human umbilical cord mesenchymal stem cell, which had turned into primordial germ-like cells-like cells, could be further differentiated into male germ-like cells.

  7. The frequencies of the rare alleles of CCR2 (show CCR2 Proteins), ITGB3, and 3'UTR of c-fms (show CSF1R Proteins) in the Old Believers are lower than in the sample of Novosibirsk Russians, and the rare allele of DBH (show DBH Proteins) is more frequent

  8. Data suggest that reduced ability of AnxA6 (show ANXA6 Proteins)-expressing cells to migrate is associated with decreased cell surface expression of integrins alphaVbeta3 and alpha5beta1.

  9. results demonstrate that beta3 integrin expression depends on the source of the fibroblast and that its expression inhibits alphaSMA (show ACTA2 Proteins) expression (and thus the myofibroblast phenotype).

  10. 33Leu --> Pro substitution of GPIIIa does not influence the prevalence and extent of angiographically defined coronary artery disease in general population, although apparently playing a role among younger patients.

Pig (Porcine) Integrin beta 3 (ITGB3) interaction partners

  1. The observed effects of shear stress on integrin alpha(v (show ITGAV Proteins))beta(3) and p38 MAPK (show MAPK14 Proteins) activation, as well as on FGF-2 (show FGF2 Proteins) release could be mimicked by application of pancreatic elastase to static endothelial cells.

  2. structure and distribution of the CD61 provides insight into the physiological function of the porcine beta(3) integrins and should be of importance in understanding the role of this integrin family in biological processes

  3. Inhibition of integrin alphavbeta3 (show ITGAV Proteins) prevents urokinase plasminogen (show PLG Proteins) activator-mediated impairment of cerebrovasodilation after cerebral hypoxia/ischemia.

Cow (Bovine) Integrin beta 3 (ITGB3) interaction partners

  1. alphavbeta3 integrin engagement in vascular endothelium regulates Ca2 (show CA2 Proteins)+-dependent K+ current

  2. Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.

Integrin beta 3 (ITGB3) Protein Profile

Protein Summary

The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

Gene names and symbols associated with Integrin beta 3 Proteins (ITGB3)

  • integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ITGB3)
  • integrin beta 3 (Itgb3)
  • integrin, beta 3 (Itgb3)
  • BDPLT2 protein
  • BDPLT16 protein
  • CD61 protein
  • GP3A protein
  • GPIIIA protein
  • GT protein
  • INGRB3 protein
  • INTB3 protein
  • integrin protein

Protein level used designations for Integrin beta 3 Proteins (ITGB3)

integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) , integrin beta3 , GPIIIa , integrin beta-3 , platelet gpIIIa , platelet membrane glycoprotein IIIa , integrin beta 3 (Cd61) , beta3 integrin , glycoprotein GPIIIa , integrin beta 3 , integrin beta-3 subunit

GENE ID SPECIES
100423047 Ovis aries
16416 Mus musculus
29302 Rattus norvegicus
3690 Homo sapiens
397063 Sus scrofa
282642 Bos taurus
374209 Gallus gallus
403788 Canis lupus familiaris
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