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anti-Integrin-Linked Kinase (ILK) Antibodies

Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Additionally we are shipping Integrin-Linked Kinase Kits (27) and Integrin-Linked Kinase Proteins (25) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ILK 16202 O55222
ILK 3611 Q13418
ILK 170922 Q99J82
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Top anti-Integrin-Linked Kinase Antibodies at antibodies-online.com

Showing 10 out of 227 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of ILK1 expression in 3T3 cell lysate. 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated IHC (p), WB Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ILK Antibody (S246) (ABIN391996), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of anti-ILK Antibody (S246) (ABIN391996) in Hela cell line lysates (35 µg/lane). ILK(arrow) was detected using the purified polyclonal antibody (1:60 dilution). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-ILK1 Pab (ABIN391993) in HL60 cell lysate. ILK1 (Arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-ILK Antibody (T173) (ABIN391997) in NCI-H460 cell line lysates (35 µg/lane). EN1(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with Phospho ILK Antibody (T173) (ABIN391997) antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p) 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain, using ILK (Phospho-Ser246) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated DB Dot blot analysis of anti-Phospho ILK-S343 Pab (ABIN650820) on nitrocellulose membrane.  50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA 0.4 mL Log in to see 6 to 8 Days
$390.50
Details

ILK Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Integrin-Linked Kinase Antibodies

  1. Human Polyclonal ILK Primary Antibody for IHC (p), WB - ABIN391993 : Troussard, Mawji, Ong, Mui, St -Arnaud, Dedhar: Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation. in The Journal of biological chemistry 2003 (PubMed)
    Show all 6 references for ABIN391993

  2. Human Polyclonal ILK Primary Antibody for EIA - ABIN358419 : Li, Yang, Dai, Wu, Liu: Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis. in The Journal of clinical investigation 2003 (PubMed)
    Show all 5 references for ABIN358419

  3. Human Polyclonal ILK Primary Antibody for EIA, IHC (p) - ABIN359885 : Marotta, Parhar, Owen, Dedhar, Salh: Characterisation of integrin-linked kinase signalling in sporadic human colon cancer. in British journal of cancer 2003 (PubMed)
    Show all 5 references for ABIN359885

  4. Human Polyclonal ILK Primary Antibody for EIA, IHC (p) - ABIN359883 : Cordes, van Beuningen: Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3beta (GSK-3beta) in vitro. in British journal of cancer 2003 (PubMed)
    Show all 4 references for ABIN359883

  5. Human Polyclonal ILK Primary Antibody for IHC (p), WB - ABIN391997 : Fukuda, Guo, Shi, Wu: CH-ILKBP regulates cell survival by facilitating the membrane translocation of protein kinase B/Akt. in The Journal of cell biology 2003 (PubMed)
    Show all 4 references for ABIN391997

  6. Human Polyclonal ILK Primary Antibody for IHC, ELISA - ABIN1532048 : Hannigan, Leung-Hagesteijn, Fitz-Gibbon, Coppolino, Radeva, Filmus, Bell, Dedhar: Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase. in Nature 1996 (PubMed)
    Show all 2 references for ABIN1532048

  7. Human Polyclonal ILK Primary Antibody for IHC, WB - ABIN223143 : Hu, Sun, Xie, Huang, Jia, Yao, Ge: Rosuvastatin changes cytokine expressions in ischemic territory and preserves heart function after acute myocardial infarction in rats. in Journal of cardiovascular pharmacology and therapeutics 2013 (PubMed)

  8. Human Polyclonal ILK Primary Antibody for DB - ABIN650820 : Srikanth, Das, Berns, Kim, Stupp, Kessler: Nanofiber-mediated inhibition of focal adhesion kinase sensitizes glioma stemlike cells to epidermal growth factor receptor inhibition. in Neuro-oncology 2013 (PubMed)

More Antibodies against Integrin-Linked Kinase Interaction Partners

Fruit Fly (Drosophila melanogaster) Integrin-Linked Kinase (ILK) interaction partners

  1. Targeted knockdown of the integrin focal adhesion complex components beta-integrin, PINCH (show LIMS1 Antibodies), and integrin-linked kinase caused formation of multinucleate epidermal cells within the Drosophila larval epidermis.

  2. PINCH (show LIMS1 Antibodies) and ILK have an independent capacity to localize at muscle attachment sites in vivo.

  3. ILK functions as an essential hub in the assembly of its partner proteins at sites of integrin adhesion.

Xenopus laevis Integrin-Linked Kinase (ILK) interaction partners

Mouse (Murine) Integrin-Linked Kinase (ILK) interaction partners

  1. Work provides a new tool for studying mouse oligodendrocyte precursor cell migration and highlights the role of integrin-linked kinase in its regulation on extracellular matrix proteins relevant to multiple sclerosis.

  2. We conclude that ILK negatively and independently of PI3K regulated MEF2C (show MEF2C Antibodies) phosphorylation activity and MCK (show CKM Antibodies) mRNA expression in C2C12 cells

  3. high extracellular concentration of phosphate induced senescence in cultured smooth muscle through the activation of IGF-1 (show IGF1 Antibodies) receptor and ILK overexpression

  4. This study demonstrates a role for ILK in regulating laminin2-mediated adhesion and Ln-2-independent growth cone size/activity in oligodendrocyte

  5. ILK is indispensable for Brain-derived neurotrophic factor-mediated hippocampal neurogenesis and memory enhancement upon Environment enrichment stimuli via regulating glycogen synthase kinase-3beta activity.

  6. ELMO2 (show ELMO2 Antibodies)-RhoG-ILK complex has a key role in integrin-independent stabilization of the microtubule network in differentiated keratinocytes.

  7. ILK is a key regulator of the bulge extracellular matrix microenvironment, thereby governing the activation and maintenance of hair follicle stem cells.

  8. CTGF (show CTGF Antibodies) overexpression induces epithelial to mesenchymal transition in mouse primary AT II cells, which is mediated by ILK

  9. These data demonstrate that ILK is a linker between Integrin receptors and the Dynactin (show DCTN1 Antibodies) complex to regulate mitotic spindle orientation.

  10. These observations demonstrate an important role for beta1-integrin/ILK signaling in regulating astrogliosis from ESCs (show NR2E3 Antibodies) and suggest ILK as a potential target for limiting glial scar formation after nervous system injury.

Zebrafish Integrin-Linked Kinase (ILK) interaction partners

  1. Heart failure in recessive embryonic lethal zebrafish mutant main squeeze (msq) mutants is due to a mutation in the integrin-linked kinase (ilk) gene.

  2. The lost-contact mutant on chromosome 10 encodes a nonsense mutation (Y319X) associated with defective cardiomyocytes & endothelial cells that leads to severe myocardial dysfunction. There is epistatic regulation between laminin-alpha4, integrin, & Ilk.

  3. Data show that integrin-linked kinase is an essential component downstream of laminin and integrin alpha7, providing strengthening of skeletal muscle fibre adhesion with the extracellular matrix.

Human Integrin-Linked Kinase (ILK) interaction partners

  1. Twist-ITGB1 (show ITGB1 Antibodies)-FAK (show PTK2 Antibodies)/ILK pathway and their downstream signaling network dictate the Twist-induced EMT (show ITK Antibodies) process in human mammary epithelial cells and breast cancer cells

  2. Results indicated that ILK is imperative in the development and progression of oral squamous cell carcinoma.

  3. Periostin (show POSTN Antibodies) enhanced ensometrial stromal cell migration, invasion, and adhesion due to the ILK1/Akt (show AKT1 Antibodies) signal pathway.

  4. high extracellular concentration of phosphate induced senescence in cultured smooth muscle through the activation of IGF-1 (show IGF1 Antibodies) receptor and ILK overexpression

  5. our data suggest an essential role of PINCH1 (show LIMS1 Antibodies), ILK and ILKAP (show ILKAP Antibodies) for the radioresistance of p53 (show TP53 Antibodies)-wildtype glioblastoma multiforme cells

  6. ILK inhibition and knockdown effects senescence in an Rb-dependent manner.

  7. ILK may have an important role in the progression of NSCLC, possibly through up-regulation of Snail (show SNAI1 Antibodies) and MRP1 (show MDM4 Antibodies).

  8. integrin linked kinase may play a role in cell proliferation, and cell migration in aggressive thyroid cancers.

  9. knockdown of ILK inhibits glioma cell migration, invasion and proliferation through upregulation of E-cadherin (show CDH1 Antibodies) and downregulation of cyclin D1 (show CCND1 Antibodies). Our results suggest that ILK may serve as a promising therapeutic target for glioma.

  10. Overexpression of CD29 (show ITGB1 Antibodies) decreased E-cadherin (show CDH1 Antibodies), but increased fibronectin (show FN1 Antibodies), vimentin (show VIM Antibodies), ILK activity.

Cow (Bovine) Integrin-Linked Kinase (ILK) interaction partners

  1. Integrin-linked kinase (ILK, MGC129022) is an important regulator of the endothelial phenotype and vascular network formation by directing the assembly and/or maturation of alpha5beta1-competent matrix-forming adhesions.

  2. Rac1 only partially restores the spreading defects of integrin linked kinasse (ILK)-depleted cells, suggesting that an additional ILK-dependent signal is required for cell spreading.

  3. Profilin (show PFN1 Antibodies)-dependent dissociation of G-actin (show ACTB Antibodies)-Tbeta4 complexes simultaneously liberates actin for filament assembly and facilitates Tbeta4 binding to integrin-linked kinase (ILK) in the lamellipodia.

Integrin-Linked Kinase (ILK) Antigen Profile

Protein Summary

Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with ILK

  • Integrin linked kinase (Ilk) antibody
  • integrin-linked kinase (ILK) antibody
  • integrin-linked kinase (ilk) antibody
  • integrin-linked protein kinase (CpipJ_CPIJ016644) antibody
  • integrin-linked kinase (Bm1_20815) antibody
  • integrin-linked protein kinase (Tsp_07213) antibody
  • integrin-linked protein kinase (Tsp_07224) antibody
  • integrin-linked protein kinase (Tsp_15354) antibody
  • Integrin-linked protein kinase (ilk) antibody
  • integrin linked kinase (Ilk) antibody
  • integrin linked kinase (ilk) antibody
  • integrin-linked kinase (Ilk) antibody
  • AA511515 antibody
  • CG10504 antibody
  • CT29478 antibody
  • Dmel\\CG10504 antibody
  • DmILK antibody
  • ESTM24 antibody
  • ilk antibody
  • ILK-1 antibody
  • ILK-2 antibody
  • l(3)78Ca antibody
  • P59 antibody
  • p59ILK antibody
  • zgc:65842 antibody

Protein level used designations for ILK

CG10504-PA , CG10504-PB , Ilk-PA , Ilk-PB , Integrin-linked kinase , integrin linked kinase , integrin-linked protein kinase , integrin-linked kinase , Integrin-linked protein kinase , integrin binding protein kinase , loc , lost-contact , main squeeze , msq , zilk , beta-integrin-linked kinase , 59 kDa serine/threonine-protein kinase , integrin-linked kinase-2

GENE ID SPECIES
53573 Drosophila melanogaster
374018 Gallus gallus
446640 Xenopus laevis
709944 Macaca mulatta
6050160 Culex quinquefasciatus
6099066 Brugia malayi
10898169 Trichinella spiralis
10898276 Trichinella spiralis
10910217 Trichinella spiralis
100145644 Xenopus (Silurana) tropicalis
100194973 Salmo salar
16202 Mus musculus
393543 Danio rerio
100135559 Cavia porcellus
3611 Homo sapiens
170922 Rattus norvegicus
540207 Bos taurus
100173674 Pongo abelii
Selected quality suppliers for anti-Integrin-Linked Kinase (ILK) Antibodies
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